Kwadwo Owusu Akuffo
Department of Optometry and Visual ScienceHealth SciencesLife SciencesSocial SciencesPhysical Sciences

Kwadwo Owusu Akuffo

80 Publications32 Research Themes69 Open Access
Research Overview & Focus

The researcher has published several papers focusing on retinal disease management in Ghana, covering themes such as macular pigments, supplementations for macular degeneration, treatments for other retinal disorders, and interventions against blindness. Despite some notable advancements, there is a need for further systematic reviews to integrate findings from these diverse studies. The research highlights strategies like supplementing with carotenoids, employing light exposure, and addressing visual impairments in a unified approach. Future work should explore the relationship between light factors and macular pigments to better understand their effects on vision care in Ghana.

Faculty Biography

Dr Kwadwo Owusu Akuffo is a Senior Lecturer and Former Head of Department, Optometry and Visual Science, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana, where he contributes to training the next generation of optometrists and vision scientists. He completed his Doctor of Philosophy (PhD) degree in 2017 at the Nutrition Research Centre Ireland, Waterford Institute of Technology, Waterford, Ireland; investigating the impact of macular carotenoid and co-antioxidant supplementation on visual function in patients with early age-related macular degeneration. His PhD work was supported by the European Research Council Grant 281096.Dr Akuffo studied Doctor of Optometry (OD) at KNUST, graduating in 2011. During his studies at KNUST, he was on the Faculty of Biosciences Dean’s Honours List on three consecutive occasions for outstanding academic performance.Dr Akuffo has been trained in retinal photograph grading at the Moorfields Eye Hospital Reading Centre, London, UK, and has been certified to grade cataracts using the Lens Opacities Classification System (LOCS) III by the Chylack Incorporated.Dr Akuffo has published over 40 scientific peer-reviewed articles and has contributed to several conference proceedings in his research field. He currently has external collaborations with the Human Sciences Research Council (HSRC; South Africa) where he is using data from the South African National Health and Nutrition Examination Survey (SANHANES) to investigate prevalence of Eye Disease and its associated risk factors in South Africa. He is a Fellow of the American Academy of Optometry (AAO) and a member of the Ghana Optometric Association (GOA). He was recognized for his scientific excellence as ‘Affiliate of the African Academy of Sciences’ following a competitive evaluation process.He is a Reviewer for the several journals including Investigative Ophthalmology and Visual Science, British Journal of Ophthalmology, Ophthalmic Research, International Journal of Vitreous and Retina, and Eye and Vision. Currently, he serves as an Associate Editor for BMC Ophthalmology.In addition to his academic and research work, Dr. Akuffo is very passionate about mentorship and the career development of young people. Throughout his mentorship, students have won several prestigious international awards including the Harvard Crossroads Emerging Leaders Program (CELP) Fellowship, and Developing Country Eye Researcher Travel Fellowship (DCERF). Dr. Akuffo currently serves as a Board Member of the African STEM Network and Youth Arise Organization.

Key Research Themes (32)
Health Sciences

Antioxidant Activity and Oxidative Stress

Health Sciences

Biochemical effects in animals

Health Sciences

Cardiovascular Syncope and Autonomic Disorders

Health Sciences

Child Nutrition and Water Access

Life Sciences

Circadian rhythm and melatonin

Life Sciences

Date Palm Research Studies

Health Sciences

Diabetes Management and Research

Social Sciences

Diversity and Career in Medicine

Health Sciences

Glaucoma and retinal disorders

Health Sciences

Global Maternal and Child Health

Health Sciences

HIV/AIDS Research and Interventions

Physical Sciences

Impact of Light on Environment and Health

Health Sciences

Infant Development and Preterm Care

Health Sciences

Malaria Research and Control

Health Sciences

Maternal Mental Health During Pregnancy and Postpartum

Social Sciences

Multisensory perception and integration

Health Sciences

Obesity, Physical Activity, Diet

Health Sciences

Ocular Infections and Treatments

Health Sciences

Ophthalmology and Visual Health Research

Health Sciences

Ophthalmology and Visual Impairment Studies

Life Sciences

Parasites and Host Interactions

Health Sciences

Patient Satisfaction in Healthcare

Social Sciences

Pharmaceutical Economics and Policy

Life Sciences

Pharmacovigilance and Adverse Drug Reactions

Health Sciences

Retinal and Macular Surgery

Health Sciences

Retinal Diseases and Treatments

Health Sciences

Retinal Imaging and Analysis

Life Sciences

Salmonella and Campylobacter epidemiology

Health Sciences

SARS-CoV-2 and COVID-19 Research

Life Sciences

Stress Responses and Cortisol

Health Sciences

Travel-related health issues

Health Sciences

Ureteral procedures and complications

Publications (80)

Optimizing glaucoma care in Ghana: a mixed-methods study of optometrists' practices, challenges, and capacity needs

Open Access

Enhanced School-Based Vision Screening in Kumasi, Ghana: A Pilot Study to Assess Feasibility

Open Access

An integrative examination of psychological distress and its nutritional and visual correlates among young adults in Ghana

Open Access

Poverty, food insecurity and dietary patterns as drivers of infant growth outcomes in rural Ghana: implications for community nutrition programs

Surgery-related obstetric fistulas across health facilities in sub-Saharan African countries: systematic review and meta-analysis

Open Access
2025Ureteral procedures and complicationsDOI: 10.1101/2025.09.25.25336674

Physiologically relevant real-world light exposure and its behavioural and environmental determinants in Kumasi, Ghana

Open Access
2025Circadian rhythm and melatoninDOI: 10.12688/openreseurope.21304.1

Artificial intelligence applications in refractive error management: A systematic review and meta-analysis

Open Access
2025Retinal Imaging and AnalysisDOI: 10.1371/journal.pdig.0000904

Physiologically relevant real-world light exposure and its behavioural and environmental determinants in Kumasi, Ghana

Open Access
2025Impact of Light on Environment and HealthDOI: 10.1101/2025.09.11.25334564

An integrative examination of psychological distress and its nutritional and visual correlates among young adults in Ghana

Open Access
2025Stress Responses and CortisolDOI: 10.1101/2025.08.01.25332578

Accessibility and challenges to ophthalmic instruments acquisition among optometry students in Ghana

Open Access
2025Ophthalmology and Visual Health ResearchDOI: 10.1186/s13104-025-07385-y

Dietary factors and predominant eye diseases in sub-Saharan African populations: A systematic review protocol

Open Access
2025Retinal Imaging and AnalysisDOI: 10.1371/journal.pone.0320030

Breastfeeding and Complementary Feeding are Associated With Cognition and Vision in Rural Ghanaian Infants

Open Access
2025Child Nutrition and Water AccessDOI: 10.1002/rfc2.70025

Accessibility and Challenges to Ophthalmic Instruments Acquisition among Optometry Students in Ghana

Open Access
2025Ophthalmology and Visual Health ResearchDOI: 10.21203/rs.3.rs-6437290/v1

Dietary Factors and Predominant Eye Diseases in Sub-Saharan African Populations: A Comprehensive Systematic Review Protocol

Open Access
2025Travel-related health issuesDOI: 10.1101/2025.02.17.25322272

Protocol for a prospective, multicentre, cross-sectional cohort study to assess personal light exposure

Open Access
2024Circadian rhythm and melatoninDOI: 10.1186/s12889-024-20206-4

Knowledge, Attitude, and Perception of African Optometrists on Fellowship of the American Academy of Optometry (AAO): A Cross-Sectional Survey

Open Access
2024Diversity and Career in MedicineDOI: 10.2147/opto.s478512

Mental health problems in pregnant and postpartum women living with HIV in sub-Saharan Africa: Systematic review and meta-analysis protocol

Open Access
2024Maternal Mental Health During Pregnancy and PostpartumDOI: 10.1371/journal.pone.0308810

The burden of iatrogenic obstetric fistulas in Sub-Saharan Africa: Systematic review and meta-analysis protocol

Open Access
2024Ureteral procedures and complicationsDOI: 10.1371/journal.pone.0302529

Elucidating fungi pathogens and multi-drug resistance in oculomycosis, and bioprospecting native plants as antifungal therapy

Open Access
2024Ocular Infections and TreatmentsDOI: 10.21203/rs.3.rs-4656890/v1

Praziquantel-related visual disorders among recipients in mass drug administration campaigns in schistosomiasis endemic settings: Systematic review and meta-analysis protocol

Open Access
2024Parasites and Host InteractionsDOI: 10.1371/journal.pone.0300384

Elucidating fungal etiology and multi-drug resistance in oculomycosis and bioprospecting native medical plants as candidates for antifungal therapy

Open Access
2024Ocular Infections and TreatmentsDOI: 10.21203/rs.3.rs-4103929/v1

Low Vision Practice and Service Provision Among Optometrists in Ghana: A Nationwide Survey

2024Ophthalmology and Visual Health ResearchDOI: 10.1080/09286586.2024.2317816

Protocol for a prospective, multicentre, cross-sectional cohort study to assess personal light exposure

Open Access
2024Circadian rhythm and melatoninDOI: 10.1101/2024.02.11.24302663

Malaria vaccine-related adverse events among children under 5 in sub-Saharan Africa: systematic review and meta-analysis protocol

Open Access
2023Malaria Research and ControlDOI: 10.1136/bmjopen-2023-076985

Psychosocial interventions and their effectiveness on quality of life among elderly persons living with HIV in Africa South of the Sahara: Systematic review and meta -analysis protocol

Open Access
2023HIV/AIDS Research and InterventionsDOI: 10.1371/journal.pone.0291781

Low vision practice and service provision among Optometrists in Ghana: a nationwide survey

Open Access
2023Ophthalmology and Visual Impairment StudiesDOI: 10.1101/2023.07.16.23292720

Macular Pigment, Cognition, and Visual Function in Younger Healthy Adults in Ghana

2023Retinal Imaging and AnalysisDOI: 10.3233/jad-230233

Malaria and typhoid fever among patients presenting with febrile illnesses in Ga West Municipality, Ghana

Open Access
2023Salmonella and Campylobacter epidemiologyDOI: 10.1371/journal.pone.0267528

Clinical characteristics of external bacterial ocular and periocular infections and their antimicrobial treatment patterns among a Ghanaian ophthalmic population

Open Access
2022Ocular Infections and TreatmentsDOI: 10.1038/s41598-022-14461-x

Malaria and typhoid fever coinfection among patients presenting with febrile illnesses in Ga West Municipality, Ghana

Open Access
2022Salmonella and Campylobacter epidemiologyDOI: 10.1101/2022.04.12.22273780

Safety of praziquantel in persons with and without schistosomiasis: systematic review and meta-analysis

Open Access
2022Parasites and Host InteractionsDOI: 10.1101/2022.03.09.22270839

Prevalence of Childhood Cataract and Associated Factors Among a Pediatric Population at A Tertiary Hospital in Ghana

Open Access
2022Ophthalmology and Visual Health ResearchDOI: 10.21203/rs.3.rs-1321185/v1

Postoperative vision outcomes after cataract surgery in the Eastern region of Ghana

Open Access
2022Ophthalmology and Visual Impairment StudiesDOI: 10.21203/rs.3.rs-1284554/v1

Clinical Characteristics of External Ocular and Periocular Infections and Their Antimicrobial Treatment Patterns Among a Ghanaian Ophthalmic Population; A Multicenter Study

Open Access
2022Ocular Infections and TreatmentsDOI: 10.21203/rs.3.rs-1249919/v1

Spontaneous reporting of adverse drug reaction among health professionals in Ghana

Open Access
2022Pharmacovigilance and Adverse Drug ReactionsDOI: 10.1186/s13690-021-00783-1

Utilization of Facility-based Delivery Services in the Wa Municipality, Ghana

Open Access
2022Global Maternal and Child HealthDOI: 10.21203/rs.3.rs-1250026/v1

Practice patterns in the management of amblyopia among optometrists in Ghana

2022Ophthalmology and Visual Impairment StudiesDOI: 10.1080/09273972.2021.2022715

Determinants of blood glucose control among people with Type 2 diabetes in a regional hospital in Ghana

Open Access
2021Diabetes Management and ResearchDOI: 10.1371/journal.pone.0261455

Spontaneous Reporting of Adverse Drug Reaction Among Health Professionals In Kpone-Katamanso District, Ghana

Open Access
2021Pharmacovigilance and Adverse Drug ReactionsDOI: 10.21203/rs.3.rs-433485/v1

Uptake of HIV Testing and Counselling among the Youth in Kintampo South District, Ghana

Open Access
2021HIV/AIDS Research and InterventionsDOI: 10.21203/rs.3.rs-738547/v2

Regulatory compliance among over-the-counter medicine sellers facilities within the Upper East Region of Ghana

Open Access
2021Pharmaceutical Economics and PolicyDOI: 10.1186/s40545-021-00363-2

Burden of malaria in children under five and caregivers’ health-seeking behaviour for malaria-related symptoms in artisanal mining communities in Ghana

Open Access
2021Malaria Research and ControlDOI: 10.1186/s13071-021-04919-8

Uptake of HIV Testing and Counselling among the Youth in Kintampo South District, Ghana

Open Access
2021HIV/AIDS Research and InterventionsDOI: 10.21203/rs.3.rs-738547/v1

Situational analysis of diabetic retinopathy treatment Services in Ghana

Open Access
2021Retinal Diseases and TreatmentsDOI: 10.1186/s12913-021-06608-9

Seroprevalence of SARS CoV-2 infection in Low and Middle-Income Countries and risk classification in the context of rolling out vaccine candidate across these countries : Protocol for a systematic review and meta-analysis

Open Access
2021SARS-CoV-2 and COVID-19 ResearchDOI: 10.21203/rs.3.rs-578481/v1

Job satisfaction and its associated factors among opticians in Ghana: a cross-sectional study

Open Access
2021Patient Satisfaction in HealthcareDOI: 10.1186/s12960-021-00612-0

Optimal Prevalence Threshold For Guiding The Implementation Of Preventive Chemotherapy In Countries Endemic For Schistosomiasis: Synthesis Of Evidence From Mass Drug Administration Programmes For Developing This Tool

Open Access
2021Parasites and Host InteractionsDOI: 10.1101/2021.05.10.21256643

Vision loss, vision difficulty and psychological distress in South Africa: results from SANHANES-1

Open Access
2021Ophthalmology and Visual Impairment StudiesDOI: 10.1186/s40359-021-00558-x

Job satisfaction and its associated factors among optometrists in Ghana: a cross-sectional study

Open Access
2021Patient Satisfaction in HealthcareDOI: 10.1186/s12955-020-01650-3

Prevalence and associated factors of vision loss in the South African National Health and Nutrition Examination Survey (SANHANES-1)

Open Access
2021Ophthalmology and Visual Impairment StudiesDOI: 10.1186/s12886-020-01714-4

The effect of eye disease, cataract surgery and hearing aid use on multisensory integration in ageing

Open Access
2020Multisensory perception and integrationDOI: 10.1016/j.cortex.2020.08.030

Eye care utilization among diabetics in the South African National Health and Nutrition Examination Survey (SANHANES-1): a cross-sectional study

Open Access
2020Retinal Diseases and TreatmentsDOI: 10.1186/s13104-020-05245-5

Eye care utilization pattern in South Africa: results from SANHANES-1

Open Access
2020Ophthalmology and Visual Impairment StudiesDOI: 10.1186/s12913-020-05621-8

Prevalence and pattern of amblyopia in a rural hospital in Ghana

2020Ophthalmology and Visual Impairment StudiesDOI: 10.1080/09273972.2020.1779319

Career aspirations and factors influencing career choices of optometry students in Ghana

Open Access
2020Diversity and Career in MedicineDOI: 10.1371/journal.pone.0233862

Assessment of availability, awareness and perception of stakeholders regarding preschool vision screening in Kumasi, Ghana: An exploratory study

Open Access
2020Infant Development and Preterm CareDOI: 10.1371/journal.pone.0230117

Orthostatic blood pressure variability is associated with lower visual contrast sensitivity function: Findings from The Irish Longitudinal Study on Aging

2019Glaucoma and retinal disordersDOI: 10.1016/j.exger.2019.01.009

Orthostatic hypertension as a risk factor for age-related macular degeneration: Evidence from the Irish longitudinal study on ageing

2018Retinal Imaging and AnalysisDOI: 10.1016/j.exger.2018.02.029

The Relationship Between Plasma Concentrations of Lutein and Zeaxanthin with Self-Reported and Actual Prevalence of AMD in an Irish Population-Based Sample

Open Access
2017Antioxidant Activity and Oxidative StressDOI: 10.1080/02713683.2017.1403633

The Impact of Supplemental Antioxidants on Visual Function in Nonadvanced Age-Related Macular Degeneration: A Head-to-Head Randomized Clinical Trial

Open Access
2017Retinal Diseases and TreatmentsDOI: 10.1167/iovs.16-21192

Serum and macular response to carotenoid-enriched egg supplementation in human subjects: the Egg Xanthophyll Intervention clinical Trial (EXIT)

Open Access
2017Antioxidant Activity and Oxidative StressDOI: 10.1017/s0007114516003895

Author Response: Comments on Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: CREST - Report 1

Open Access
2016Retinal Diseases and TreatmentsDOI: 10.1167/iovs.16-20498

200 RELATIONSHIP BETWEEN PREVALENCE (AND AWARENESS) OF AGE-RELATED MACULAR DEGENERATION AND PLASMA CONCENTRATIONS OF LUTEIN AND ZEAXANTHIN IN AN OLDER POPULATION

Open Access
2016Biochemical effects in animalsDOI: 10.1093/ageing/afw159.182

Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: Central Retinal Enrichment Supplementation Trials – Report 1

Open Access
2016Antioxidant Activity and Oxidative StressDOI: 10.1167/iovs.16-19520

The Impact of Cataract, and Its Surgical Removal, on Measures of Macular Pigment Using the Heidelberg Spectralis HRA+OCT MultiColor Device

Open Access
2016Glaucoma and retinal disordersDOI: 10.1167/iovs.16-19141

Non-dietary correlates and determinants of plasma lutein and zeaxanthin concentrations in the Irish population

2016Antioxidant Activity and Oxidative StressDOI: 10.1007/s12603-016-0729-7

Relationship between macular pigment and visual function in subjects with early age-related macular degeneration

Open Access
2016Ophthalmology and Visual Impairment StudiesDOI: 10.1136/bjophthalmol-2016-308418

Concordance of Macular Pigment Measurement Using Customized Heterochromatic Flicker Photometry and Fundus Autofluorescence in Age-Related Macular Degeneration

Open Access
2015Retinal Diseases and TreatmentsDOI: 10.1167/iovs.15-17822

Phenotypes of orthostatic blood pressure behaviour and association with visual acuity

2015Cardiovascular Syncope and Autonomic DisordersDOI: 10.1007/s10286-015-0315-9

Cognitive Function and Its Relationship with Macular Pigment Optical Density and Serum Concentrations of its Constituent Carotenoids

Open Access
2015Retinal Diseases and TreatmentsDOI: 10.3233/jad-150199

Sustained supplementation and monitored response with differing carotenoid formulations in early age-related macular degeneration

Open Access
2015Retinal Diseases and TreatmentsDOI: 10.1038/eye.2015.64

Prevalence of age-related macular degeneration in the Republic of Ireland

Open Access
2015Retinal Imaging and AnalysisDOI: 10.1136/bjophthalmol-2014-305768

The Impact of Supplemental Macular Carotenoids in Alzheimer's Disease: A Randomized Clinical Trial

Open Access
2015Antioxidant Activity and Oxidative StressDOI: 10.3233/jad-142265

Prevalence of Overweight and Obesity among Students in the Kumasi Metropolis

Open Access
2015Obesity, Physical Activity, DietDOI: 10.1155/2015/613207

Eye Diseases among Women Engaged in Local Extraction of Palm Kernel Oil in the Kumasi Metropolis

Open Access
2014Date Palm Research StudiesDOI: 10.1155/2014/516183

Macular Pigment, Visual Function, and Macular Disease among Subjects with Alzheimer's Disease: An Exploratory Study

Open Access
2014Antioxidant Activity and Oxidative StressDOI: 10.3233/jad-140507

SUPPLEMENTATION WITH THREE DIFFERENT MACULAR CAROTENOID FORMULATIONS IN PATIENTS WITH EARLY AGE-RELATED MACULAR DEGENERATION

2014Antioxidant Activity and Oxidative StressDOI: 10.1097/iae.0000000000000174

Central Retinal Enrichment Supplementation Trials (CREST): Design and Methodology of the CREST Randomized Controlled Trials

Open Access
2014Retinal Diseases and TreatmentsDOI: 10.3109/09286586.2014.888085

Measuring Visual Function Using the MultiQuity System: Comparison with an Established Device

Open Access
2014Ophthalmology and Visual Impairment StudiesDOI: 10.1155/2014/180317

Central Retinal Enrichment Supplementation Trials (CREST): Design and Methodology

2013Retinal and Macular Surgery
Academic Metrics
DepartmentDepartment of Optometry and Visual Science
Total Publications80
Research Themes32
Open Access Papers69

Department of Optometry and Visual Science

Kwame Nkrumah University of Science and Technology

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