Search, discover, and connect with over 1,800 researchers, faculty members, and scholars across all departments of KNUST.
Department of Pharmacology
The researcher focuses on the synthesis and bioactivity of alkaloid cryptolepium, examining its role in human health, pharmacological applications, and interactions with antibiotics, as well as considerations for ethical plant-based medicine.
Department of Pharmacology
The researcher explores the role of biological stains and phytochemicals in plant extracts, particularly focusing on root compounds from Caesalpinia benthamiana, Paullinia pinnata, and Xylopia aethiopica. Their work highlights how phenolic properties can influence health outcomes and also examines Moringa oleifera's potential for natural product applications to enhance well-being.
Department of Pharmacology
The researcher's research focuses on the study of systemic immune responses, particularly those involving inflammation, chronic inflammation, and systemic autoimmunity. Their work spans diverse biological pathways, including allergic inflammation, immune response modulation by natural compounds like pleuromycin and hydroethanol, and systemic inflammation mechanisms such as Allergic asthma and inflammatory bowel disease. The researcher's studies utilize a combination of pharmacological agents, synthetic extracts, and functional biopsies to investigate the role of natural molecules in modulating systemic inflammation and their potential therapeutic applications.
Department of Pharmacology
The researcher's work centers on the intricate relationship between maternal histamine levels and pregnancy outcomes, particularly in pre-eclampsia scenarios. Their research encompasses several key areas: systematic reviews of histidine decarboxylase activity and diamine oxidase isoforms in placental genes, molecular mechanisms using RNA analysis techniques, experimental models to study histamine effects, and discussions on the interplay between histamine receptors and fetal development. This research aims to elucidate how maternal histamine influences pregnancy, with a focus on understanding its role in pre-eclampsia and fetal gene expression changes.
Department of Pharmacology
The researcher's work is focused on the intersection of technology and human behavior, with a particular emphasis on how cognitive processes, emotions, and health outcomes are influenced by technological advancements across diverse fields. Their research spans topics such as memory, emotion, aging, connectome studies, and long-term human behavior, all viewed through computational modeling and empirical investigations. This interdisciplinary approach underscores the importance of understanding how technology impacts mental health in ways that involve both behavioral and biological dimensions, aiming to inform effective interventions for improved well-being.
Department of Pharmacology
The researcher focuses on examining the effects of plant-derived metabolites across diverse biological domains. Their work investigates how alkaloidal seeds (e.g., Picralima nitida) modulate inflammation in rats with IBD, while acariaceae plants like Pseudospondias microcarpa may influence brain disorders through behavioral changes under chronic stress. Additionally, their metabolic studies using seeds such as picralima nitida reveal potential impacts on mood or other health aspects.
Department of Pharmacology
The researcher investigates the effects of specific plant and alkaloid extracts on mental health and body chemistry in animal models, focusing on neurotransmission, antidepressant-like properties, neuroinflammation, and antipsychiatry. They employ extracts such asmallotus oppositifolius, Pseudospondias microcarpa hydroethanolic leaf extract, and Xylopic acid to study their roles in extended-brain axis modulation, axon effects, antidepressant activity, and cognitive dysfunction. The research bridges pharmacology, neuroscience, and biochemistry, using animal models like zebrafish and rabbits for extended-brain axis studies and clinical trials. The findings aim to advance understanding of mental health treatments through novel chemical approaches and provide insights for developing antipsychiatry strategies.
Department of Pharmacology
The researcher's work focuses on integrating machine learning, game theory, and behavioral economics to develop comprehensive models for understanding financial market dynamics. By combining computational methods with empirical data from diverse studies, they aim to create frameworks that bridge the gap between theoretical models and practical applications in finance. This integrated approach seeks to address common challenges in modeling complex economic systems, leveraging both quantitative techniques and qualitative insights to provide a deeper understanding of financial behavior.
Department of Pharmacology
The researcher has conducted extensive experimental mathematics across diverse fields, employing computational methods to explore intricate problems in algebraic geometry, combinatorics, theoretical computer science, quantum computing, machine learning, network modeling, fluid dynamics, condensed matter theory, statistical mechanics, high energy physics, and astrophysics. Their work integrates theoretical insights with practical computational techniques to advance our understanding of natural phenomena across disciplines.