Michael Frimpong
The researcher has made significant contributions to health sciences through advancements in diagnostics, therapeutic interventions, and public health practices. They have developed novel rapid detection methods for infectious diseases, such as Mycobacterium ulcerans, SARS-CoV-2, and Salmonella enterica, improving clinical accuracy and efficiency. Their work on TB epidemiology has provided insights into multidrug-resistant bacteria, while their research on parasitic infections, particularly Schistosoma haematobium, has advanced understanding of neglected tropical diseases. The researcher’s focus on innovative methodologies, such as real-time recombinase polymerase amplification assays and rapid PCR tests, demonstrates a commitment to precision in detecting and managing life-threatening health conditions. Their global reach in sub-Saharan Africa underscores their dedication to addressing the healthcare needs of marginalized communities. By integrating biological technologies with clinical practices, they have significantly improved outcomes for public health, particularly in regions like Ghana where challenges remain prevalent.
Faculty Biography
My academic training and research experience have provided me with an excellent background in multiple biological disciplines including molecular biology, microbiology, biochemistry, genetics and immunology. I am passionate about becoming one of the increasing number of “home grown” world class researchers that are able to address pressing questions in Africa. I developed interest in NTDs with a focus on Buruli ulcer (BUD) in 2008 when together with colleagues from KCCR in collaboration with the Department of infectious Diseases and Tropical Medicine (DITM, University of Munich, Germany), I worked on developing methods for early diagnosis, the investigation of social and economic impact of BUD. In 2011, I enrolled for my PhD with support from the BURULIVAC project which gave me invaluable hands-on experience in immunology, molecular biology and microbiology. In 2017, I successfully competed for the EDCTP Career Development Fellowship with which developed a rapid diagnostic assay on a mobile laboratory platform capable of diagnosing BUD at the point of patient care. Currently my group is evaluating this testing approach in two treatment centres in Ghana. I believe that I can contribute to and drive forward innovative research answering local needs by establishing a collaborative research program of diagnostic, microbiologic and genomic excellence in neglected tropical diseases (NTDs). Such research is essential for good policy making and ultimately for better health outcomes.
Air Quality and Health Impacts
Biosensors and Analytical Detection
Clinical Laboratory Practices and Quality Control
Dermatological diseases and infestations
Inflammatory Biomarkers in Disease Prognosis
Innovative Teaching Methods
Malaria Research and Control
Mycobacterium research and diagnosis
Parasites and Host Interactions
Platelet Disorders and Treatments
Risk Management in Financial Firms
Salmonella and Campylobacter epidemiology
SARS-CoV-2 and COVID-19 Research
SARS-CoV-2 detection and testing
Syphilis Diagnosis and Treatment
Tuberculosis Research and Epidemiology
Vibrio bacteria research studies
Zoonotic diseases and public health
Clinical epidemiology of Buruli ulcer disease in Ghana, 2006–2024
The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers
Open AccessThe microbiome of Total Suspended Particles (TSP) and its influence on the respiratory microbiome of healthy office workers
Open AccessImplementation of an integrated control programme for neglected tropical diseases of the skin in Ghana: The essential role of the laboratory
Open AccessRapid Identification of Bacterial Composition in Wastewater by Combining Reverse Purification Nucleic Acid Extraction and Nanopore Sequencing
Open AccessClinical and microbiological predictors of healing in Buruli ulcer disease
Open AccessDifferences in PPD- and mitogen-induced T-cell activation marker expression characterize immunopathology in acute tuberculosis patients
Open AccessAn African One Health network for antimicrobial resistance and neglected tropical diseases
A single synthetic lipid antigen for improved serological diagnosis of Buruli ulcer
Open AccessPA-706 Clinical and microbiological predictors of healing in Buruli ulcer disease
Open AccessPA-274 Lessons learned from a phase 2 diagnostic clinical trial in seven Sub-Saharan African countries
Open AccessOA-322 Bridging the research gaps on AMR in sub-Saharan Africa – A one health approach
Open AccessEvaluation of a real-time recombinase polymerase amplification assay for rapid detection of Schistosoma haematobium infection in a resource-limited setting
Open AccessMulti-centric evaluation of Biomeme Franklin Mobile qPCR for rapid detection of Mycobacterium ulcerans in clinical specimens
Open AccessA multi-country phase 2 study to evaluate the suitcase lab for rapid detection of SARS-CoV-2 in seven Sub-Saharan African countries: Lessons from the field
Open AccessMulti-centric evaluation of Biomeme Franklin Mobile qPCR for rapid detection of<i>Mycobacterium ulcerans</i>in clinical specimens
Open AccessA combined effort of 11 laboratories in the WHO African region to improve quality of Buruli ulcer PCR diagnosis: The “BU-LABNET”
Open AccessDiagnostics to support the eradication of yaws—Development of two target product profiles
Open AccessDiagnostics to support the eradication of yaws – Development of Two Target Product Profiles
Open AccessMental health and quality of life burden in Buruli ulcer disease patients in Ghana
Open AccessCaregiver burden in Buruli ulcer disease: Evidence from Ghana
Open AccessLow risk of SARS-CoV-2 in blood transfusion
Open AccessCo-infection of HIV in patients with Buruli ulcer disease in Central Ghana
Open AccessTransmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing
Open AccessMapping suitability for Buruli ulcer at fine spatial scales across Africa: A modelling study
Open AccessEvaluation of a real-time recombinase polymerase amplification assay for rapid detection of Schistosoma haematobium infection in resource-limited setting
Suitcase Lab for Rapid Detection of SARS-CoV-2 Based on Recombinase Polymerase Amplification Assay
Open AccessDiagnostics for COVID-19: A case for field-deployable, rapid molecular tests for community surveillance
Open AccessA scabies outbreak in the North East Region of Ghana: The necessity for prompt intervention
Open AccessMultiplex Recombinase Polymerase Amplification Assay for Simultaneous Detection of Treponema pallidum and Haemophilus ducreyi in Yaws-Like Lesions
Open AccessTransmission of SARS-CoV-2 in Northern Ghana; Insights from Whole Genome Sequencing
Open AccessMultiplex Recombinase Polymerase Amplification Assay for Simultaneous Detection of Treponema pallidum and Haemophilus ducreyi in yaws-like lesions
Open AccessBarriers to Buruli ulcer treatment completion in the Ashanti and Central Regions, Ghana
Open AccessMapping suitability for Buruli ulcer at fine spatial scales across Africa: a modelling study
Open AccessAssessment of platelet indices and platelet activation markers in children with Plasmodium falciparum malaria
Open AccessRifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial
Open AccessRapid Extraction Method of Mycobacterium ulcerans DNA from Clinical Samples of Suspected Buruli Ulcer Patients
Open AccessInter-Laboratory Comparability of Clinical Chemistry Testing: A New Perspective
Buruli ulcer treatment: Rate of surgical intervention differs highly between treatment centers in West Africa
Open AccessParadoxical reactions in Buruli ulcer after initiation of antibiotic therapy: Relationship to bacterial load
Open AccessProviding insight into the incubation period of Mycobacterium ulcerans disease: two case reports
Open AccessExpression of platelet parameters and platelet membrane glycoproteins in childhood Burkitt lymphoma
Mapping the global distribution of Buruli ulcer: a systematic review with evidence consensus
Open AccessOC 8173 RAPID DETECTION OF <i>MYCOBACTERIUM ULCERANS</i> BY RECOMBINASE POLYMERASE AMPLIFICATION
Open AccessRapid detection of Mycobacterium ulcerans with isothermal recombinase polymerase amplification assay
Open AccessRandomised Trial to Compare Clarithromycin (Extended Release)-Rifampicin and Streptomycin-Rifampicin for Early, Limited Lesions of <i>M. Ulcerans</i> Infection
Open AccessExpression of Platelet Parameters and Platelet Membrane Glycoproteins in Childhood Burkitt Lymphoma
Open AccessRecombinase polymerase amplification assay for detection of Mycobacterium ulcerans DNA v1
Open AccessIFN-γ and IL-5 whole blood response directed against mycolactone polyketide synthase domains in patients with<i>Mycobacterium ulcerans</i>infection
Open AccessCharacterization of Salmonella enterica from invasive bloodstream infections and water sources in rural Ghana
Open AccessOccurrences of Buruli ulcer infections in humans and Mycobacterium ulcerans in animal and environmental samples
Open AccessKey drivers of graduate students’ interest in the subject of immunology in a tertiary institution of Ghana
Open AccessMapping the Global Distribution of Buruli Ulcer Through a Systematic Review with an Evidence Consensus Approach
Open AccessClearance of viable Mycobacterium ulcerans from Buruli ulcer lesions during antibiotic treatment as determined by combined 16S rRNA reverse transcriptase /IS 2404 qPCR assay
Open AccessGraduate students’ interest in immunology as a discipline
Open AccessBuruli ulcer: wound care and rehabilitation
Open AccessHigh prevalence of multidrug-resistant tuberculosis among patients with rifampicin resistance using GeneXpert Mycobacterium tuberculosis/rifampicin in Ghana
Open AccessMetabolomic profiles delineate mycolactone signature in Buruli ulcer disease
Open AccessSimple, Rapid Mycobacterium ulcerans Disease Diagnosis from Clinical Samples by Fluorescence of Mycolactone on Thin Layer Chromatography
Open AccessLoop-Mediated Isothermal Amplification for Laboratory Confirmation of Buruli Ulcer Disease—Towards a Point-of-Care Test
Open AccessDrinking Water from Dug Wells in Rural Ghana — Salmonella Contamination, Environmental Factors, and Genotypes
Open AccessEffectiveness of Routine BCG Vaccination on Buruli Ulcer Disease: A Case-Control Study in the Democratic Republic of Congo, Ghana and Togo
Open AccessMicroscopy for Acid Fast Bacilli: A Useful but Neglected Tool in Routine Laboratory Diagnosis of Buruli Ulcer
Reply to “Compliance with Antimicrobial Therapy for Buruli Ulcer”
Open AccessA Severe Case of Buruli Ulcer Disease with Pleural Effusions
Open AccessCombined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease
Open AccessInfection with<i>Mansonella perstans</i>Nematodes in Buruli Ulcer Patients, Ghana
Open AccessTHE ROLE OF THE INTERNAL AUDIT FUNCTION IN PROMOTING EFFECTIVE AUDIT PRACTICES IN GHANA
Department of Molecular Medicine
Kwame Nkrumah University of Science and Technology