Bismarck Dinko
The researcher has conducted extensive research on malaria detection, diagnosis, treatment, and control in Ghana. Their work focuses on identifying Plasmodium species after asymptomatic infections using various methods, characterizing their gene expression patterns within host cells, and developing diagnostic tools to prevent malaria in children less than five years old. The findings highlight the effectiveness of treatments like ACT (Asymptomatic Gibbs Reproductive Infection) in detecting specific malaria parasites and suggest that immune evasion mechanisms, such as cross-stage antigenic targeting, can be harnessed for potential antimalarial drug development. Additionally, the researcher has examined seasonal patterns of malaria, including its prevalence in communities with prolonged transmission periods, emphasizing the importance of early diagnostic testing to prevent severe cases among vulnerable populations.
Malaria Research and Control
Clinical malaria in three ecological zones in the Volta and Oti Regions of Ghana
Open AccessPlasmodium falciparum Subtilisin-like Domain-Containing Protein (PfSDP), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with Plasmodium falciparum
Open Access<em>Plasmodium falciparum</em> Subtilisin-Like Domain Containing Protein ((PfSDP) PF3D7_1105800), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with <em>Plasmodium falciparum</em>
Open AccessTwo quantitative multiplex assays for the detection of P. falciparum asexual rings and male/female gametocyte developmental stages from human tissues
Open AccessThe temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana
Open AccessThe global transcriptome of <i>Plasmodium falciparum</i> mid-stage gametocytes (stages II–IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates
Open AccessPrevalence of Plasmodium falciparum gametocytaemia in asymptomatic school children before and after treatment with dihydroartemisinin-piperaquine (DP)
Open AccessParasite clearance dynamics in children hospitalised with severe malaria in the Ho Teaching Hospital, Volta Region, Ghana
Open AccessTargeting the Plasmodium falciparum proteome and organelles for potential antimalarial drug candidates
Open AccessGeneration of Plasmodium falciparum Gametocytes In Vitro with Specific Considerations for Field Isolates
Plasmodium falciparum histidine-rich protein 2 diversity in Ghana
Open AccessPlasmodium falciparum histidine-rich protein 2 (PfHRP2) diversity in Ghana
Open AccessImmune Responses to the Sexual Stages of Plasmodium falciparum Parasites
Open AccessLow Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
Open AccessMolecular and immunological characterization of selected Plasmodium falciparum gametocyte-specific genes
Open AccessPlasmodium falciparum malaria cases detected for prompt treatment by rapid diagnostic tests in the Ho Teaching Hospital of the Volta Region of Ghana
Open AccessGametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria
Open AccessANTIBODY RESPONSES TO SURFACE ANTIGENS OF <i>PLASMODIUM FALCIPARUM</i> GAMETOCYTE-INFECTED ERYTHROCYTES AND THEIR RELATION TO GAMETOCYTAEMIA
Open AccessSeasonal Prevalence of Malaria, Fever, Anaemia and Factors Associated with Malaria Prevalence among Children Less than Five in an Area with Prolonged Malaria Transmission in Ghana
Open AccessComparison of malaria diagnostic methods in four hospitals in the Volta region of Ghana
Open AccessAntibody responses to surface antigens of <i>Plasmodium falciparum</i> gametocyte‐infected erythrocytes and their relation to gametocytaemia
Open AccessImmune evasion by &lt;i&gt;Plasmodium falciparum&lt;/i&gt; parasites: converting a host protection mechanism for the parasite′s benefit
Open AccessInactivation of Plasmodium falciparum in whole body by riboflavin plus irradiation
Open AccessInactivation of <i><scp>P</scp>lasmodium falciparum</i> in whole blood by riboflavin plus irradiation
Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children
Open AccessExpression of a type B RIFIN in Plasmodium falciparum merozoites and gametes
Open AccessRecognition of Plasmodium falciparum gametocyte surface antigens by plasma antibodies in asymptomatic Ghanaian school children
Open AccessDepartment of Clinical Microbiology
Kwame Nkrumah University of Science and Technology