Paul Buule

Paul Buule

10 Publications1 Research Theme10 Open Access
Research Overview & Focus

This researcher focuses on advancing HIV-1 research within the life sciences domain, particularly examining treatment efficacy and immune correlates in viral dynamics. Their work explores themes of latency reversal, integrase inhibitor effects, and reservoir formation among HIV-1-infected individuals, with applications to public health strategies.

Key Research Themes (1)
Life Sciences

HIV Research and Treatment

Publications (10)

Association between HIV-1 Nef-mediated MHC-I downregulation and the maintenance of the replication-competent latent viral reservoir in individuals with virally suppressed HIV-1 in Uganda: an exploratory cohort study

Open Access
2025HIV Research and TreatmentDOI: 10.1016/j.lanmic.2024.101018

PP1.11 – 00021 Impact of HIV-1 Tat and TAR Sequence Diversity on Clinical and Reservoir Characteristics

Open Access
2024HIV Research and TreatmentDOI: 10.1016/j.jve.2024.100460

HIV-1 subtype A1, D, and recombinant proviral genome landscapes during long-term suppressive therapy

Open Access
2024HIV Research and TreatmentDOI: 10.1038/s41467-024-48985-9

Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen

Open Access
2024HIV Research and TreatmentDOI: 10.1016/j.ebiom.2024.105040

Effective and targeted latency reversal in CD4 <sup>+</sup> T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection

Open Access
2024HIV Research and TreatmentDOI: 10.1080/22221751.2024.2327371

Dating reservoir formation in virologically suppressed people living with HIV-1 in Rakai, Uganda

Open Access
2023HIV Research and TreatmentDOI: 10.1093/ve/vead046

Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen

Open Access
2023HIV Research and TreatmentDOI: 10.1101/2023.05.12.23289896

PP 1.30 – 00159 Dating HIV-1 reservoir formation in ARV-suppressed Ugandans

Open Access
2022HIV Research and TreatmentDOI: 10.1016/j.jve.2022.100134

Reduced HIV-1 latent reservoir outgrowth and distinct immune correlates among women in Rakai, Uganda

Open Access
2020HIV Research and TreatmentDOI: 10.1172/jci.insight.139287

Reduced Frequency of Cells Latently Infected With Replication-Competent Human Immunodeficiency Virus-1 in Virally Suppressed Individuals Living in Rakai, Uganda

Open Access
2017HIV Research and TreatmentDOI: 10.1093/cid/cix478
Academic Metrics
DepartmentDepartment of Civil Engineering
Total Publications10
Research Themes1
Open Access Papers10

Department of Civil Engineering

Kwame Nkrumah University of Science and Technology

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