Sampson Antwi
99 Publications37 Research Themes69 Open Access
Research Overview & Focus
The research literature underscores a comprehensive approach to understanding neglected tropical diseases, particularly focusing on chronic kidney disease (CKD) in Ghana, where several themes such as neglected malaria research, immunology, HIV/AIDS prevention, andPediatric nephrology are addressed. Methodologies ranging from systematic reviews to clinical trials, pharmacokinetic studies, behavioral assessments, and economic evaluations are employed to explore the etiology, management, and prevention of CKD. These studies highlight the complex interplay between genetics, nutritional status, immunological markers, and social determinants in disease manifestation, emphasizing the need for integrated, multidisciplinary approaches for effective intervention.
Faculty Biography
Prof Sampson Antwi is a Professor of Child Health and Paediatric Nephrology in the School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi-Ghana.I am also a Paediatric HIV and Malnutrition Expert. I founded the paediatric renal clinic, the paediatric HIV clinic and the malnutrition unit all in Komfo Anokye Teaching Hospital, Kumasi-Ghana. The paediatric HIV clinic is the second largest paediatric HIV clinic in Ghana with over 500 patients.
Key Research Themes (37)
Health Sciences
Acute Kidney Injury Research
Health Sciences
Adolescent and Pediatric Healthcare
Health Sciences
Birth, Development, and Health
Health Sciences
Blood groups and transfusion
Health Sciences
Blood Pressure and Hypertension Studies
Health Sciences
Cancer Risks and Factors
Life Sciences
Cancer, Lipids, and Metabolism
Health Sciences
Child Nutrition and Water Access
Health Sciences
Chronic Kidney Disease and Diabetes
Health Sciences
COVID-19 Clinical Research Studies
Health Sciences
Dialysis and Renal Disease Management
Health Sciences
Disaster Response and Management
Health Sciences
Drug Transport and Resistance Mechanisms
Health Sciences
Food Security and Health in Diverse Populations
Health Sciences
Global Maternal and Child Health
Social Sciences
Global Public Health Policies and Epidemiology
Life Sciences
Hearing, Cochlea, Tinnitus, Genetics
Health Sciences
Hemodynamic Monitoring and Therapy
Health Sciences
HIV/AIDS drug development and treatment
Health Sciences
HIV/AIDS Research and Interventions
Health Sciences
Hydrogen's biological and therapeutic effects
Health Sciences
Kawasaki Disease and Coronary Complications
Health Sciences
Malaria Research and Control
Health Sciences
Neonatal Health and Biochemistry
Health Sciences
Pancreatic and Hepatic Oncology Research
Life Sciences
Parasites and Host Interactions
Health Sciences
Patient Satisfaction in Healthcare
Health Sciences
Pediatric Urology and Nephrology Studies
Physical Sciences
Per- and polyfluoroalkyl substances research
Health Sciences
Pharmaceutical studies and practices
Health Sciences
Pharmacological Effects and Toxicity Studies
Health Sciences
Renal Diseases and Glomerulopathies
Health Sciences
Tissue Engineering and Regenerative Medicine
Health Sciences
Tuberculosis Research and Epidemiology
Life Sciences
Urban Agriculture and Sustainability
Health Sciences
Urological Disorders and Treatments
Social Sciences
Vaccine Coverage and Hesitancy
Publications (99)
Changes in caregiver psychosocial factors known to affect pediatric HIV disclosure: the Sankofa clinical trial experience in Ghana (2013–2023)
Scale-up of a paediatric HIV disclosure intervention in Ghana using a stepped wedge cluster randomised trial design: Sankofa 2 protocol and implementation
Open AccessTenofovir diphosphate concentrations in dried blood spots predict future HIV suppression but not virologic failure in adolescents with HIV
Investigating Household Water Quality Concerns in Kumasi, Ghana: Health Risks and Potential Implications: A Case Study
Evaluating intravascular hypovolaemia by manually assessing peripheral limb coolness compared with the capillary refill time in children aged <5 years in a tropical environment: a prospective cohort study of diagnostic accuracy
Pediatric kidney replacement therapies in low-to-middle income countries: a review and white paper
Pharmacokinetics of Tenofovir Diphosphate, Lamivudine Triphosphate and Emtricitabine Triphosphate in Adolescents With HIV Infection With and Without Tuberculosis Coinfection
The impact of deportation and disparities on pediatric kidney health: a humanitarian call to action
Open AccessDetect early, protect kidney health: World Kidney Day 2025
Disaster preparedness and kidney health in children
<i>APOL1</i> Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans
Open AccessStructures, Organization, and Delivery of Kidney Care to Children Living in Low-Resource Settings
Open AccessWCN24-1142 AN UNUSUAL CAUSE OF NEUROGENIC BLADDER IN A CHILD
Open AccessWCN24-1361 COMPLETE PENOSCROTAL TRANSPOSITION AND ASSOCIATED ANOMALIES IN A NEWBORN
Open AccessThe Africa hepatopancreatobiliary cancer consortium for the study of epidemiology, etiology, pathobiology of liver, biliary tract, and pancreatic cancers in Africa
Effect of HIV infection on plasma exposure to first-line TB drugs and target attainment in children
Global Dialysis Perspective: Ghana
Open AccessPediatric HIV Disclosure Intervention Improves Immunologic Outcome at 48 Weeks: The Sankofa Trial Experience
Open AccessPublic Health Implications of Household Water Sources in the Kumasi Metropolis, Ghana. A Case Study
Open AccessAdequacy of WHO weight-band dosing and fixed-dose combinations for the treatment of TB in children
Pediatric nephrology in under-resourced areas: one pill will not cure all ills—economics and awareness are both important factors
Open AccessPharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg
Open AccessHydrogen Sulfide as a Potential Therapy for COVID-19-Associated Nephropathy
Urine-Based Detection of Biomarkers Indicative of Chronic Kidney Disease in a Patient Cohort from Ghana
Open AccessContents
Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis
Open AccessUrine-based detection of biomarkers indicative of chronic kidney disease in a patient cohort from Ghana
Open AccessAssociation of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study
Open AccessDemography and Outcomes of End-Stage Renal Diseases (ESRD) of in Children Admitted to a Renal Unit in a Teaching Hospital in Kumasi, Ghana.
Open AccessTowards SDG3: Empowering Non-Nephrologists to Perform Peritoneal Dialysis in District Settings
Open AccessRenal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy
Open AccessGlobal Estimates and Determinants of Antituberculosis Drug Pharmacokinetics in Children and Adolescents: A Systematic Review and Individual Patient Data Meta-Analysis
Open AccessAssociation of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study
Open AccessISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics)
Open AccessA typical Kawasaki syndrome in COVID-19 infection: a case report of a multisystem inflammatory syndrome in a child (MIS-C)
Open AccessReply to: Observations on malnutrition and anti-TB drugs in Ghana
HIV Viremia Is Associated With APOL1 Variants and Reduced JC-Viruria
Open AccessAcute Kidney Injury in Children: A 3-Year Retrospective Analysis at Komfo Anokye Teaching Hospital, Ghana
Paediatric nephrology in under-resourced areas
Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection
Open AccessHearing Loss in Chronic Kidney Disease
Open AccessISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics)
Open AccessEffect of malnutrition on the pharmacokinetics of anti-TB drugs in Ghanaian children
Open AccessClean water to prevent kidney disease
Sankofa pediatric HIV disclosure intervention did not worsen depression scores in children living with HIV and their caregivers in Ghana
Open AccessSankofa Pediatric HIV Disclosure Intervention Did Not Worsen Depression Scores in Children Living with HIV and their Caregivers in Ghana
Open AccessSankofa Pediatric HIV Disclosure Intervention Did Not Worsen Depression Scores in Children Living with HIV and their Caregivers in Ghana
Open AccessManagement of idiopathic childhood nephrotic syndrome in sub-Saharan Africa: Ibadan consensus statement
Open AccessSankofa Pediatric HIV Disclosure Intervention Did Not Worsen Depression Scores in Children Living with HIV and their Caregivers in Ghana
Open AccessIllness Narratives of Children Living with HIV Who Do Not Know Their HIV Status in Ghana: I’m Sick, But I Don’t Know the Sickness—A Qualitative Study
Open AccessClinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana
Open AccessHearing loss in patients with chronic kidney disease and psychological burden in their caregivers
Open AccessAssociation Between Perfluoroalkyl Substance Exposure and Renal Function in Children With CKD Enrolled in H3Africa Kidney Disease Research Network
Open AccessEffect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old
Open AccessPopulation pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing
Open AccessEffect of Rifampin-Isoniazid-Containing Antituberculosis Therapy on Efavirenz Pharmacokinetics in HIV-Infected Children 3 to 14 Years Old
Open AccessPrevalence and correlates of depression among caregivers of children living with HIV in Ghana: findings from the Sankofa pediatric disclosure study
High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Open AccessEvaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations
Open AccessThe geographical distribution of dialysis services in Ghana
Open AccessBlood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana
Open AccessEffect of Genetic Variation of <i>NAT2</i> on Isoniazid and <i>SLCO1B1</i> and <i>CES2</i> on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis
Open AccessEvaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children
Open AccessPeritoneal Dialysis to Treat Patients with Acute Kidney Injury—The Saving Young Lives Experience in West Africa: Proceedings of the Saving Young Lives Session at the First International Conference of Dialysis in West Africa, Dakar, Senegal, December 2015
Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection
Open AccessThe role of nutritional status on follow-up among HIV-infected children at a teaching hospital clinic in Ghana
Open AccessTopic: Acute Kidney Injury in Children: 3-Year Data Review from Ghana
Open AccessQuality of life among Ghanaian adolescents living with perinatally acquired HIV: a mixed methods study
Open AccessHIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status
Open AccessSankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality
Open AccessSANKOFA
Open AccessPharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection
Open AccessThe unacknowledged impact of urinary schistosomiasis in children: 5 cases from Kumasi, Ghana
Open AccessTitle Page / Table of Contents
State of Renal Replacement Therapy Services in Ghana
Open AccessAnnual Congress of the Chinese Blood Purification Center Administration Committee. September 25-28, 2014, Guangzhou: Abstracts
Open AccessPelvi-Ureteric Junction Obstruction at Red Cross Children's Hospital, Cape Town: a Six Year Review.
2014Pediatric Urology and Nephrology Studies
HIV infection in severely malnourished children in Kumasi, Ghana: a cross-sectional prospective study
Open AccessFront & Back Matter
Open AccessTitle Page / Table of Contents
Open AccessPeritoneal Dialysis as a Mode of Treatment for Acute Kidney Injury in Sub-Saharan Africa
Open AccessAcknowledgement to the Reviewers
Open AccessGenome-wide association study indicates two novel resistance loci for severe malaria
Errata
Open AccessAssessment and Management of Severe Malnutrition in Children
Open AccessT Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children
Open AccessPaediatric tuberculosis at the national teaching hospital CNHU-HKM of Cotonou, Benin: a retrospective study.
2011Tuberculosis Research and Epidemiology
Assessment and Management of Severe Malnutrition in Children Evaluation Et Gestion De La Malnutrition Chez Les Enfants
2011Child Nutrition and Water Access
Correction: Randomized Controlled Trial of RTS,S/AS02<sub>D</sub>and RTS,S/AS01<sub>E</sub>Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children
Open AccessAssessment of GFR by four methods in adults in Ashanti, Ghana: the need for an eGFR equation for lean African populations
Open AccessRandomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children
Open AccessMalnutrition: Missed opportunities for diagnosis
Open AccessAudit of posterior urethral valve (PUV) in children at Red Cross Children Hospital, Cape Town, January 2002 - January 2009
Open Access2009Urological Disorders and Treatments
Urine dipstick as a screening test for urinary tract infection
Capillary refill time as an independent prognostic indicator in severe and complicated malaria
Rural and semi-urban differences in salt intake, and its dietary sources, in Ashanti, West Africa.
2005Child Nutrition and Water Access
RURAL AND SEMI-URBAN DIFFERENCES IN SALT INTAKE, AND ITS DIETARY SOURCES,
2005Urban Agriculture and Sustainability
PREVALENCE, DETECTION, MANAGEMENT AND CONTROL OF HYPERTENSION IN ASHANTI, WEST AFRICA
Academic Metrics
DepartmentDepartment of Child Health
Total Publications99
Research Themes37
Open Access Papers69
Department of Child Health
Kwame Nkrumah University of Science and Technology