AD
Department of Medical DiagnosticsHealth SciencesLife Sciences

Albert Dompreh

51 Publications23 Research Themes43 Open Access
Research Overview & Focus

The researcher has conducted extensive research across multiple themes within health sciences, focusing on infectious diseases, parasitic infections, immunological studies, pharmacokinetics and treatments for diseases such as TB, HIV/AIDS, and HIV-related complications. Key findings include a strong emphasis on the prevalence of parasitic infections like Helicobacter pylori and HIV-1 RNA loads in Ghanaian individuals, as well as the effectiveness of antituberculosis drugs in reducing viral load markers. The researcher has also explored molecular mechanisms underlying disease transmission, such as retroviral loads in HIV patients and bacterial colonization with Toxoplasma gondii. Additionally, they have investigated therapeutic interventions like efavirenz and Nevirapine for reducing HIV suppression outcomes in adolescents. Their work underscores the importance of understanding immune responses and viral dynamics to develop more effective treatments.

Key Research Themes (23)
Health Sciences

Amoebic Infections and Treatments

Health Sciences

Antimicrobial Resistance in Staphylococcus

Health Sciences

Blood Pressure and Hypertension Studies

Health Sciences

Drug Transport and Resistance Mechanisms

Health Sciences

Helicobacter pylori-related gastroenterology studies

Health Sciences

Hepatitis B Virus Studies

Health Sciences

Hepatitis C virus research

Health Sciences

HIV-related health complications and treatments

Health Sciences

HIV/AIDS drug development and treatment

Health Sciences

HIV/AIDS Research and Interventions

Life Sciences

Parasites and Host Interactions

Health Sciences

Parasitic Diseases Research and Treatment

Life Sciences

Parasitic Infections and Diagnostics

Health Sciences

Parvovirus B19 Infection Studies

Health Sciences

Pharmaceutical studies and practices

Life Sciences

Reproductive tract infections research

Health Sciences

Rheumatoid Arthritis Research and Therapies

Health Sciences

SARS-CoV-2 detection and testing

Health Sciences

Syphilis Diagnosis and Treatment

Life Sciences

Toxoplasma gondii Research Studies

Health Sciences

Tuberculosis Research and Epidemiology

Health Sciences

Viral Infections and Immunology Research

Health Sciences

Whipple's Disease and Interleukins

Publications (51)

Determinants of Entero-Invasive and Non-Entero-Invasive Diarrheagenic Bacteria Among HIV-Positive and HIV-Negative Adults in Ghana

Open Access

Assessment of Cryptosporidium spp. Sub-Families and Giardia duodenalis Assemblages A and B in Ghanaian HIV Patients, Including Socio-Economic, Clinical, and Immunological Associations

Open Access

Associations of HIV status and the abundance of blaCTX-M and vanB resistance genes in stool samples of Ghanaian individuals

Open Access
2025Antimicrobial Resistance in StaphylococcusDOI: 10.1556/1886.2025.00061

Evaluation of Each Three Entamoeba histolytica- and Strongyloides stercoralis-Specific Real-Time PCR Assays Applying Test Comparisons Without Reference Standards

Open Access
2025Amoebic Infections and TreatmentsDOI: 10.3390/microorganisms13091976

Tenofovir diphosphate concentrations in dried blood spots predict future HIV suppression but not virologic failure in adolescents with HIV

2025HIV/AIDS Research and InterventionsDOI: 10.1097/qad.0000000000004245

Epidemiological, clinical and immunological features of Schistosoma spp., Stronglyoides stercoralis and Taenia spp. infections in Ghanaian HIV patients

Open Access
2025Parasites and Host InteractionsDOI: 10.1556/1886.2025.00031

Comparative epidemiology of Ghanaian individuals with molecular proof of Entamoeba histolytica with and without concomitant human immunodeficiency virus infection

Open Access
2025Amoebic Infections and TreatmentsDOI: 10.1556/1886.2025.00030

Pharmacokinetics of Tenofovir Diphosphate, Lamivudine Triphosphate and Emtricitabine Triphosphate in Adolescents With HIV Infection With and Without Tuberculosis Coinfection

2025HIV/AIDS drug development and treatmentDOI: 10.1097/inf.0000000000004831

Epidemiological, Clinical, and Immunological Features of Ghanaian People-Living-with-HIV (Human Immunodeficiency Virus) and Molecular Proof of Cystoisospora belli in Their Stool Samples

Open Access
2025Parasitic Infections and DiagnosticsDOI: 10.3390/pathogens14030212

Association of Molecular Detections of Microsporidia in Stool Samples with Clinical and Immunological Parameters in Ghanaian HIV Patients

Open Access
2024Parasitic Infections and DiagnosticsDOI: 10.3390/pathogens13121053

Replicative co-infections with human immunodeficiency virus 1 and 2 as well as hepatitis B and C virus in Ghanaian individuals

Open Access
2024Hepatitis B Virus StudiesDOI: 10.1556/1886.2024.00103

High Clinical Burden of Cryptosporidium spp. in Adult Patients with Acquired Immunodeficiency in Ghana

Open Access
2024Parasitic Infections and DiagnosticsDOI: 10.3390/microorganisms12112151

Demographic, Clinical Profile of Rheumatoid Arthritis Patients and Their Association with Disease Severity in Ghana

Open Access
2024Rheumatoid Arthritis Research and TherapiesDOI: 10.1155/2024/6639079

Very low prevalence of Mansonella perstans-specific cell-free DNA in serum samples of Ghanaian HIV patients

Open Access
2023Parasitic Diseases Research and TreatmentDOI: 10.1556/1886.2023.00028

Pharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg

Open Access
2023HIV/AIDS drug development and treatmentDOI: 10.1097/qad.0000000000003576

The Clinical Features and Immunological Signature of Cyclospora cayetanensis Co-Infection among People Living with HIV in Ghana

Open Access
2022Parasitic Infections and DiagnosticsDOI: 10.3390/microorganisms10071407

Screening for Schistosoma spp. and Leishmania spp. DNA in Serum of Ghanaian Patients with Acquired Immunodeficiency

Open Access
2022Parasites and Host InteractionsDOI: 10.3390/pathogens11070760

Policy adherence and clinical effect of early infant diagnosis of HIV exposed children: impact on Elimination of mother to child transmission (EMTCT

Open Access
2022HIV/AIDS Research and InterventionsDOI: 10.31191/afrijcmr.v5i1.84

A Comparative Study Between Nasopharyngeal/Oropharyngeal, Faecal and Saliva Viral Shedding In Ghanaian COVID-19 Patients attending Komfo Anokye Teaching Hospital (KATH), Kumasi from October – December, 2020

Open Access
2021SARS-CoV-2 detection and testingDOI: 10.1101/2021.09.04.21262932

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana

Open Access
2021Whipple's Disease and InterleukinsDOI: 10.3390/microorganisms9081781

Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection

Open Access
2021HIV/AIDS drug development and treatmentDOI: 10.1016/j.meegid.2021.104856

Effect of malnutrition on the pharmacokinetics of anti-TB drugs in Ghanaian children

Open Access
2021Pharmaceutical studies and practicesDOI: 10.5588/ijtld.20.0301

Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana

Open Access
2020Viral Infections and Immunology ResearchDOI: 10.3390/v12020221

Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana

Open Access
2019Parasitic Infections and DiagnosticsDOI: 10.1371/journal.pone.0224000

Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana

Open Access
2019Parasitic Infections and DiagnosticsDOI: 10.1371/journal.pone.0221968

Effect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old

Open Access
2019HIV/AIDS drug development and treatmentDOI: 10.1128/aac.00839-19

Prevalence and the evaluation of culture, wet mount, and ELISA methods for the diagnosis of Trichomonas vaginalis infection among Ghanaian women using urine and vaginal specimens

Open Access
2019Reproductive tract infections researchDOI: 10.1186/s41182-019-0162-9

Population pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing

Open Access
2019HIV/AIDS drug development and treatmentDOI: 10.1093/jac/dkz238

Sero-prevalence of Hepatitis B and C viral co-infections among HIV-1 infected ART-naïve individuals in Kumasi, Ghana

Open Access
2019Hepatitis B Virus StudiesDOI: 10.1371/journal.pone.0215377

Effect of Rifampin-Isoniazid-Containing Antituberculosis Therapy on Efavirenz Pharmacokinetics in HIV-Infected Children 3 to 14 Years Old

Open Access
2018HIV/AIDS drug development and treatmentDOI: 10.1128/aac.01657-18

Levels of pro-inflammatory biomarkers among HIV patients on highly active antiretroviral therapy (HAART) and HAART naive patients

Open Access
2018HIV-related health complications and treatmentsDOI: 10.30574/gscbps.2018.4.2.0056

Levels of pro-inflammatory biomarkers among HIV patients on highly active antiretroviral therapy (HAART) and HAART naive patients

Open Access
2018HIV-related health complications and treatmentsDOI: 10.5281/zenodo.4305979

Correlation of Haematological Parameters with TNF-α and Interleukin (IL-6) in Seropositive HIV Patients on Highly Active Antiretroviral Therapy (HAART) and HAART Naïve Patients

2018HIV-related health complications and treatments

Evaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations

Open Access
2018Tuberculosis Research and EpidemiologyDOI: 10.1128/aac.00008-18

Effect of Genetic Variation of <i>NAT2</i> on Isoniazid and <i>SLCO1B1</i> and <i>CES2</i> on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis

Open Access
2017Drug Transport and Resistance MechanismsDOI: 10.1128/aac.02099-17

Profiling of cardio‐metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study

Open Access
2017Blood Pressure and Hypertension StudiesDOI: 10.1186/s40169-017-0162-5

Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children

Open Access
2017Tuberculosis Research and EpidemiologyDOI: 10.1097/inf.0000000000001687

Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection

Open Access
2016Tuberculosis Research and EpidemiologyDOI: 10.1128/aac.01701-16

Seroprevalence of Toxoplasma gondii Infection among Pregnant Women in the Ashanti Region of Ghana

Open Access
2016Toxoplasma gondii Research StudiesDOI: 10.6084/m9.figshare.5675194.v1

Helicobacter pylori Infection Is Associated with Higher CD4 T Cell Counts and Lower HIV-1 Viral Loads in ART-Naïve HIV-Positive Patients in Ghana

Open Access
2015Helicobacter pylori-related gastroenterology studiesDOI: 10.1371/journal.pone.0143388

Pattern and predictors of immunologic recovery in HIV infected patients

Open Access
2015HIV/AIDS Research and InterventionsDOI: 10.1186/s13104-015-1406-3

<i>Helicobacter pylori</i>Coinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana

Open Access
2015Helicobacter pylori-related gastroenterology studiesDOI: 10.1093/cid/civ577

Pharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection

Open Access
2015Tuberculosis Research and EpidemiologyDOI: 10.1093/jpids/piv035

The immunological response of HIV-positive patients initiating HAART at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Open Access
2013HIV/AIDS Research and Interventions

Ear, nose and throat lesions in hiv/aids patients in komfo anokye teaching hospital, kumasi, ghana.

2012Syphilis Diagnosis and Treatment

Antibody Detection and Kinetics of Antibody Production during Early Stages of Immunization with Hepatitis B Virus Vaccine

Open Access
2007Hepatitis B Virus StudiesDOI: 10.1128/cvi.00158-07

immunization with Hepatitis B virus vaccine

2007Hepatitis B Virus Studies

Maternal‐Fetal Transmission of Human Parvovirus B19 Genotype 3

Open Access
2006Parvovirus B19 Infection StudiesDOI: 10.1086/506450

GB virus C genotype 1 is rarely transmitted vertically but acquired during infancy in West Africa

2006Hepatitis C virus researchDOI: 10.1097/01.aids.0000233583.02586.14

GB virus C and HIV-1 RNA load in single virus and co-infected West African individuals

2006Hepatitis C virus researchDOI: 10.1097/01.aids.0000200536.79360.03

Vertical transmission of HIV in Ghanaian women diagnosed in cord blood and post‐natal samples

2005HIV/AIDS Research and InterventionsDOI: 10.1002/jmv.20463
Academic Metrics
DepartmentDepartment of Medical Diagnostics
Total Publications51
Research Themes23
Open Access Papers43

Department of Medical Diagnostics

Kwame Nkrumah University of Science and Technology

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