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Gustav Komlaga

Pharmacognosy

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About

I am an Associate Professor of Pharmacognosy at KNUST, with a dual academic background, holding a PhD in Pharmacognosy (KNUST, Kumasi, Ghana) and Microbiology (University of Paris-Saclay, Chatenay Malabry, France). My interdisciplinary training empowers me to approach the field of natural products research with a comprehensive understanding of both the botanical and microbiological sciences.As a dedicated Natural Products Scientist, my research focuses on exploring medicinal plants for their potential therapeutic applications, with a special emphasis on infectious diseases such as malaria. I am committed to validating the efficacy and safety of herbal medicines traditionally used in Ghanaian communities, aiming to bridge the gap between traditional knowledge and modern scientific inquiry. Through my work, I seek to provide robust scientific evidence to support the rational and effective use of medicinal plants, thereby facilitating their acceptance in both local and global healthcare settings.My research also extends to the discovery of novel bioactive compounds from medicinal plants, with the goal of identifying drug candidates for the treatment of various diseases. Additionally, I am passionate about documenting and preserving the rapidly diminishing traditional knowledge of medicinal plant use, particularly among the communities in Northern Ghana and the Volta Region, where the health benefits of leafy vegetables are often overlooked.Currently, I am leading translational research efforts aimed at developing herbal products that are not only effective but also safe, ensuring they meet global healthcare standards. I strive to contribute to the creation of sustainable and accessible health solutions, particularly in resource-limited settings.With over 20 peer-reviewed publications in prestigious scientific journals, I have also contributed to numerous local and international conferences, furthering discourse on the potential of natural products in modern medicine. My expertise has led me to serve as an editorial board member and peer reviewer for several esteemed journals, including Journal of Ethnopharmacology, Phytochemistry Letters, Parasitology Research, Evidence-based Complementary and Alternative Medicine, Advances in Medicinal Plant Research, African Journal of Biotechnology, Journal of Drug Development and Clinical Trials, and International Journal of Pharmaceutical Science and Developmental Research.In addition to my academic and research commitments, I am an active member of professional organizations such as the University Teachers Association of Ghana (UTAG), the Pharmaceutical Society of Ghana (PSGH), and the West African Network of Natural Products Research Scientists (WANNPRES).I completed my O'Level education at Asuom Secondary School in the Eastern Region of Ghana and my A'Level studies at Mawuli School in Ho, Volta Region.

Research Summary

(inferred from publications by AI)

The overall research focus is centered around innovative plant-based treatments for health conditions, employing diverse methodologies such as traditional pharmacology, bioactivity studies, and synthetic approaches to address various therapeutic needs across different organisms.

Research Themes

All Papers

Toxicity and Safety Implications of Herbal Medicines Used in Africa(2019)
Medicinal plants and finished marketed herbal products used in the treatment of malaria in the Ashanti region, Ghana(2015)
Antimalarial Properties of <i>Sida cordifolia</i> L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression(2023)
In vitro antiproliferative activities of some Ghanaian medicinal plants(2024)
Ethnobotanical study of medicinal plants used to treat HIV, cancer and diabetes in some communities of Ashanti Region, Ghana(2023)
ANTIMICROBIAL ACTIVITY OF Hymenostegia afzelii AND Napoleanea vogelii(2006)
Evaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market(2020)
Antimicrobial Activity Of Essential Oils Of &lt;i&gt;Xylopia aethiopica&lt;/i&gt;(2008)
The Antimalarial Potential of Three Ghanaian Medicinal Plants(2015)
Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.(2021)
Antileishmanial and Trypanocidal Activities of Extracts and Aporphine Alkaloids Isolated from Monodora Genus (Annonaceae)(2017)
Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana(2016)
Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine(2017)
Search for antiplasmodial compounds from Ghanaian medicinal plants(2015)
Phytochemical, Antimicrobial, and Antioxidant Profiles of <i>Duranta erecta</i> L. Parts(2019)
Safety evaluation of hydroethanolic fruit extracts of Duranta erecta Linn(2022)
Safety evaluation of hydroethanolic fruit extracts of Duranta erecta Linn(2022)
Influence of variety and growth environment on β-amylase activity of flour from sweet potato (Ipomea batatas)(2009)
Antibacterial, anti-inflammatory, and antioxidant effects of the leaves and stem bark of Glyphaea brevis (Spreng) Monachino (Tiliaceae): A comparative study(2011)
Antiypertensive action of ethanolic extract of Imperata cylindrica leaves in animal models.(2010)
Cassane diterpenoids from stem bark of Erythrophleum suaveolens [(Guill. et Perr.), Brenan](2015)
Pharmacognostic Standardization of the Leaves and Root Bark of Caesalpinia benthamiana(2011)
Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens(2020)
Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts(2020)
Hura crepitans stem bark extract: A potential remedy to sub-acute liver damage(2021)
Toxicity of the Hydroethanolic Leaves Extract of Duranta erecta L. in Rat Models(2020)
Extracts of Hura crepitans L. stem bark attenuate liver injury and inflammation induced by CCl4 in rats(2020)
Toxicity of the Hydroethanolic Leaves Extract of Duranta erecta L. in Rat Models(2020)
<i>Duranta erecta</i> L. extracts exert hepatoprotective effect on CCl4-induced toxicity via inactivating NF-kB pathway(2025)
Acaricidal effect of an isolate from Hoslundia opposita vahl against Amblyomma variegatum (Acari: Ixodidae)(2011)
Pyrrolidine alkaloids and their glycosylated derivatives from the root bark of Dichrostachys cinerea (L) Wight &amp; Arn. (Fabaceae)(2016)
Hypoglycaemic and Antioxidant Activities of the Stem Bark of Morinda Lucida Benth in Streptozotocin – Induced Diabetic Rats(2011)
A bioactive fraction from the leaves of Ceiba pentandra (L.) Gaertn. exhibits antiproliferative activity via cell cycle arrest at the G1/S checkpoint and initiation of apoptosis via poly [ADP-ribose] polymerase 1 (PARP1) cleavage in HeLa cells.(2025)
Hepatoprotective Potential of Hura crepitans L.: A Review of Ethnomedical, Phytochemical and Pharmacological Studies(2020)
Phytochemical, Antioxidant and Safety Evaluation of Hura crepitans (L.) Stem Bark Hydroethanolic Extract in Animals(2020)
In vitro cytotoxic activity of five Ghanaian plants on human cancer cell lines(2024)
Antidiabetic Activity of a Ghanaian Herbal Product, DBT-57A: An Observational Study(2025)
Anti-Inflammatory, Antioxidant, and Selective Antibacterial Effects of &lt;i&gt;Euadenia eminens&lt;/i&gt; Root Bark(2012)
Flavonoid constituents of the mature fruit of Tetrapleura tetraptera schum. Et Thonn.)(2006)
Malaria: Epidemiology, Life Cycle of Parasite, Control Strategies and Potential Drug Screening Techniques(2024)
Vegetative growth of different strains of Pleurotus and Lentinula species on cassava (Manihot esculenta) and yam (Dioscorea rotundata) wastes in Ghana.(2014)
Phytochemistry, proximate and antioxidant properties of some indigenous leafy vegetables(2019)
Proceedings of quarter 2 and year 2 project review meeting. Final report 2 on project outputs 5.1, 5.2 and 5.3. Food Research Institute (FRI), Accra, Ghana. 19 pp.(2004)
The Antimalarial Potential of Three Ghanaian Medicinal Plants(2015)
In Vitro Cytotoxic Activity of Five Ghanaian Plants on Human Cancer Cell Lines(2024)
A review of preclinical evidence of Cryptolepis nigrescens (Wennberg) L. Joubert. and Bruyns., Prosopsis africana (Guill. and Perr.) Taub. and Pterygota macrocarpa K. Schum. traditionally used to manage tumours in Ghana(2023)
Antimalarial activity of the aqueous extract and anthraquinones from the root of Senna siamea (LAM) H.S. Irwin &amp; Barneby (Fabaceae).(2025)

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.