Paul Poku Sampene Ossei

Pathology

About

Dr. Paul Poku Sampene Ossei is a Consultant Histo- and Forensic Pathologist and had his medical training at Kharkov Medical Academy from 1989 to 1995 in Ukraine, USSR. He obtained his Fellowship in Pathology at the UniKlinikum, Muenster, Germany in 2009. He is a Senior Lecturer and currently the Head of Department of Pathology, SMD, KNUST. He is the author of more than 30 scientific papers in high-quality peer-reviewed journals.

Research Summary

(inferred from publications by AI)

The researcher has conducted extensive research across diverse domains, focusing on integrating plant extracts for anti-inflammatory effects with neuroinflammation mechanisms, examining toxicological impacts on animals and plants, studying cellular repair mechanisms such as autophagy, and exploring bioactive compounds' natural defense mechanisms against diseases. Their work extends to broader societal health contexts, particularly in addressing chronic conditions like heart disease and alcohol use among Ghanaian residents, while also contributing to environmental impact assessments. This comprehensive approach underscores their commitment to advancing health sciences through interdisciplinary studies.

Research Themes

All Papers

Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin(2016)

<i>Lantana camara</i> leaf extract ameliorates memory deficit and the neuroinflammation associated with scopolamine-induced Alzheimer’s-like cognitive impairment in zebrafish and mice(2023)

Evaluation of Dermal Toxicity and Wound Healing Activity of Cnestis ferruginea Vahl ex DC(2022)

Antioxidant and in vivo Wound Healing Activities of Clausena anisata(2015)

Mucin expression patterns in histological grades of colonic cancers in Ghanaian population(2017)

Palmatine Attenuates Metastatic Lung Colonization of Triple Negative Breast Cancer Cells(2022)

Profile of suicide within the northern part of Ghana: A decade under review(2022)

Wound healing, antimicrobial and antioxidant properties of the leaf and stem bark of Entada africana Guill. & Perr.(2020)

Profile of unnatural mortalities in Northern part of Ghana; a forensic-based autopsy study(2019)

Iron-deficiency anaemia in children with congenital heart diseases at a teaching hospital in Ghana(2020)

Protective effects of andrographolide against diclofenac-induced gastric damage(2021)

Acute and sub-acute toxicity studies of the chloroform extract of Crinum asiaticum bulbs in mice.(2021)

Antitubercular activities of Crinum asiaticum bulb extract using aeroso-linduced Mycobacterium smegmatis in mice model(2022)

Anti-arthritic activity of solvent extracts of the bulbs of Crinum pedunculatum R.Br.(2022)

Formulation of Suppositories of Alum Produced from Bauxite Waste in Ghana for the Treatment of Hemorrhoid(2021)

Patterns and Presentation of Prostate Cancer in the Brong Ahafo Region of Ghana: A 6-Year Single Center Retrospective Study(2019)

Preliminary health risk assessment of two exudate gums as pharmaceutical excipients(2023)

An acute and sub-acute toxicological assessment of Reissantia indica plant extract in male Sprague-Dawley rats: Hematological, serum biochemical and histopathology(2024)

The hydroethanolic root extract of Psydrax subcordata (DC.) Bridson exhibits antinociceptive and anti-inflammatory effects in animal models(2022)

Total abdominal hysterectomy in a Tertiary Hospital in Kumasi: Indication, Histopathological Findings and Clinicopathological Correlation(2018)

Enucleation of a Giant Prostatic Hyperplasia in Ghana: A Case Report and Mini Literature Review(2018)

Reporting a Case with Literature Review on Enucleation of a Giant Prostatic Hyperplasia in Ghana(2021)

The Culture of Herbal Preparations Among Pregnant Women: A Remedy or a Suicide Potion? A Case Report and Mini Review(2020)

Outbreak of influenza a viral infection in Ghana: A consideration of autopsy findings and a mini-review of the literature(2019)

Review of gunshot fatalities in the Northern part of Ghana; a 6 year forensic autopsy based study(2019)

Prevalence of Venous Thromboembolism in Kumasi: A Postmortem-Based Study in a Tertiary Hospital in Ghana(2020)

Latent Medical Conditions of Drivers Involved in Road Traffic Collisions in Ghana: Implication from Autopsy Findings(2021)

Trend analysis and economic effect of RTA deaths on dependency ratio in Ghana(2019)

Beyond survival: unraveling the dynamics of Ebola virus resurgence in Sub-Saharan Africa and the remarkable journey of survivors(2023)

Anti-Arthritic Effect of the Hydroethanolic Root Extract of Psydrax subcordata in Rats(2022)

Nephroprotective Activity of Dialium guineense Aqueous Extract Against Cisplatin-Induced Kidney Damage in Rats(2024)

Protective effect of hydroethanolic leaves extract of Solanum macrocarpon on Cisplatin-induced kidney injury in rats(2024)

Death certificates errors in academic hospital; Review of 617 cases at Komfo Anokye Teaching Hospital (KATH), Kumasi(2017)

Detecting Ureaplasma urealyticum among HIV-infected women with or without human papillomavirus using real-time PCR with the ANYPLEX™ II STI-7 assay system(2019)

Health and Toxicity Effects of Solanum torvum and Solanum nigrum Berries Extract on Rats(2024)

Nuclear Localisation of Autophagic p62 and Associated Cytoplasmic Beclin-1 and Bcl-2 Expressions in Adenomas and Adenocarcinomas of the Colorectal Regions(2018)

COVID-19 Impact on Medical Practice in Sub-Saharan Africa; The Need to Guard Against Medical Negligence: A Case Report in a Health Care Facility in Kumasi, Ghana(2021)

Non-HDL Cholesterol and Remnant Cholesterol Predict Different Components of the Metabolic Syndrome in Type 2 Diabetes Mellitus Patients in a Regional Hospital(2023)

An Acute Toxicological Assessment of Reissantia Indica Plant Extract in Male Sprague-Dawley Rats: Hematological and Serum Biochemical(2023)

Determinants of Hospital Stay Duration Post-Colorectal Surgery(2024)

Hydroethanolic Leaves Extract of Amaranthus Cruentus Protects Against Lead-Induced Hepatorenal Toxicity in Rats(2024)

Suicidal Behavior in Police Custody: a Ten Year (2011-2021) Study in the Northern Part of Ghana(2025)

Diosgenin ameliorates silica‐induced tuberculosis in rats(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.