Philomena Entsie
Department of Herbal MedicineLife SciencesHealth SciencesPhysical Sciences

Philomena Entsie

25 Publications19 Research Themes20 Open Access
Research Overview & Focus

This researcher has significantly contributed to medical and biological research across diverse areas, including immune signaling pathways such as P2Y12 receptors, their role in immune response studies, effects of purinergic blockers on sepsis, environmental health risks from heavy metals, medication adherence in chronic diseases, polyphenolic properties in plant cell walls, traditional herbal medicine applications, and innovative approaches to kidney disease management.

Faculty Biography

Miss Philomena Entsie is a Faculty member at the Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, KNUST. She loves to inspire and impact her knowledge and experiences gained to others. Miss Entsie is committed to mentoring the younger generation.

Key Research Themes (19)
Life Sciences

Adenosine and Purinergic Signaling

Life Sciences

Advances in Cucurbitaceae Research

Health Sciences

Antiplatelet Therapy and Cardiovascular Diseases

Life Sciences

Cassava research and cyanide

Health Sciences

Complementary and Alternative Medicine Studies

Health Sciences

COVID-19 Impact on Reproduction

Health Sciences

Dialysis and Renal Disease Management

Life Sciences

Ethnobotanical and Medicinal Plants Studies

Health Sciences

Heart Failure Treatment and Management

Physical Sciences

Heavy metals in environment

Life Sciences

Immune cells in cancer

Health Sciences

Inflammatory Biomarkers in Disease Prognosis

Health Sciences

Liver Disease and Transplantation

Health Sciences

Medication Adherence and Compliance

Life Sciences

Polysaccharides and Plant Cell Walls

Life Sciences

Polysaccharides Composition and Applications

Life Sciences

Proteins in Food Systems

Life Sciences

Traditional and Medicinal Uses of Annonaceae

Health Sciences

Wound Healing and Treatments

Publications (25)

Co-treatment of ticagrelor and anti-PD-1 immunotherapy in tumor-associated macrophages reduces pancreatic cancer cell growth and migration through the TGF-β1/Smad2 pathway

Open Access

P2Y<sub>12</sub>activation in the spleen during sepsis

2025Liver Disease and TransplantationDOI: 10.1152/physiol.2025.40.s1.1181

Blockade of purinergic receptors P2Y<sub>1</sub>or P2Y<sub>12</sub>prevents intestinal barrier damage and platelet sequestration in intra-abdominal sepsis in female mice

2025Adenosine and Purinergic SignalingDOI: 10.1152/physiol.2025.40.s1.0981

Sex-specific activation of platelet purinergic signaling is key in local cytokine release and phagocytosis in the peritoneal cavity in intra-abdominal sepsis

Open Access
2025Dialysis and Renal Disease ManagementDOI: 10.1152/ajpcell.00116.2024

Targeting purinergic signaling in platelets ameliorates the bacterial burden and reduces the cytokine storm in the peritoneal cavity during intra-abdominal sepsis

2024COVID-19 Impact on ReproductionDOI: 10.1152/physiol.2024.39.s1.2065

A role for platelets in metabolic reprogramming of tumor-associated macrophages

Open Access
2023Immune cells in cancerDOI: 10.3389/fphys.2023.1250982

Evaluation of the microbial quality of commercial liquid herbal preparations on the Ghanaian market

Open Access
2023Complementary and Alternative Medicine StudiesDOI: 10.36922/itps.0425

Platelet P2Y<sub>12</sub> signalling pathway in the dysregulated immune response during sepsis

Open Access
2023Antiplatelet Therapy and Cardiovascular DiseasesDOI: 10.1111/bph.16207

Blocking purinergic signaling alters platelet and macrophage crosstalk and phagocytic ability in the peritoneal cavity during intra-abdominal sepsis

2023Inflammatory Biomarkers in Disease PrognosisDOI: 10.1152/physiol.2023.38.s1.5785322

The Signaling Pathway of the ADP Receptor P2Y12 in the Immune System: Recent Discoveries and New Challenges

Open Access
2023Adenosine and Purinergic SignalingDOI: 10.3390/ijms24076709

Sex-related differences in the response of anti-platelet drug therapies targeting purinergic signaling pathways in sepsis

Open Access
2022Heart Failure Treatment and ManagementDOI: 10.3389/fimmu.2022.1015577

Investigation of the physicochemical properties of freeze-dried fruit pulp of Telfairia occidentalis and its potential use as suspending agent

Open Access
2022Advances in Cucurbitaceae ResearchDOI: 10.1016/j.heliyon.2022.e09997

Pharmaceutical Assessment of Melia azedarach Gum as a Binder and Disintegrant in Immediate-Release Tablets

Open Access
2022Proteins in Food SystemsDOI: 10.1155/2022/9810099

Pharmaceutical Applications of Glucose Syrup from High Quality Cassava Flour in Oral Liquid Formulations

Open Access
2022Cassava research and cyanideDOI: 10.1155/2022/6869122

Formulation and Pharmaceutical Assessment of Annona muricata Oral Capsules and Suspension as Antidiarrhea Dosage Forms

Open Access
2021Traditional and Medicinal Uses of AnnonaceaeDOI: 10.1155/2021/1792437

Evaluation of the binding and disintegrating properties of gum obtained from the stem bark of Cinnamomum zeylanicum

Open Access
2021Polysaccharides Composition and ApplicationsDOI: 10.17159/sajs.2021/11550

Antimicrobial, antioxidant and wound healing activities of methanol leaf extract of Bridelia micrantha (Hochst.) Baill.

Open Access
2021Wound Healing and TreatmentsDOI: 10.1016/j.sciaf.2021.e00980

Health risk assessment of trace metals in selected food crops at Abuakwa South Municipal, Ghana

2021Heavy metals in environmentDOI: 10.1007/s10661-021-09373-8

Wound Management Property of a Hydroethanolic Leaf Extract of Cnestis ferruginea DC

Open Access
2021Wound Healing and TreatmentsDOI: 10.1155/2021/6693718

Formulation and In Vitro Evaluation of Oral Capsules from Liquid Herbal Antimalarials Marketed in Ghana

Open Access
2021Ethnobotanical and Medicinal Plants StudiesDOI: 10.1155/2021/6694664

Pectin from Okra (Abelmoschus esculentus L.) Has Potential as a Drug Release Modifier in Matrix Tablets

Open Access
2021Polysaccharides Composition and ApplicationsDOI: 10.1155/2021/6672277

Utilization of Pectin from Okra as Binding Agent in Immediate Release Tablets

Open Access
2021Polysaccharides and Plant Cell WallsDOI: 10.1155/2021/6002286

The Role of the Patient Information Leaflet in Patients’Medication Therapy: A Case Study within the Kumasi Metropolis of Ghana

Open Access
2020Medication Adherence and ComplianceDOI: 10.1155/2020/2489137

Patients’ belief and adherence to their medication therapy in the Bawku municipality

Open Access
2020Medication Adherence and ComplianceDOI: 10.22271/tpi.2020.v9.i8a.5033
Academic Metrics
DepartmentDepartment of Herbal Medicine
Total Publications25
Research Themes19
Open Access Papers20

Department of Herbal Medicine

Kwame Nkrumah University of Science and Technology

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