Michael Ntim
The researcher's work is centered on integrating biological biomarkers across various domains to develop effective strategies for cancer immunotherapy, health disparities, and chronic disease management. Their research spans multiple fields, including immunology, neuroscience, pharmacology, and public health, with a focus on understanding the role of biological markers in disease diagnosis, treatment, and prevention. Key themes include: 1. **Cancer Immunotherapy and Biomarkers**: Development of models like the immune score to predict prognosis using biomarkers. 2. **Biology and Health Disparities**: Investigating interactions between chronic diseases (e.g., hypertension) and factors affecting brain development. 3. **Neurogenesis and Ageing**: Exploring the role of neural connections in cognitive decline, supported by neurovascular insights. 4. **Global Health Policies and Public Health**: Considering interventions like task-shifting strategies to reduce hypertension. 5. **Autophagy and Pancreatic Cancer**: Addressing both promising benefits and potential controversies regarding autophagy's role in cancer. 6. **Neuroscience and Sleep Disorders**: Linking sleep patterns with brain health, influencing long-term cognitive outcomes. The researcher employs a holistic approach, using biomarkers as tools to enhance understanding and improve treatment options across these interconnected fields, aiming to contribute significantly to global health solutions.
Alzheimer's disease research and treatments
Autophagy in Disease and Therapy
Blood Pressure and Hypertension Studies
Cancer Immunotherapy and Biomarkers
Cancer-related molecular mechanisms research
Chemokine receptors and signaling
Epigenetics and DNA Methylation
Genetics, Aging, and Longevity in Model Organisms
Global Maternal and Child Health
Global Public Health Policies and Epidemiology
Gut microbiota and health
Health disparities and outcomes
Health Systems, Economic Evaluations, Quality of Life
Ion Transport and Channel Regulation
Maternal Mental Health During Pregnancy and Postpartum
Metabolism, Diabetes, and Cancer
Nausea and vomiting management
Neonatal and Maternal Infections
Neurogenesis and neuroplasticity mechanisms
Neurological Disease Mechanisms and Treatments
Neuroscience and Neuropharmacology Research
Pancreatic and Hepatic Oncology Research
Pancreatitis Pathology and Treatment
Proteoglycans and glycosaminoglycans research
Receptor Mechanisms and Signaling
Stress Responses and Cortisol
DNA methylation as a new frontier in treating fear-related disorders: A need for careful evaluation
Open AccessPredictors of postpartum depression among new mothers in Kumasi, Ghana: A multicenter study using Bayesian analysis
Open AccessTriglyceride-glucose index in predicting gastric cancer prognosis: A need for caution
Open AccessEditorial: Neurovascular health insights: a powerful tool to understand and prognose neurocognitive decline
Open AccessPhospholipase D2: A biomarker for stratifying disease severity in acute pancreatitis?
Open AccessCell-type-specific expression of Nav1.6 in the developing brain of mice and its involvement in glial activation in Alzheimer’s disease
Review of: "Auditing the Cost of Treating Hypertension in a Tertiary Health Facility in Yobe State, North-Eastern Nigeria"
Open AccessDeveloping Culturally Salient Assessment Tools and Interventions for Underserved and High-Risk Populations in the United States and Africa
TIP60 mediates stress-induced hypertension via promoting glutamate <sup>dmPFC-</sup> <sup>to-</sup> <sup>vCA1</sup> release
Open AccessAQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized Expression of AQP4 Protein in Astrocytic Endfeet at the Blood–Brain Barrier
Open AccessBacteriological Profile and Predictors of Death Among Neonates With Blood Culture-Proven Sepsis in a National Hospital in Tanzania—A Retrospective Cohort Study
Open AccessReducing Nav1.6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription
Open AccessLong-Term Social Isolation-Induced Autophagy Inhibition and Cell Senescence Aggravate Cognitive Impairment in D(+)Galactose-Treated Male Mice
Open AccessTwo-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice
TIP60 buffers acute stress response and depressive behaviour by controlling PPARγ-mediated transcription
Prediction of Survival Rate and Chemotherapy Effect by an Immune Score Model in Colorectal Cancer
Open AccessSRC-1 Deficiency Increases Susceptibility of Mice to Depressive-Like Behavior After Exposure to CUMS
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway
Open AccessEffect of emodin on long non‐coding RNA‐mRNA networks in rats with severe acute pancreatitis‐induced acute lung injury
Open AccessTreatment with <i>Bifidobacteria</i> can suppress Aβ accumulation and neuroinflammation in APP/PS1 mice
Open AccessGPR50 Distribution in the Mouse Cortex and Hippocampus
SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice
Open AccessThe landscape of immune cell infiltration and its clinical implications of pancreatic ductal adenocarcinoma
Open AccessTRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway
Application of the Consolidated Framework for Implementation Research to examine nurses’ perception of the task shifting strategy for hypertension control trial in Ghana
Open AccessAn immune cell infiltration-based immune score model predicts prognosis and chemotherapy effects in breast cancer
Open AccessSub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section — a randomized control trial
Open AccessImpaired Cognitive Function and Altered Hippocampal Synaptic Plasticity in Mice Lacking Dermatan Sulfotransferase Chst14/D4st1
Open AccessLong-term social isolation inhibits autophagy activation, induces postsynaptic dysfunctions and impairs spatial memory
IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes
Health insurance coverage with or without a nurse-led task shifting strategy for hypertension control: A pragmatic cluster randomized trial in Ghana
Open AccessIssue Information ‐ TOC
Open Access[LB.03.07] COMPARATIVE EFFECTIVENESS CLUSTER-RANDOMIZED TRIAL OF A NURSE-LED TASK-SHIFTING STRATEGY FOR HYPERTENSION CONTROL VERSUS PROVISION OF HEALTH INSURANCE COVERAGE IN CHCS IN GHANA
‘I believe high blood pressure can kill me:’ using the PEN-3 Cultural Model to understand patients’ perceptions of an intervention to control hypertension in Ghana
Sustaining Nurse‐Led Task‐Shifting Strategies for Hypertension Control: A Concept Mapping Study to Inform Evidence‐Based Practice
Erratum to: Training nurses in task-shifting strategies for the management and control of hypertension in Ghana: a mixed-methods study
Open AccessExploring stakeholders’ perceptions of a task-shifting strategy for hypertension control in Ghana: a qualitative study
Open AccessTraining nurses in task-shifting strategies for the management and control of hypertension in Ghana: a mixed-methods study
Open AccessOC05_01 Task-Shifting for the Management of Hypertension: Lessons From the Global Alliance for Chronic Diseases
A cluster-randomized trial of task shifting and blood pressure control in Ghana: study protocol
Open AccessDepartment of Physiology
Kwame Nkrumah University of Science and Technology