Gustav Komlaga
The overall research focus is centered around innovative plant-based treatments for health conditions, employing diverse methodologies such as traditional pharmacology, bioactivity studies, and synthetic approaches to address various therapeutic needs across different organisms.
Faculty Biography
I am an Associate Professor of Pharmacognosy at KNUST, with a dual academic background, holding a PhD in Pharmacognosy (KNUST, Kumasi, Ghana) and Microbiology (University of Paris-Saclay, Chatenay Malabry, France). My interdisciplinary training empowers me to approach the field of natural products research with a comprehensive understanding of both the botanical and microbiological sciences.As a dedicated Natural Products Scientist, my research focuses on exploring medicinal plants for their potential therapeutic applications, with a special emphasis on infectious diseases such as malaria. I am committed to validating the efficacy and safety of herbal medicines traditionally used in Ghanaian communities, aiming to bridge the gap between traditional knowledge and modern scientific inquiry. Through my work, I seek to provide robust scientific evidence to support the rational and effective use of medicinal plants, thereby facilitating their acceptance in both local and global healthcare settings.My research also extends to the discovery of novel bioactive compounds from medicinal plants, with the goal of identifying drug candidates for the treatment of various diseases. Additionally, I am passionate about documenting and preserving the rapidly diminishing traditional knowledge of medicinal plant use, particularly among the communities in Northern Ghana and the Volta Region, where the health benefits of leafy vegetables are often overlooked.Currently, I am leading translational research efforts aimed at developing herbal products that are not only effective but also safe, ensuring they meet global healthcare standards. I strive to contribute to the creation of sustainable and accessible health solutions, particularly in resource-limited settings.With over 20 peer-reviewed publications in prestigious scientific journals, I have also contributed to numerous local and international conferences, furthering discourse on the potential of natural products in modern medicine. My expertise has led me to serve as an editorial board member and peer reviewer for several esteemed journals, including Journal of Ethnopharmacology, Phytochemistry Letters, Parasitology Research, Evidence-based Complementary and Alternative Medicine, Advances in Medicinal Plant Research, African Journal of Biotechnology, Journal of Drug Development and Clinical Trials, and International Journal of Pharmaceutical Science and Developmental Research.In addition to my academic and research commitments, I am an active member of professional organizations such as the University Teachers Association of Ghana (UTAG), the Pharmaceutical Society of Ghana (PSGH), and the West African Network of Natural Products Research Scientists (WANNPRES).I completed my O'Level education at Asuom Secondary School in the Eastern Region of Ghana and my A'Level studies at Mawuli School in Ho, Volta Region.
Agriculture and Rural Development Research
Biological Stains and Phytochemicals
Carbohydrate Chemistry and Synthesis
Diverse Scientific Research Studies
Drug-Induced Hepatotoxicity and Protection
Enzyme Production and Characterization
Essential Oils and Antimicrobial Activity
Ethnobotanical and Medicinal Plants Studies
Heavy Metals in Plants
Insect Pest Control Strategies
Malaria Research and Control
Morinda citrifolia extract uses
Moringa oleifera research and applications
Mycorrhizal Fungi and Plant Interactions
Natural Antidiabetic Agents Studies
Natural product bioactivities and synthesis
PARP inhibition in cancer therapy
Phytochemistry and Bioactivity Studies
Phytochemistry and Biological Activities
Saffron Plant Research Studies
Seed and Plant Biochemistry
Synthesis and bioactivity of alkaloids
Traditional and Medicinal Uses of Annonaceae
<i>Duranta erecta</i> L. extracts exert hepatoprotective effect on CCl4-induced toxicity via inactivating NF-kB pathway
Open AccessAntidiabetic Activity of a Ghanaian Herbal Product, DBT-57A: An Observational Study
Open AccessAntimalarial activity of the aqueous extract and anthraquinones from the root of Senna siamea (LAM) H.S. Irwin & Barneby (Fabaceae).
Open AccessA bioactive fraction from the leaves of Ceiba pentandra (L.) Gaertn. exhibits antiproliferative activity via cell cycle arrest at the G1/S checkpoint and initiation of apoptosis via poly [ADP-ribose] polymerase 1 (PARP1) cleavage in HeLa cells.
Malaria: Epidemiology, Life Cycle of Parasite, Control Strategies and Potential Drug Screening Techniques
Open AccessIn vitro cytotoxic activity of five Ghanaian plants on human cancer cell lines
Open AccessIn vitro antiproliferative activities of some Ghanaian medicinal plants
Open AccessIn Vitro Cytotoxic Activity of Five Ghanaian Plants on Human Cancer Cell Lines
Open AccessA review of preclinical evidence of Cryptolepis nigrescens (Wennberg) L. Joubert. and Bruyns., Prosopsis africana (Guill. and Perr.) Taub. and Pterygota macrocarpa K. Schum. traditionally used to manage tumours in Ghana
Ethnobotanical study of medicinal plants used to treat HIV, cancer and diabetes in some communities of Ashanti Region, Ghana
Antimalarial Properties of <i>Sida cordifolia</i> L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression
Open AccessSafety evaluation of hydroethanolic fruit extracts of Duranta erecta Linn
Open AccessSafety evaluation of hydroethanolic fruit extracts of Duranta erecta Linn
Open AccessHura crepitans stem bark extract: A potential remedy to sub-acute liver damage
Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.
Open AccessEvaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts
Open AccessExtracts of Hura crepitans L. stem bark attenuate liver injury and inflammation induced by CCl4 in rats
Five new cassane diterpenes from the seeds and bark of Erythrophleum suaveolens
Open AccessPhytochemical, Antioxidant and Safety Evaluation of Hura crepitans (L.) Stem Bark Hydroethanolic Extract in Animals
Open AccessToxicity of the Hydroethanolic Leaves Extract of Duranta erecta L. in Rat Models
Toxicity of the Hydroethanolic Leaves Extract of Duranta erecta L. in Rat Models
Open AccessHepatoprotective Potential of Hura crepitans L.: A Review of Ethnomedical, Phytochemical and Pharmacological Studies
Open AccessEvaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market
Open AccessPhytochemical, Antimicrobial, and Antioxidant Profiles of <i>Duranta erecta</i> L. Parts
Open AccessPhytochemistry, proximate and antioxidant properties of some indigenous leafy vegetables
Open AccessToxicity and Safety Implications of Herbal Medicines Used in Africa
Open AccessAntiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine
Antileishmanial and Trypanocidal Activities of Extracts and Aporphine Alkaloids Isolated from Monodora Genus (Annonaceae)
Open AccessPyrrolidine alkaloids and their glycosylated derivatives from the root bark of Dichrostachys cinerea (L) Wight & Arn. (Fabaceae)
Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana
The Antimalarial Potential of Three Ghanaian Medicinal Plants
Open AccessSearch for antiplasmodial compounds from Ghanaian medicinal plants
Open AccessMedicinal plants and finished marketed herbal products used in the treatment of malaria in the Ashanti region, Ghana
Cassane diterpenoids from stem bark of Erythrophleum suaveolens [(Guill. et Perr.), Brenan]
The Antimalarial Potential of Three Ghanaian Medicinal Plants
Open AccessVegetative growth of different strains of Pleurotus and Lentinula species on cassava (Manihot esculenta) and yam (Dioscorea rotundata) wastes in Ghana.
Anti-Inflammatory, Antioxidant, and Selective Antibacterial Effects of <i>Euadenia eminens</i> Root Bark
Open AccessHypoglycaemic and Antioxidant Activities of the Stem Bark of Morinda Lucida Benth in Streptozotocin – Induced Diabetic Rats
Pharmacognostic Standardization of the Leaves and Root Bark of Caesalpinia benthamiana
Acaricidal effect of an isolate from Hoslundia opposita vahl against Amblyomma variegatum (Acari: Ixodidae)
Open AccessAntibacterial, anti-inflammatory, and antioxidant effects of the leaves and stem bark of Glyphaea brevis (Spreng) Monachino (Tiliaceae): A comparative study
Open AccessAntiypertensive action of ethanolic extract of Imperata cylindrica leaves in animal models.
Open AccessInfluence of variety and growth environment on β-amylase activity of flour from sweet potato (Ipomea batatas)
Antimicrobial Activity Of Essential Oils Of <i>Xylopia aethiopica</i>
Open AccessFlavonoid constituents of the mature fruit of Tetrapleura tetraptera schum. Et Thonn.)
Open AccessANTIMICROBIAL ACTIVITY OF Hymenostegia afzelii AND Napoleanea vogelii
Open AccessProceedings of quarter 2 and year 2 project review meeting. Final report 2 on project outputs 5.1, 5.2 and 5.3. Food Research Institute (FRI), Accra, Ghana. 19 pp.
Department of Pharmacognosy
Kwame Nkrumah University of Science and Technology