Michael Ntim

Physiology

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Research Summary

(inferred from publications by AI)

The researcher's work is centered on integrating biological biomarkers across various domains to develop effective strategies for cancer immunotherapy, health disparities, and chronic disease management. Their research spans multiple fields, including immunology, neuroscience, pharmacology, and public health, with a focus on understanding the role of biological markers in disease diagnosis, treatment, and prevention. Key themes include: 1. **Cancer Immunotherapy and Biomarkers**: Development of models like the immune score to predict prognosis using biomarkers. 2. **Biology and Health Disparities**: Investigating interactions between chronic diseases (e.g., hypertension) and factors affecting brain development. 3. **Neurogenesis and Ageing**: Exploring the role of neural connections in cognitive decline, supported by neurovascular insights. 4. **Global Health Policies and Public Health**: Considering interventions like task-shifting strategies to reduce hypertension. 5. **Autophagy and Pancreatic Cancer**: Addressing both promising benefits and potential controversies regarding autophagy's role in cancer. 6. **Neuroscience and Sleep Disorders**: Linking sleep patterns with brain health, influencing long-term cognitive outcomes. The researcher employs a holistic approach, using biomarkers as tools to enhance understanding and improve treatment options across these interconnected fields, aiming to contribute significantly to global health solutions.

Research Themes

All (38 Papers)

Health Sciences (20 Papers)

Life Sciences (14 Papers)

Social Sciences (4 Papers)

All Papers

An immune cell infiltration-based immune score model predicts prognosis and chemotherapy effects in breast cancer(2020)

Prediction of Survival Rate and Chemotherapy Effect by an Immune Score Model in Colorectal Cancer(2022)

Health insurance coverage with or without a nurse-led task shifting strategy for hypertension control: A pragmatic cluster randomized trial in Ghana(2018)

Training nurses in task-shifting strategies for the management and control of hypertension in Ghana: a mixed-methods study(2017)

A cluster-randomized trial of task shifting and blood pressure control in Ghana: study protocol(2014)

Application of the Consolidated Framework for Implementation Research to examine nurses’ perception of the task shifting strategy for hypertension control trial in Ghana(2020)

Exploring stakeholders’ perceptions of a task-shifting strategy for hypertension control in Ghana: a qualitative study(2017)

The landscape of immune cell infiltration and its clinical implications of pancreatic ductal adenocarcinoma(2020)

Long-term social isolation inhibits autophagy activation, induces postsynaptic dysfunctions and impairs spatial memory(2018)

Long-Term Social Isolation-Induced Autophagy Inhibition and Cell Senescence Aggravate Cognitive Impairment in D(+)Galactose-Treated Male Mice(2022)

Impaired Cognitive Function and Altered Hippocampal Synaptic Plasticity in Mice Lacking Dermatan Sulfotransferase Chst14/D4st1(2019)

The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway(2021)

Effect of emodin on long non‐coding RNA‐mRNA networks in rats with severe acute pancreatitis‐induced acute lung injury(2021)

Reducing Nav1.6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription(2022)

SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice(2020)

TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway(2020)

Treatment with Bifidobacteria can suppress Aβ accumulation and neuroinflammation in APP/PS1 mice(2020)

AQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized Expression of AQP4 Protein in Astrocytic Endfeet at the Blood–Brain Barrier(2022)

Sub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section — a randomized control trial(2019)

Sustaining Nurse‐Led Task‐Shifting Strategies for Hypertension Control: A Concept Mapping Study to Inform Evidence‐Based Practice(2017)

‘I believe high blood pressure can kill me:’ using the PEN-3 Cultural Model to understand patients’ perceptions of an intervention to control hypertension in Ghana(2017)

OC05_01 Task-Shifting for the Management of Hypertension: Lessons From the Global Alliance for Chronic Diseases(2016)

IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes(2018)

TIP60 buffers acute stress response and depressive behaviour by controlling PPARγ-mediated transcription(2022)

Cell-type-specific expression of Nav1.6 in the developing brain of mice and its involvement in glial activation in Alzheimer’s disease(2025)

Bacteriological Profile and Predictors of Death Among Neonates With Blood Culture-Proven Sepsis in a National Hospital in Tanzania—A Retrospective Cohort Study(2022)

Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice(2022)

SRC-1 Deficiency Increases Susceptibility of Mice to Depressive-Like Behavior After Exposure to CUMS(2021)

[LB.03.07] COMPARATIVE EFFECTIVENESS CLUSTER-RANDOMIZED TRIAL OF A NURSE-LED TASK-SHIFTING STRATEGY FOR HYPERTENSION CONTROL VERSUS PROVISION OF HEALTH INSURANCE COVERAGE IN CHCS IN GHANA(2017)

Erratum to: Training nurses in task-shifting strategies for the management and control of hypertension in Ghana: a mixed-methods study(2017)

Phospholipase D2: A biomarker for stratifying disease severity in acute pancreatitis?(2025)

Predictors of postpartum depression among new mothers in Kumasi, Ghana: A multicenter study using Bayesian analysis(2025)

GPR50 Distribution in the Mouse Cortex and Hippocampus(2020)

TIP60 mediates stress-induced hypertension via promoting glutamate dmPFC- to- vCA1 release(2023)

Review of: "Auditing the Cost of Treating Hypertension in a Tertiary Health Facility in Yobe State, North-Eastern Nigeria"(2024)

Developing Culturally Salient Assessment Tools and Interventions for Underserved and High-Risk Populations in the United States and Africa(2024)

Editorial: Neurovascular health insights: a powerful tool to understand and prognose neurocognitive decline(2025)

Triglyceride-glucose index in predicting gastric cancer prognosis: A need for caution(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.