Edwin Ferguson Laing
Department of Molecular MedicineHealth SciencesLife SciencesPhysical Sciences

Edwin Ferguson Laing

29 Publications16 Research Themes21 Open Access
Research Overview & Focus

The researcher's work in health sciences is centered on understanding the interplay between various biological factors that contribute to cardiovascular disease and other health risks. Their studies span themes such as vitamin D status, glucose metabolism, lipid profiles, metabolic diseases, genetics, anemia, blood pressure, and diabetes. They examine associations with conditions like insulin resistance, glycemic control, cholesterol profiles, and metabolic syndromes, using case-control studies. Additionally, they explore genetic and epidemiological aspects of conditions like sickle cell anemia and sphenocentrum jollyanum root extraction effects. Their research aims to identify high-risk individuals in populations such as Ghana, focusing on preventive strategies and understanding the role of diet, metabolism, lipid dynamics, and genetic factors in disease progression.

Faculty Biography

Edwin F. Laing is a Fellow of the Ghana College of Physicians (Laboratory Medicine Division). He is a Clincal Biochemist by training and employed as a Consultant Clinical Biochemist at the Komfo Anokye Teaching Hospital (KATH) and as an Associate Professor of Chemical Pathology at the Department of Molecular Medicine, School of Medicine and Dentistry, KNUST with over 30 years of university teaching, and research experience. He holds a Ph.D. in Biochemistry and Molecular Biology and an MSc. in Clinical Biochemistry both from the University of Leeds in the United Kingdom. He holds a Bachelor of Medicine and a Bachelor of Surgery (MB ChB) and a Bachelor of Science in Human Biology from the University of Science and Technology, Kumasi, Ghana. He obtained his Ordinary and Advanced Level Certificates at  Adisadel College, Cape Coast, Ghana.University administrative positions held by Edwin F. Laing include: Head, Department of Molecular Medicine, Head, Department of Sonography, Departmental Examinations Officer, Head : Departmental Curriculum Review Committee, School Examinations Officer, Member of the School Board and Member of the College Board.Positions held at KATH include Physician-In-Charge of the Wednesday Diabetes Clinic  which he started and Head of the Department of Clinical Biochemistry.He was a Member of the Faculty Board for Laboratory Physicians of the Ghana College of Physicians. He was also a Member of the Technical Advisory Committee on Clinical Trials (TAC-CT) for the Food and Drugs Authority (FDA), Ghana. He acted as a reviewer for the KNUST as well as College of Health Sciences Research Funds. Edwin F. Laing was nominated by the Medical and Dental Council of the Gambia (MDCG) to review accreditation documents of the American International University West Africa (AIUWA) in Biochemistry and Chemical Pathology.Edwin F. Laing’s area of research is Metabolic Medicine with a focus on Metabolic Syndrome, Insulin Resistance, Diabetes Mellitus, Thyroid function and Vitamin D metabolism. He has been teaching at both undergraduate and postgraduate levels of Medical and Paramedical programmes of KNUST. He has supervised over 30 student projects at all levels (BSc, MSc, MPhil, PhD) from the year 2000.  He was External Examiner for the Level 400 examinations in Chemical Pathology at the University of Ghana Medical School. He acted as assessor for promotion to an academic position for one University in Ghana.Edwin F. Laing has considerable clinical and laboratory exposure. He was a Member of and now an Affiliate of the American Association for Clinical Chemistry (AACC), a member of the Ghana Medical Association (GMA), a Member of the University Teachers Association of Ghana (UTAG) and a member of the Ghana Science Association (GSA).

Key Research Themes (16)
Health Sciences

Adipokines, Inflammation, and Metabolic Diseases

Health Sciences

Anesthesia and Sedative Agents

Health Sciences

Blood Pressure and Hypertension Studies

Health Sciences

Diabetes, Cardiovascular Risks, and Lipoproteins

Health Sciences

Diet, Metabolism, and Disease

Health Sciences

Erythropoietin and Anemia Treatment

Health Sciences

Folate and B Vitamins Research

Life Sciences

Genetic Associations and Epidemiology

Health Sciences

Hemoglobinopathies and Related Disorders

Health Sciences

Iron Metabolism and Disorders

Health Sciences

Parathyroid Disorders and Treatments

Physical Sciences

Polar Research and Ecology

Health Sciences

Prostate Cancer Diagnosis and Treatment

Health Sciences

Thyroid Disorders and Treatments

Health Sciences

Tuberculosis Research and Epidemiology

Health Sciences

Vitamin D Research Studies

Publications (29)

Association between vitamin D receptor gene variants and the risk of type 2 diabetes mellitus in a Ghanaian population

Open Access
2025Vitamin D Research StudiesDOI: 10.1038/s41598-025-96731-y

Diet-induced obesity influences atherogenic indices and increases risk of cardiovascular disease in male Wistar rats

Open Access
2025Diet, Metabolism, and DiseaseDOI: 10.31373/ejtcm/204959

Haplotype-Specific Genetic Epidemiology of Sickle Cell Anemia Patients in Accra, Ghana: Patterns, Clinical Implications, and Public Health Responses

2025Hemoglobinopathies and Related DisordersDOI: 10.1080/03630269.2025.2474609

Identification of hematological biomarkers and assessment of machine learning models for sickle cell anemia severity classification

Open Access
2025Hemoglobinopathies and Related DisordersDOI: 10.1093/jscdis/yoaf020

Differences in PPD- and mitogen-induced T-cell activation marker expression characterize immunopathology in acute tuberculosis patients

Open Access
2024Tuberculosis Research and EpidemiologyDOI: 10.1007/s10096-023-04741-3

Thyroid dysfunction and glycaemic control among Type 2 diabetes mellitus patients in Ghana: A comparative cross‐sectional study

Open Access
2023Thyroid Disorders and TreatmentsDOI: 10.1002/edm2.447

Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients

2023Tuberculosis Research and EpidemiologyDOI: 10.1016/j.humimm.2023.08.141

Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study

Open Access
2021Vitamin D Research StudiesDOI: 10.1155/2021/9987141

Profiling immuno-metabolic mediators of vitamin B12 deficiency among metformin-treated type 2 diabetic patients in Ghana

Open Access
2021Folate and B Vitamins ResearchDOI: 10.1371/journal.pone.0249325

Anthropometric indices and their cut-off points in relation to type 2 diabetes among Ghanaian migrants and non-migrants: The RODAM study

2021Diabetes, Cardiovascular Risks, and LipoproteinsDOI: 10.1016/j.diabres.2021.108687

Increased metformin dosage suppresses pro-inflammatory cytokine levels in systemic circulation and might contribute to its beneficial effects

2021Adipokines, Inflammation, and Metabolic DiseasesDOI: 10.1080/15321819.2020.1862861

Profiling Immuno-Metabolic Mediators of Vitamin B12 Deficiency Among Metformin-Treated Type II Diabetes Patients in Ghana

Open Access
2020Folate and B Vitamins ResearchDOI: 10.21203/rs.3.rs-117906/v1

Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population

Open Access
2020Diabetes, Cardiovascular Risks, and LipoproteinsDOI: 10.1016/j.heliyon.2020.e04583

Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

Open Access
2020Genetic Associations and EpidemiologyDOI: 10.1155/2020/3198671

Evaluation of serum iron overload, AST:ALT ratio and log10ferritin:AST ratio among schizophrenia patients in the Kumasi Metropolis, Ghana: a case–control study

Open Access
2019Iron Metabolism and DisordersDOI: 10.1186/s13104-019-4847-2

Prevalence of metabolic syndrome and the comparison of fasting plasma glucose and HbA1c as the glycemic criterion for MetS definition in non-diabetic population in Ghana

Open Access
2019Diabetes, Cardiovascular Risks, and LipoproteinsDOI: 10.1186/s13098-019-0423-0

Vitamin B<sub>12</sub> deficiency in type 2 diabetic patients on metformin: a cross-sectional study from South-Western part of Ghana

Open Access
2019Folate and B Vitamins ResearchDOI: 10.1080/20905068.2019.1662647

Nomogram for predicting the probability of the positive outcome of prostate biopsies among Ghanaian men

Open Access
2018Prostate Cancer Diagnosis and TreatmentDOI: 10.1016/j.afju.2017.09.004

Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis

Open Access
2018Vitamin D Research StudiesDOI: 10.1155/2018/9369282

Gender Specific Predictive Performance and Optimal Threshold of Anthropometric Indices for the Prediction of Hypertension among a Ghanaian Population in Kumasi

Open Access
2018Blood Pressure and Hypertension StudiesDOI: 10.9734/ajmah/2017/37772

Haemato-biochemical basis of anaemia in Agogo, Ashanti Region, Ghana

Open Access
2017Iron Metabolism and DisordersDOI: 10.4314/jmbs.v5i3.1

Vitamin D status and its association with insulin resistance among type 2 diabetics: A case -control study in Ghana

Open Access
2017Vitamin D Research StudiesDOI: 10.1371/journal.pone.0175388

An Analysis of Anthropometric Indicators and Modifiable Lifestyle Parameters Associated with Hypertensive Nephropathy

Open Access
2016Blood Pressure and Hypertension StudiesDOI: 10.1155/2016/6598921

Analysis of Atherogenic and Anthropometric Profiles of Normotensive and Hypertensive Ghanaians in the Kumasi Metropolis

2015Diabetes, Cardiovascular Risks, and LipoproteinsDOI: 10.9734/bjmmr/2015/14308

A Study of the Efficacy of Cardiac Antidysrhythmic Drugs in Attenuating Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation in the Black Population

Open Access
2014Anesthesia and Sedative AgentsDOI: 10.11648/j.ja.20130101.11

Relationship between parathyroid hormone and electrolytes in chronic kidney disease

2012Parathyroid Disorders and Treatments

Anxiogenic-like Effects of a Root Extract of Sphenocentrum jollyanum Pierre in Murine Behavioural Models

Open Access
2009Polar Research and EcologyDOI: 10.3923/jpt.2009.91.106

Anaemia as a Risk Factor for Cardiovascular Disease in Patients with Chronic Kidney Disease

2008Erythropoietin and Anemia TreatmentDOI: 10.3923/jms.2008.707.714

Lipid lowering among treated hypertensives in a Ghanaian population

2001Diabetes, Cardiovascular Risks, and LipoproteinsDOI: 10.4314/jgsa.v3i2.17920
Academic Metrics
DepartmentDepartment of Molecular Medicine
Total Publications29
Research Themes16
Open Access Papers21

Department of Molecular Medicine

Kwame Nkrumah University of Science and Technology

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