Bismarck Dinko

Bismarck Dinko

27 Publications1 Research Theme25 Open Access
Research Overview & Focus

The researcher has conducted extensive research on malaria detection, diagnosis, treatment, and control in Ghana. Their work focuses on identifying Plasmodium species after asymptomatic infections using various methods, characterizing their gene expression patterns within host cells, and developing diagnostic tools to prevent malaria in children less than five years old. The findings highlight the effectiveness of treatments like ACT (Asymptomatic Gibbs Reproductive Infection) in detecting specific malaria parasites and suggest that immune evasion mechanisms, such as cross-stage antigenic targeting, can be harnessed for potential antimalarial drug development. Additionally, the researcher has examined seasonal patterns of malaria, including its prevalence in communities with prolonged transmission periods, emphasizing the importance of early diagnostic testing to prevent severe cases among vulnerable populations.

Key Research Themes (1)
Health Sciences

Malaria Research and Control

Publications (27)

Clinical malaria in three ecological zones in the Volta and Oti Regions of Ghana

Open Access

Plasmodium falciparum Subtilisin-like Domain-Containing Protein (PfSDP), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with Plasmodium falciparum

Open Access
2025Malaria Research and ControlDOI: 10.3390/cells14151184

<em>Plasmodium falciparum</em> Subtilisin-Like Domain Containing Protein ((PfSDP) PF3D7_1105800), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with <em>Plasmodium falciparum</em>

Open Access
2025Malaria Research and ControlDOI: 10.20944/preprints202504.0407.v1

Two quantitative multiplex assays for the detection of P. falciparum asexual rings and male/female gametocyte developmental stages from human tissues

Open Access
2024Malaria Research and ControlDOI: 10.21203/rs.3.rs-4384912/v1

The temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana

Open Access
2023Malaria Research and ControlDOI: 10.1186/s12936-023-04712-1

The global transcriptome of <i>Plasmodium falciparum</i> mid-stage gametocytes (stages II–IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates

Open Access
2023Malaria Research and ControlDOI: 10.1128/spectrum.03820-22

Prevalence of Plasmodium falciparum gametocytaemia in asymptomatic school children before and after treatment with dihydroartemisinin-piperaquine (DP)

Open Access
2023Malaria Research and ControlDOI: 10.1016/j.parepi.2023.e00292

Parasite clearance dynamics in children hospitalised with severe malaria in the Ho Teaching Hospital, Volta Region, Ghana

Open Access
2022Malaria Research and ControlDOI: 10.1016/j.parepi.2022.e00276

Targeting the Plasmodium falciparum proteome and organelles for potential antimalarial drug candidates

Open Access
2022Malaria Research and ControlDOI: 10.1016/j.heliyon.2022.e10390

Generation of Plasmodium falciparum Gametocytes In Vitro with Specific Considerations for Field Isolates

2022Malaria Research and ControlDOI: 10.1007/978-1-0716-2189-9_11

Plasmodium falciparum histidine-rich protein 2 diversity in Ghana

Open Access
2020Malaria Research and ControlDOI: 10.1186/s12936-020-03328-z

Plasmodium falciparum histidine-rich protein 2 (PfHRP2) diversity in Ghana

Open Access
2020Malaria Research and ControlDOI: 10.21203/rs.3.rs-15776/v1

Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites

Open Access
2019Malaria Research and ControlDOI: 10.3389/fimmu.2019.00136

Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria

Open Access
2019Malaria Research and ControlDOI: 10.3389/fimmu.2018.03126

Molecular and immunological characterization of selected Plasmodium falciparum gametocyte-specific genes

Open Access
2019Malaria Research and ControlDOI: 10.21955/aasopenres.1115098.1

Plasmodium falciparum malaria cases detected for prompt treatment by rapid diagnostic tests in the Ho Teaching Hospital of the Volta Region of Ghana

Open Access
2018Malaria Research and ControlDOI: 10.1016/j.parepi.2018.e00072

Gametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria

Open Access
2018Malaria Research and ControlDOI: 10.4269/ajtmh.18-0077

ANTIBODY RESPONSES TO SURFACE ANTIGENS OF <i>PLASMODIUM FALCIPARUM</i> GAMETOCYTE-INFECTED ERYTHROCYTES AND THEIR RELATION TO GAMETOCYTAEMIA

Open Access
2017Malaria Research and ControlDOI: 10.1136/bmjgh-2016-000260.83

Seasonal Prevalence of Malaria, Fever, Anaemia and Factors Associated with Malaria Prevalence among Children Less than Five in an Area with Prolonged Malaria Transmission in Ghana

Open Access
2017Malaria Research and ControlDOI: 10.9734/ijtdh/2017/31371

Comparison of malaria diagnostic methods in four hospitals in the Volta region of Ghana

Open Access
2016Malaria Research and ControlDOI: 10.5281/zenodo.10797112

Antibody responses to surface antigens of <i>Plasmodium falciparum</i> gametocyte‐infected erythrocytes and their relation to gametocytaemia

Open Access
2016Malaria Research and ControlDOI: 10.1111/pim.12323

Immune evasion by &amp;lt;i&amp;gt;Plasmodium falciparum&amp;lt;/i&amp;gt; parasites: converting a host protection mechanism for the parasite′s benefit

Open Access
2016Malaria Research and ControlDOI: 10.4236/aid.2016.62011

Inactivation of Plasmodium falciparum in whole body by riboflavin plus irradiation

Open Access
2014Malaria Research and Control

Inactivation of <i><scp>P</scp>lasmodium falciparum</i> in whole blood by riboflavin plus irradiation

2013Malaria Research and ControlDOI: 10.1111/trf.12235

Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children

Open Access
2013Malaria Research and ControlDOI: 10.1016/j.ijpddr.2013.01.001

Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes

Open Access
2012Malaria Research and ControlDOI: 10.1186/1475-2875-11-429

Recognition of Plasmodium falciparum gametocyte surface antigens by plasma antibodies in asymptomatic Ghanaian school children

Open Access
2012Malaria Research and ControlDOI: 10.1186/1475-2875-11-s1-p24
Academic Metrics
DepartmentDepartment of Clinical Microbiology
Total Publications27
Research Themes1
Open Access Papers25

Department of Clinical Microbiology

Kwame Nkrumah University of Science and Technology

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