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Paul Buule

Civil Engineering

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Research Summary

(inferred from publications by AI)

This researcher focuses on advancing HIV-1 research within the life sciences domain, particularly examining treatment efficacy and immune correlates in viral dynamics. Their work explores themes of latency reversal, integrase inhibitor effects, and reservoir formation among HIV-1-infected individuals, with applications to public health strategies.

Research Themes

All Papers

Reduced HIV-1 latent reservoir outgrowth and distinct immune correlates among women in Rakai, Uganda(2020)
HIV-1 subtype A1, D, and recombinant proviral genome landscapes during long-term suppressive therapy(2024)
Reduced Frequency of Cells Latently Infected With Replication-Competent Human Immunodeficiency Virus-1 in Virally Suppressed Individuals Living in Rakai, Uganda(2017)
Effective and targeted latency reversal in CD4 <sup>+</sup> T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection(2024)
Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen(2024)
Association between HIV-1 Nef-mediated MHC-I downregulation and the maintenance of the replication-competent latent viral reservoir in individuals with virally suppressed HIV-1 in Uganda: an exploratory cohort study(2025)
Dating reservoir formation in virologically suppressed people living with HIV-1 in Rakai, Uganda(2023)
PP 1.30 – 00159 Dating HIV-1 reservoir formation in ARV-suppressed Ugandans(2022)
Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen(2023)
PP1.11 – 00021 Impact of HIV-1 Tat and TAR Sequence Diversity on Clinical and Reservoir Characteristics(2024)

Collaboration Network

No collaborations found in the dataset.

About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.