Emmanuel Amankwah Ntim
Department of PhysiologyLife SciencesHealth Sciences

Emmanuel Amankwah Ntim

16 Publications11 Research Themes16 Open Access
Research Overview & Focus

The researcher has conducted extensive work across multiple domains, focusing on the intersection of health sciences and life sciences. Their research is deeply interconnected, with a primary emphasis on prostate cancer treatment and diagnosis, as these areas are closely linked through their focus on biomarkers such as PS A, CRP, and Hgb concentration. Additionally, studies related to heat shock proteins highlight their role in evolutionary biology within prostatic cancer cells, particularly via oxidative stress signaling. The researcher also explores the biological aspects of HIV disease using alcohol consumption data, demonstrating its broader impact on health outcomes. Furthermore, their work on trace elements underscores the importance of understanding nutritional and bioactive compounds for overall health and treatment strategies. This integrative approach across themes reveals a holistic view of prostate cancer research, emphasizing the need for multidisciplinary approaches to enhance treatment and diagnosis.

Faculty Biography

About Dr E. Amankwah NtimDr Ntim is a PhD scientist with a passionate interest in cancer biology, angiogenesis and cancer metastasis.Dr E. Amankwah Ntim is a scientist, employed as a Lecturer and a researcher at the Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. He completed his PhD in Germany in the Institute of Toxicology and Genetics of the Karlsruhe Institute of Technology. He has recently returned from Germany to continue his teaching and research in Ghana. His first current research focuses on the role of The Environment on the development of Benign Prostate Hyperplasia and Prostate cancer. Under this, his team is investigating to understand the role environmental factors such as diet and lifestyle have on the development and progression of BPH and Prostate Cancer. Secondly, he is also screening natural products for novel anti-angiogenic compounds in his quest to target the process of angiogenesis in metastatic cancer.  His current work employs a combination of mouse models, chick chorioallantoic membrane assays, molecular biology, cell biology and histology.Dr E. Amankwah Ntim completed his PhD in 2018 at the Institute for Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany, under the guidance of Prof. Dr. A. C. B. Cato. His doctoral studies dealt with the role of molecular chaperones NPM1 and Bag-1L in the regulation of the Androergen Receptor action in Prostate cancer.  Earlier on, he had undertaken master’s research studies in the department of Physiology, Medical School, KNUST under Dr. K. Bedu-Addo. For his master’s research, he investigated the effect HIV infection and anti-retroviral treatment have on semen quality of HIV-seropositive men in Ghana.In 2001 he completed his General Science Certificate examination at the Ghana Secondary Technical School, Takoradi, after which he moved to Kumasi to start his Bachelor degree programme in the Department of Biological Sciences, KNUST.AWARDS AND HONOURS * Fellowship from the DAAD (Deutscher Akademischer Austauschdienst) for PhD Fellowship for doctoral work at the Karlsruhe Institute of Technology, Germany (2014-18). * Travel fellowship from the Helmholtz Gemeinschaft (2017). * Career and Leadership Development award by Helmholtz Gemeinschaft (2016).

Key Research Themes (11)
Life Sciences

Heat shock proteins research

Health Sciences

HIV-related health complications and treatments

Health Sciences

HIV, Drug Use, Sexual Risk

Health Sciences

Hormonal and reproductive studies

Life Sciences

Moringa oleifera research and applications

Life Sciences

Phytochemical Studies and Bioactivities

Health Sciences

Pregnancy and preeclampsia studies

Health Sciences

Prostate Cancer Diagnosis and Treatment

Health Sciences

Prostate Cancer Treatment and Research

Health Sciences

Tea Polyphenols and Effects

Health Sciences

Trace Elements in Health

Publications (16)

The Burden of Atherosclerotic Cardiovascular Disease Risk Factors Among Adults Living With HIV in the Ashanti Region: A Cross-Sectional Study in Kumasi

Open Access

Antiangiogenic effects of the hydroethanolic root extract of Croton membranaceus in chick chorioallantoic membrane

Open Access
2025Moringa oleifera research and applicationsDOI: 10.21203/rs.3.rs-7782041/v1

The impact of zinc and testosterone co-treatment on tumourigenesis in prostate cancer: a novel model

Open Access
2025Trace Elements in HealthDOI: 10.1186/s12885-025-14893-4

Effect of Dietary Patterns on Testosterone-Induced Prostatic Hyperplasia in Rats

Open Access
2025Hormonal and reproductive studiesDOI: 10.21203/rs.3.rs-6946787/v1

Associations between green tea drinking and body mass index, serum lipid profile and prostate-specific antigen in a Ghanaian population: a cross-sectional study

Open Access
2025Tea Polyphenols and EffectsDOI: 10.1186/s40795-025-01039-9

Association Between Green Tea Drinking with Body Mass Index, Serum Lipid Profile and Prostate Specific-Antigen in a Ghanaian Population: A Cross- Sectional Study

Open Access
2024Tea Polyphenols and EffectsDOI: 10.21203/rs.3.rs-4457445/v1

Ratios of Prostate-Specific Antigen to Albumin, C-reactive Protein, and Haemoglobin Concentration are Valuable Markers to Predict Patients with Either Prostate Cancer or Benign Prostate Hyperplasia

Open Access
2024Prostate Cancer Diagnosis and TreatmentDOI: 10.21203/rs.3.rs-4326102/v1

Association Between Alcohol Consumption and Blood Pressure Levels Among HIV Sero-Positive and Sero-Negative Cohorts: A Secondary Analysis of the Vukuzazzi Study

Open Access
2024HIV-related health complications and treatmentsDOI: 10.1177/21501319241235594

Alcohol consumption and HIV disease prognosis among virally unsuppressed in Rural KwaZulu Natal, South Africa

Open Access
2023HIV, Drug Use, Sexual RiskDOI: 10.3934/medsci.2023018

The antiproliferative, antimigratory and anticlonogenic effects of croton membranaceus m?ll. arg. (euphorbiaceae) hydroethanolic root extract in human 22rv1 castration-resistant prostate cancer cells

Open Access
2023Phytochemical Studies and BioactivitiesDOI: 10.23893/1307-2080.aps6109

A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway

Open Access
2022Heat shock proteins researchDOI: 10.1016/j.isci.2022.104175

Prevalence, placenta development, and perinatal outcomes of women with hypertensive disorders of pregnancy at Komfo Anokye Teaching Hospital

Open Access
2020Pregnancy and preeclampsia studiesDOI: 10.1371/journal.pone.0233817

Prevalence, Placenta Development, and Perinatal Outcomes of Women with Hypertensive Disorders of Pregnancy at Komfo Anokye Teaching Hospital

Open Access
2020Pregnancy and preeclampsia studiesDOI: 10.1101/2020.05.14.095760

The nuclear chaperones NPM1 and Bag-1L in the regulation of androgen receptor action in prostate cancer cells

Open Access
2018Heat shock proteins researchDOI: 10.5445/ir/1000084843

Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

Open Access
2017Prostate Cancer Treatment and ResearchDOI: 10.7554/elife.27159

Author response: Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

Open Access
2017Prostate Cancer Treatment and ResearchDOI: 10.7554/elife.27159.041
Academic Metrics
DepartmentDepartment of Physiology
Total Publications16
Research Themes11
Open Access Papers16

Department of Physiology

Kwame Nkrumah University of Science and Technology

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