Sampson Antwi

Child Health

About

Prof Sampson Antwi is a Professor of Child Health and Paediatric Nephrology in the School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi-Ghana.I am also a Paediatric HIV and Malnutrition Expert. I founded the paediatric renal clinic, the paediatric HIV clinic and the malnutrition unit all in Komfo Anokye Teaching Hospital, Kumasi-Ghana. The paediatric HIV clinic is the second largest paediatric HIV clinic in Ghana with over 500 patients.

Research Summary

(inferred from publications by AI)

The research literature underscores a comprehensive approach to understanding neglected tropical diseases, particularly focusing on chronic kidney disease (CKD) in Ghana, where several themes such as neglected malaria research, immunology, HIV/AIDS prevention, andPediatric nephrology are addressed. Methodologies ranging from systematic reviews to clinical trials, pharmacokinetic studies, behavioral assessments, and economic evaluations are employed to explore the etiology, management, and prevention of CKD. These studies highlight the complex interplay between genetics, nutritional status, immunological markers, and social determinants in disease manifestation, emphasizing the need for integrated, multidisciplinary approaches for effective intervention.

Research Themes

All Papers

Genome-wide association study indicates two novel resistance loci for severe malaria(2012)

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study(2018)

Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children(2009)

T Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children(2011)

Capillary refill time as an independent prognostic indicator in severe and complicated malaria(2006)

Assessment of GFR by four methods in adults in Ashanti, Ghana: the need for an eGFR equation for lean African populations(2010)

Urine-Based Detection of Biomarkers Indicative of Chronic Kidney Disease in a Patient Cohort from Ghana(2022)

Urine-based detection of biomarkers indicative of chronic kidney disease in a patient cohort from Ghana(2022)

ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics)(2021)

Peritoneal Dialysis to Treat Patients with Acute Kidney Injury—The Saving Young Lives Experience in West Africa: Proceedings of the Saving Young Lives Session at the First International Conference of Dialysis in West Africa, Dakar, Senegal, December 2015(2017)

Peritoneal Dialysis as a Mode of Treatment for Acute Kidney Injury in Sub-Saharan Africa(2013)

Topic: Acute Kidney Injury in Children: 3-Year Data Review from Ghana(2015)

Acute Kidney Injury in Children: A 3-Year Retrospective Analysis at Komfo Anokye Teaching Hospital, Ghana(2021)

ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics)(2021)

APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans(2024)

Management of idiopathic childhood nephrotic syndrome in sub-Saharan Africa: Ibadan consensus statement(2020)

HIV Viremia Is Associated With APOL1 Variants and Reduced JC-Viruria(2021)

Quality of life among Ghanaian adolescents living with perinatally acquired HIV: a mixed methods study(2015)

HIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status(2015)

High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana(2018)

SANKOFA(2015)

HIV infection in severely malnourished children in Kumasi, Ghana: a cross-sectional prospective study(2013)

Clinic-Based Pediatric Disclosure Intervention Trial Improves Pediatric HIV Status Disclosure in Ghana(2020)

Prevalence and correlates of depression among caregivers of children living with HIV in Ghana: findings from the Sankofa pediatric disclosure study(2018)

Illness Narratives of Children Living with HIV Who Do Not Know Their HIV Status in Ghana: I’m Sick, But I Don’t Know the Sickness—A Qualitative Study(2020)

Sankofa pediatric HIV disclosure intervention did not worsen depression scores in children living with HIV and their caregivers in Ghana(2020)

Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality(2015)

Pediatric HIV Disclosure Intervention Improves Immunologic Outcome at 48 Weeks: The Sankofa Trial Experience(2023)

Sankofa Pediatric HIV Disclosure Intervention Did Not Worsen Depression Scores in Children Living with HIV and their Caregivers in Ghana(2020)

Tenofovir diphosphate concentrations in dried blood spots predict future HIV suppression but not virologic failure in adolescents with HIV(2025)

The geographical distribution of dialysis services in Ghana(2018)

State of Renal Replacement Therapy Services in Ghana(2015)

Global Dialysis Perspective: Ghana(2023)

Towards SDG3: Empowering Non-Nephrologists to Perform Peritoneal Dialysis in District Settings(2022)

Demography and Outcomes of End-Stage Renal Diseases (ESRD) of in Children Admitted to a Renal Unit in a Teaching Hospital in Kumasi, Ghana.(2022)

Pediatric kidney replacement therapies in low-to-middle income countries: a review and white paper(2025)

Malnutrition: Missed opportunities for diagnosis(2009)

Rural and semi-urban differences in salt intake, and its dietary sources, in Ashanti, West Africa.(2005)

Assessment and Management of Severe Malnutrition in Children(2011)

The role of nutritional status on follow-up among HIV-infected children at a teaching hospital clinic in Ghana(2016)

Assessment and Management of Severe Malnutrition in Children Evaluation Et Gestion De La Malnutrition Chez Les Enfants(2011)

Public Health Implications of Household Water Sources in the Kumasi Metropolis, Ghana. A Case Study(2023)

Investigating Household Water Quality Concerns in Kumasi, Ghana: Health Risks and Potential Implications: A Case Study(2025)

Pharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection(2015)

Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection(2016)

Evaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations(2018)

Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis(2022)

Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children(2017)

Global Estimates and Determinants of Antituberculosis Drug Pharmacokinetics in Children and Adolescents: A Systematic Review and Individual Patient Data Meta-Analysis(2022)

Paediatric tuberculosis at the national teaching hospital CNHU-HKM of Cotonou, Benin: a retrospective study.(2011)

Reply to: Observations on malnutrition and anti-TB drugs in Ghana(2021)

Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis(2017)

Paediatric nephrology in under-resourced areas(2021)

Structures, Organization, and Delivery of Kidney Care to Children Living in Low-Resource Settings(2024)

Effect of malnutrition on the pharmacokinetics of anti-TB drugs in Ghanaian children(2021)

The unacknowledged impact of urinary schistosomiasis in children: 5 cases from Kumasi, Ghana(2015)

Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study(2022)

Association Between Perfluoroalkyl Substance Exposure and Renal Function in Children With CKD Enrolled in H3Africa Kidney Disease Research Network(2019)

Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study(2021)

Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy(2022)

Hydrogen Sulfide as a Potential Therapy for COVID-19-Associated Nephropathy(2023)

Urine dipstick as a screening test for urinary tract infection(2008)

Pelvi-Ureteric Junction Obstruction at Red Cross Children's Hospital, Cape Town: a Six Year Review.(2014)

PREVALENCE, DETECTION, MANAGEMENT AND CONTROL OF HYPERTENSION IN ASHANTI, WEST AFRICA(2004)

Population pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing(2019)

Effect of Rifampin-Isoniazid-Containing Antituberculosis Therapy on Efavirenz Pharmacokinetics in HIV-Infected Children 3 to 14 Years Old(2018)

Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection(2021)

Adequacy of WHO weight-band dosing and fixed-dose combinations for the treatment of TB in children(2023)

Effect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old(2019)

Pharmacokinetics of Tenofovir Diphosphate, Lamivudine Triphosphate and Emtricitabine Triphosphate in Adolescents With HIV Infection With and Without Tuberculosis Coinfection(2025)

Pharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg(2023)

Disaster preparedness and kidney health in children(2025)

Detect early, protect kidney health: World Kidney Day 2025(2025)

RURAL AND SEMI-URBAN DIFFERENCES IN SALT INTAKE, AND ITS DIETARY SOURCES,(2005)

Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana(2018)

Hearing Loss in Chronic Kidney Disease(2021)

Clean water to prevent kidney disease(2020)

Hearing loss in patients with chronic kidney disease and psychological burden in their caregivers(2019)

A typical Kawasaki syndrome in COVID-19 infection: a case report of a multisystem inflammatory syndrome in a child (MIS-C)(2021)

Audit of posterior urethral valve (PUV) in children at Red Cross Children Hospital, Cape Town, January 2002 - January 2009(2009)

WCN24-1361 COMPLETE PENOSCROTAL TRANSPOSITION AND ASSOCIATED ANOMALIES IN A NEWBORN(2024)

Annual Congress of the Chinese Blood Purification Center Administration Committee. September 25-28, 2014, Guangzhou: Abstracts(2015)

Correction: Randomized Controlled Trial of RTS,S/AS02Dand RTS,S/AS01EMalaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children(2010)

Sankofa Pediatric HIV Disclosure Intervention Did Not Worsen Depression Scores in Children Living with HIV and their Caregivers in Ghana(2020)

Pediatric nephrology in under-resourced areas: one pill will not cure all ills—economics and awareness are both important factors(2023)

Effect of HIV infection on plasma exposure to first-line TB drugs and target attainment in children(2023)

WCN24-1142 AN UNUSUAL CAUSE OF NEUROGENIC BLADDER IN A CHILD(2024)

The Africa hepatopancreatobiliary cancer consortium for the study of epidemiology, etiology, pathobiology of liver, biliary tract, and pancreatic cancers in Africa(2024)

The impact of deportation and disparities on pediatric kidney health: a humanitarian call to action(2025)

Evaluating intravascular hypovolaemia by manually assessing peripheral limb coolness compared with the capillary refill time in children aged <5 years in a tropical environment: a prospective cohort study of diagnostic accuracy(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.