Isaac Donkor
This researcher has focused on synthesizing novel heterocyclic compounds and exploring their roles in understanding chiral centers, biological activity, and reactivity. Their work encompasses the development of synthetic frameworks for calpain inhibitors, quinazolines, bisbenzamidines, and dihydrophenoxiamides, which have significant applications in treating conditions such as Alzheimer's disease, Leishmaniasis, and pseudomonas species resistance. The research also investigates the role of these compounds in cognitive function, neurodegenerative diseases, and the impact of anti-Pneumocystis carinii activity in preventing pneumonia. Additionally, their studies highlight the importance of molecular modeling and chiral properties in elucidating the mechanisms behind disease progression and drug efficacy.
Aldose Reductase and Taurine
Alzheimer's disease research and treatments
Analytical Chemistry and Chromatography
Calpain Protease Function and Regulation
Cell death mechanisms and regulation
Chemical Synthesis and Analysis
Dental Health and Care Utilization
Drug Transport and Resistance Mechanisms
Free Radicals and Antioxidants
Molecular spectroscopy and chirality
Multicomponent Synthesis of Heterocycles
Neuroscience and Neuropharmacology Research
Phenothiazines and Benzothiazines Synthesis and Activities
Pneumocystis jirovecii pneumonia detection and treatment
Quinazolinone synthesis and applications
Research on Leishmaniasis Studies
Synthesis and biological activity
Synthesis and Biological Evaluation
Synthesis and Characterization of Heterocyclic Compounds
Synthesis and Reactions of Organic Compounds
Synthesis and Reactivity of Heterocycles
Trypanosoma species research and implications
Department of Painting and Sculpture
Kwame Nkrumah University of Science and Technology