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Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition

Paper Details
Authors:
Florencia P. Madorsky Rowdo
Rachel Martini
Sarah E. Ackermann
Colin P. Tang
Marvel Tranquille
Adriana Irizarry
Ilkay Us
Omar Alawa
Jenna E. Moyer
Michael Sigouros
John Nguyen
Majd Al Assaad
Esther Cheng
Paula S. Ginter
Jyothi Manohar
Brian Stonaker
Richard Boateng
Joseph K. Oppong
Ernest Adjei
Baffour Awuah
Ishmael Kyei
Francis Aitpillah
Michael O. Adinku
Kwasi Ankomah
Ernest Osei‐Bonsu
Kofi K. Gyan
Syed A. Hoda
Lisa A. Newman
Juan Miguel Mosquera
Andrea Sboner
Olivier Elemento
Lukas E. Dow
Melissa B. Davis
M. Laura Martín
Publication Date: 2025-02-01
CRISPR and Genetic EngineeringBiochemistry, Genetics and Molecular BiologyMolecular BiologyLife Sciences
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