Samuel Oppong Bekoe
Department of Pharmaceutical ChemistryHealth SciencesPhysical SciencesLife Sciences

Samuel Oppong Bekoe

40 Publications27 Research Themes25 Open Access
Research Overview & Focus

The researcher's work focuses primarily on the role of pharmaceuticals and their bioactive compounds in health sciences and life sciences. Their studies span themes including the monitoring of antacids and pesticides, antibiotic use and resistance, phenodynamic and pharmacogenetic aspects of plant medicine, analytical methods for drug residue assessment, and its impact on human health and environmental impacts. Key findings include advancements in identifying pharmacophore motifs in plants, rigorous methodologies for analyzing compound bioactivity and pharmacophores, and innovations in assessing antiparasitic residues in herbal products.

Faculty Biography

I was born and brought up in Koforidua, Eastern region, Ghana. Belong to a family of of six with my parents, me and my younger brother and two big sisters. Had my secondary eductaion at Ofori Panin  and Pope John secondary school respectively for my ordinary and advanced level. I enjoy Extra-curricular activities like sports, travelling, crafts, etc. I trained as a pharmacist for my Bachelor degree and now a teacher at the Kwame Nkrumah University of Science and Technology.

Key Research Themes (27)
Health Sciences

Adrenal Hormones and Disorders

Physical Sciences

Analytical Chemistry and Chromatography

Physical Sciences

Analytical Methods in Pharmaceuticals

Life Sciences

Antibiotic Use and Resistance

Health Sciences

Antimicrobial Resistance in Staphylococcus

Life Sciences

Bioactive natural compounds

Life Sciences

Biosimilars and Bioanalytical Methods

Life Sciences

Drug-Induced Hepatotoxicity and Protection

Physical Sciences

Effects and risks of endocrine disrupting chemicals

Life Sciences

Ethnobotanical and Medicinal Plants Studies

Health Sciences

Gastrointestinal motility and disorders

Health Sciences

Helminth infection and control

Health Sciences

Hepatitis C virus research

Physical Sciences

Matrix Theory and Algorithms

Life Sciences

Microbial infections and disease research

Life Sciences

Natural product bioactivities and synthesis

Life Sciences

Pesticide Residue Analysis and Safety

Physical Sciences

Pharmaceutical and Antibiotic Environmental Impacts

Health Sciences

Pharmaceutical Quality and Counterfeiting

Life Sciences

Phytochemistry and Bioactivity Studies

Life Sciences

Phytochemistry and Biological Activities

Life Sciences

Phytochemistry and biological activity of medicinal plants

Life Sciences

Phytochemistry Medicinal Plant Applications

Life Sciences

Plant Pathogens and Fungal Diseases

Life Sciences

Sensory Analysis and Statistical Methods

Life Sciences

Synthesis and bioactivity of alkaloids

Life Sciences

Traditional and Medicinal Uses of Annonaceae

Publications (40)

The Effect of Storage Time on the Levels of Phthalates in Extemporaneous Preparations in Ghana

Open Access
2024Effects and risks of endocrine disrupting chemicalsDOI: 10.21203/rs.3.rs-4572478/v1

Development and Validation of an RP-HPLC Method for the Quantitative Analysis of Triclosan in Human Urine

Open Access
2023Analytical Chemistry and ChromatographyDOI: 10.1155/2023/6684834

Towards the development of analytical monograph specifications for the quality assessment of the medicinal plant Phyllanthus urinaria

2023Phytochemistry and Bioactivity StudiesDOI: 10.1016/j.phytochem.2023.113854

Prevalence of Hepatitis C at a Primary Hospital in the Western Region of Ghana

Open Access
2023Hepatitis C virus researchDOI: 10.12691/ajidm-11-1-2

Bioequivalence studies of cetirizine tablets using the urine excretion data of healthy Ghanaian male volunteers

Open Access
2023Biosimilars and Bioanalytical MethodsDOI: 10.1016/j.heliyon.2022.e12665

Antimalarial Properties of <i>Sida cordifolia</i> L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression

Open Access
2023Ethnobotanical and Medicinal Plants StudiesDOI: 10.1155/2023/5560711

Anthelmintic Agents from African Medicinal Plants: Review and Prospects

Open Access
2022Helminth infection and controlDOI: 10.1155/2022/8023866

Development of an Analytical Workflow to Support the Establishment of Monographs in African Pharmacopoeias – Combretum mucronatum Leaves as Example

2022Ethnobotanical and Medicinal Plants StudiesDOI: 10.1055/a-2002-2260

Short Lecture 5 “Analytical investigations reveal challenges with the collection of Combretum mucronatum (Schumach. &amp; Thonn.) leaves for herbal medicine purposes in Ghana”

2022Ethnobotanical and Medicinal Plants StudiesDOI: 10.1055/s-0042-1758901

HPLC-HRESI-MSn Characterization of Polyphenolic Compounds in the Stem Bark of Chlorophora regia A. Chev (Moraceae)

Open Access
2022Bioactive natural compoundsDOI: 10.25026/jtpc.v6i2.419

Quality assessment of African herbal medicine: A systematic review and the way forward

2022Ethnobotanical and Medicinal Plants StudiesDOI: 10.1016/j.fitote.2022.105287

The Unethical Use of Paracetamol As a Food Tenderizer in Four SelectedAfrican Countries: A Major Public Health Concern?

2022Drug-Induced Hepatotoxicity and ProtectionDOI: 10.2174/2949681015666220810125820

Development and Validation of an Ion-Pair HPLC-UV Method for the Quantitation of Quinoline and Indoloquinoline Alkaloids in Herbal and Pharmaceutical Antimalarial Formulations

Open Access
2022Synthesis and bioactivity of alkaloidsDOI: 10.1155/2022/4625954

Chromatographic method development for the simultaneous assay of pseudoephedrine hydrochloride and chlorphenamine maleate in oral dosage formulations

Open Access
2022Analytical Methods in PharmaceuticalsDOI: 10.1016/j.sciaf.2022.e01109

Reservoir of Antibiotic Residues and Resistant Coagulase Negative Staphylococci in a Healthy Population in the Greater Accra Region, Ghana

Open Access
2022Antimicrobial Resistance in StaphylococcusDOI: 10.3390/antibiotics11010119

Analytical Techniques for Therapeutic Drug Monitoring and Clinical Toxicology

2022Analytical Methods in PharmaceuticalsDOI: 10.1007/978-3-031-12398-6_2

Quality Assurance of Samples for Therapeutic Drug Monitoring and Clinical Toxicology

2022Biosimilars and Bioanalytical MethodsDOI: 10.1007/978-3-031-12398-6_10

Fruits of Vitex doniana sweet: toxicity profile, anti-inflammatory and antioxidant activities, and quantification of one of its bioactive constituents oleanolic acid

Open Access
2021Natural product bioactivities and synthesisDOI: 10.1016/j.heliyon.2021.e07910

Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.

Open Access
2021Traditional and Medicinal Uses of AnnonaceaeDOI: 10.1155/2021/2852442

Monitoring and risk assessment of pesticide residues in selected herbal medicinal products in Ghana

2021Pesticide Residue Analysis and SafetyDOI: 10.1007/s10661-021-09261-1

Bioequivalence Study of Locally Manufactured Cetirizine Tablets in Ghana

Open Access
2021Biosimilars and Bioanalytical MethodsDOI: 10.17632/s4wfx5xrk3.1

Fruits of &lt;i&gt;Vitex Doniana&lt;/i&gt; Sweet: Toxicity Profile, Anti-Inflammatory and Antioxidant Activities, and Quantification of One of its Bioactive Constituents Oleanolic Acid

Open Access
2021Natural product bioactivities and synthesisDOI: 10.2139/ssrn.3867114

Correction to: Detection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method

Open Access
2020Pharmaceutical Quality and CounterfeitingDOI: 10.1007/s42452-020-03806-8

<i>Libkrylov</i>: A modular open-source software library for extremely large and dense eigenvalue and linear problems

2020Matrix Theory and AlgorithmsDOI: 10.1021/scimeetings.0c07150

Detection and quantification of antibiotic residues in urine samples of healthy individuals from rural and urban communities in Ghana using a validated SPE-LC-MS/MS method

Open Access
2020Pesticide Residue Analysis and SafetyDOI: 10.1007/s42452-020-03742-7

Exposure of consumers to substandard antibiotics from selected authorised and unauthorised medicine sales outlets in Ghana

Open Access
2020Pharmaceutical Quality and CounterfeitingDOI: 10.1111/tmi.13442

Evaluation of acid neutralizing and buffering capacities of selected antacids in Ghana

Open Access
2020Sensory Analysis and Statistical MethodsDOI: 10.1016/j.sciaf.2020.e00347

Prologue: Veterinary Pharmaceuticals

Open Access
2020Pharmaceutical and Antibiotic Environmental ImpactsDOI: 10.5772/intechopen.89902

CHARACTERIZATION AND RP-HPLC METHOD DEVELOPMENT OF A BIOMARKER (BERGENIN) FROM THE ROOTS OF Securinega virosa

2019Phytochemistry and Bioactivity Studies

MALDI–HRMS imaging and HPLC–HRESI–MS<sup><i>n</i></sup> characterisation of kaurane diterpenes in the fruits of <scp><i>Xylopia aethiopica</i></scp> (Dunal) A. Rich (Annonaceae)

2019Traditional and Medicinal Uses of AnnonaceaeDOI: 10.1002/pca.2901

Veterinary Medicine and Pharmaceuticals

Open Access
2019Microbial infections and disease researchDOI: 10.5772/intechopen.79335

In Vitro Evaluation of Cocoa Pod Husk Pectin as a Carrier for Chronodelivery of Hydrocortisone Intended for Adrenal Insufficiency

Open Access
2017Gastrointestinal motility and disordersDOI: 10.1155/2017/8284025

Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations

Open Access
2017Adrenal Hormones and DisordersDOI: 10.1155/2017/9495732

Medicinal Plants and Natural Products with Demonstrated Wound Healing Properties

Open Access
2016Phytochemistry Medicinal Plant ApplicationsDOI: 10.5772/63574

Pharmaceutical Residues Affecting the UNESCO Biosphere Reserve Kristianstads Vattenrike Wetlands: Sources and Sinks

Open Access
2016Pharmaceutical and Antibiotic Environmental ImpactsDOI: 10.1007/s00244-016-0303-7

Pharmacognostic studies of the leaves and seeds of Cassia occidentalis (Linn.) (Leguminosae)

2016Phytochemistry and biological activity of medicinal plants

Cytotoxicity of the Aqueous Extract of Clerodendrum splendens on HaCaT Keratinocytes

2016Phytochemistry and Biological ActivitiesDOI: 10.9734/ejmp/2016/27067

Effect of the aqueous leaves extract of Clerodendron splendens on physiology of HaCaT keratinocytes

2015Plant Pathogens and Fungal DiseasesDOI: 10.1055/s-0035-1565500

Antibiotic Exposure in a Low-Income Country: Screening Urine Samples for Presence of Antibiotics and Antibiotic Resistance in Coagulase Negative Staphylococcal Contaminants

Open Access
2014Antibiotic Use and ResistanceDOI: 10.1371/journal.pone.0113055

Determination of thirteen antibiotics in drug products – A new LC-MS/MS tool for screening drug product quality

2014Pharmaceutical Quality and CounterfeitingDOI: 10.1039/c4ay00748d
Academic Metrics
DepartmentDepartment of Pharmaceutical Chemistry
Total Publications40
Research Themes27
Open Access Papers25

Department of Pharmaceutical Chemistry

Kwame Nkrumah University of Science and Technology

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