Reimmel Kwame Adosraku
The researcher has conducted extensive work on bioactive compounds derived from natural products across diverse families, employing methodologies such as NMR lipid profiles and high-resolution mass spectrometry for characterization. These compounds, including plumbagin from *Plumbago zeylanica* and Xylopia aethiopica from *Xylopia aethiopica*, hold significant potential in health sciences for therapeutic applications. The researcher also explores antimicrobial residues, highlighting the importance of proper handling to prevent adverse effects in public health settings. Through these integrative approaches, the focus is on understanding and developing natural products with specific health benefits across pharmacology, biochemistry, and environmental impact assessments.
Faculty Biography
Reimmel K Adosraku completed his BPharm programme at KNUST with a 2nd Class Upper degree in 1980. After a 1-year national service in the Department of Pharmaceutical Chemistry, KNUST, he enrolled in the MPhil programme in Pharmaceutical Chemistry in 1981, which programme he successfully completed in 1984 and was employed as lecturer in the same department in 1984. In October 1990, he was admitted into the University of London School of Pharmacy, the premier School of Pharmacy in the UK, for a PhD programme in Bioanalytical Chemistry. He successfully completed the programme and returned to post in June 1994. Reimmel became instrumental in the promotion and application of high performance liquid chromatography (hplc) in the university. This greatly enhanced research in the department and turned out many Pharmaceutical Analysts for the pharmaceutical industries in Ghana who could apply this versatile technique in the analysis of medicines and other chemicals. He also introduced the practice of 'bench fees' in the department which provided essential funds for provision of research inputs so that graduate students were able to complete their programmes on schedule. This practice was later adopted by the university.
Amoebic Infections and Treatments
Bee Products Chemical Analysis
Bioactive Compounds and Antitumor Agents
Biosimilars and Bioanalytical Methods
Carbohydrate Chemistry and Synthesis
Crystallization and Solubility Studies
Essential Oils and Antimicrobial Activity
HIV/AIDS drug development and treatment
Medicinal Plants and Neuroprotection
Metabolomics and Mass Spectrometry Studies
Microbial infections and disease research
Microbial Natural Products and Biosynthesis
Moringa oleifera research and applications
Natural product bioactivities and synthesis
Pesticide Residue Analysis and Safety
Pharmaceutical Quality and Counterfeiting
Pharmaceutical studies and practices
Pharmacological Effects of Natural Compounds
Phytochemicals and Antioxidant Activities
Phytochemistry and Biological Activities
Piperaceae Chemical and Biological Studies
Synthesis and biological activity
Traditional and Medicinal Uses of Annonaceae
Trypanosoma species research and implications
A comparative study of Ghanaian propolis extracts: Chemometric analysis of the chromatographic profile, antioxidant, and hypoglycemic potential and identification of active constituents
Open AccessBioequivalence studies of cetirizine tablets using the urine excretion data of healthy Ghanaian male volunteers
Open AccessA Comparative Study of Ghanaian Propolis Extracts: Chemometric Analysis of the Chromatographic Profile, Antioxidant, and Hypoglycaemic Potential and Identification of Active Constituents
Open AccessBioequivalence Study of Locally Manufactured Cetirizine Tablets in Ghana
Open AccessCorrection to: Detection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method
Open AccessDetection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method
Open AccessA Simple RP-HPLC Method to Simultaneously Assay the Contents of Lamivudine, Tenofovir, and Nevirapine in Fixed Dose Combined Oral Antiviral Medicines
Open AccessExposure of consumers to substandard antibiotics from selected authorised and unauthorised medicine sales outlets in Ghana
Open AccessEvaluation of the Haematinic Activities of Extracts of Justicia secunda Vahl Leaves in Red Blood Cells of Laboratory Rats
Open AccessEvaluation of the Haematinic Activities of Extracts of <i>Justicia secunda</i> Vahl Leaves in Red Blood Cells of Laboratory Rats
Open AccessMALDI–HRMS imaging and HPLC–HRESI–MS<sup><i>n</i></sup> characterisation of kaurane diterpenes in the fruits of <scp><i>Xylopia aethiopica</i></scp> (Dunal) A. Rich (Annonaceae)
Resistance Modulation Action, Time-Kill Kinetics Assay, and Inhibition of Biofilm Formation Effects of Plumbagin from <i>Plumbago zeylanica</i> Linn
Open AccessInvestigation of Acid-Base Indicator Property of Plumbagin from<i>Plumbago zeylanica</i>Linn
Open AccessVeterinary Medicine and Pharmaceuticals
Open AccessAntimicrobial Activities of Novel Xylopic Acid Derivatives
Open AccessSubstandard antibacterial agents in the formal and informal medicine outlets in Ghana: Still myth or reality?
Antibacterial secondary metabolites from an endophytic fungus, Fusarium solani JK10
LC–HRESI–MS/MS Profiling of Flavonoids from Chlorophora regia (Moraceae)
CCDC 1487779: Experimental Crystal Structure Determination
Open AccessAssessment of bioequivalence profile of locally produced flucloxacillin sodium capsules via urinary excretory rates
Open AccessEffects of an ethanol extract and the diterpene, xylopic acid, of <i>Xylopia aethiopica</i> fruits in murine models of musculoskeletal pain
Open AccessSynthesis and Characterization of Novel Xylopic Acid Derivatives
Open AccessEthnopharmacological Importance of Xylopia aethiopica (DUNAL) A. RICH (Annonaceae) - A Review
Open AccessPrenylated 2-arylbenzofuran derivatives with potent antioxidant properties from Chlorophora regia (Moraceae)
SYNTHESIS AND EVALUATION OF ANTIMICROBIAL PROPERTIES OF AZO DYES
Investigating the In-vivo Antiplasmodial Properties of Aqueous Extract of Moringa oleifera Lam (Moringaceae) Leaves
CHARACTERIZATION AND HPLC QUANTIFICATION OF PIPERINE ISOLATED FROM PIPER GUINEENSE (Fam. PIPERACEAE)
Evaluation of the antioxidant and free radical scavenging properties of <i>Secamone afzelii</i> Rhoem.
An HPLC method for the direct assay of the serotonin precursor, 5‐hydroxytrophan, in seeds of<i> Griffonia simplicifolia</i>
Tetrahymena thermophila: analysis of phospholipids and phosphonolipids by high-field 1H-NMR
Proton Nuclear Magnetic Resonance Lipid Profiling of Intact Platelet Membranes
NMR lipid profiles of cells, tissues, and body fluids: proton NMR analysis of human erythrocyte lipids.
Open AccessNuclear magnetic resonance and chromatographic studies of host and parasite lipids
Proton NMR lipid profile of Leishmania donovani promastigotes
Department of Pharmaceutical Chemistry
Kwame Nkrumah University of Science and Technology