George Kwaw Ainooson
The researcher's work integrates comprehensive studies across various biological domains, focusing on understanding phytocannabinoid systems, mast cell signaling, neuroinflammation mechanisms, and anthocyanins in plants. Their research underscores the role of these components in both therapeutic applications and fundamental biological processes. Through systematic investigations, they have elucidated the pharmacological effects of natural compounds and explored their potential therapeutic uses across diverse health contexts, from inflammatory diseases to neurodegenerative conditions.
Faculty Biography
George Ainooson is an Associate Professor at the Department of Pharmacology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.He completed his Bachelor of Pharmacy (BPharm) and Master of Philosophy (MPhil. Pharmacology) degrees in the Faculty of Pharmacy and Pharmaceutical Sciences (FPPS), KNUST, in 2003 and 2007 respectively, and a PhD in Molecular Biology from the Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.He started his teaching and research career in 2007 as a lecturer in the Department of Pharmacology, KNUST, in natural product pharmacology, with a keen interest in inflammatory disorders. He served in this position for 5 years before his promotion to the rank of of a Senior Lecturer in 2013 and subsequent award of a DAAD scholarship in the same year for a PhD in Molecular Biology at the Institute of Toxicology and Genetics (ITG), now the Institute of Biological and Chemical Systems (IBCS) in the KIT.His PhD thesis titled 'Pest-Domain-Enriched Tyrosine Phosphatase and Glucocorticoids as Regulators of Mast Cell Signalling', sought to employ transcriptomics to deepen our understanding of the molecular mechanisms responsible for the beneficial and toxic effects of glucocorticoids, to facilitate the design of newer drugs with equipotent anti-inflammatory effect as glucocorticoids, but minimal toxic effects.Having trained in a steroid hormone lab that specialises in the molecular endocrinology of the steroid hormone pathway in anaphylaxis and hormone-dependent malignancy (prostate and breast cancer) at KIT and as a postdoctoral research fellow in Cancer Immunology at the Center for Medical Innovation, Nagasaki University, his current research work covers the use of rodent, zebrafish and cell-based models in elucidating the mechanism of natural products in inflammatory disorders and steroid hormone-dependent malignancies such as prostate cancer. Through his research work and headship period at the Department of Pharmacology, KNUST, he secured support from the GIZ and his alma mater KIT, to run molecular pharmacology and zebrafish labs at the KNUST.
Anorectal Disease Treatments and Outcomes
Asthma and respiratory diseases
Cannabis and Cannabinoid Research
Cytokine Signaling Pathways and Interactions
Ethnobotanical and Medicinal Plants Studies
Herbal Medicine Research Studies
Hibiscus Plant Research Studies
Hormonal and reproductive studies
Inflammatory Bowel Disease
Mast cells and histamine
Moringa oleifera research and applications
Natural Antidiabetic Agents Studies
Natural Compound Pharmacology Studies
Neuroinflammation and Neurodegeneration Mechanisms
Pharmacological Effects of Natural Compounds
Phytochemical compounds biological activities
Phytochemistry and Biological Activities
Phytochemistry and biological activities of Ficus species
Prostate Cancer Diagnosis and Treatment
T-cell and Retrovirus Studies
Tea Polyphenols and Effects
Trace Elements in Health
Traditional and Medicinal Uses of Annonaceae
Department of Pharmacology
Kwame Nkrumah University of Science and Technology