Kweku Bedu-Addo

Physiology

About

I was born on the 22nd of November 1961. I did my primary and secondary schools at Twedaase primar and Middle Schools. from. 1967-1974. I did my my secondary education at Swedru Secondary School from 1974-1981 where I obtained my O and A Level. I was then admitted to the Department of Biological Sciences, University of Science and Technology in 1982 where I obtained a BSc in Biological Sciences in 1987. I did my two year national service at the same department from September 1987-August 1989. I was appointed a teaching Assistant in the department from 1989-1990. i was admitted into the Mphil program of the Department in September 1990 and completed in June 1993. I was appointed a Lecturer in the Department of Physiology, School of Medical Sciences in September 1993 where I taught various aspects of physiology to undergraduate and postgraduate students. I gained admission to the Department of Biological Sciences of the University of Birmingham, UK in 2001 and obtained a PhD in Biological Sciences. I resumed duty at the Department of Physiology, Kwame Nkrumah University of Sciences and Technology in September 2006 where I have remained till now. I have served the school in various capacities. I have been Head of Physiology and head of Sonography at the University. I have been an exam officer at the Department of Physiology and school of Medical Sciences.

Research Summary

(inferred from publications by AI)

The researcher has conducted extensive work focusing on energy expenditure, metabolic health, reproductive biology, genetics, and environmental effects on health outcomes across diverse populations. Key findings include increased daily energy expenditure linked to obesity development in later life, with diet and activity levels significantly influencing metabolic profiles during early adulthood. Sleep length was found to affect sperm production rates, while genetic elements such as the tumor suppressor protein p53 are implicated in disease progression associated with various health conditions. Environmental factors have also been shown to impact metabolic risks across multiple populations, highlighting their critical role in public health interventions and research.

Research Themes

All Papers

Daily energy expenditure through the human life course(2021)

Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure(2023)

A standard calculation methodology for human doubly labeled water studies(2021)

The human microbiota is associated with cardiometabolic risk across the epidemiologic transition(2019)

Physical activity and fat-free mass during growth and in later life(2021)

8513 Toxic Metals Are Associated With Increased Diabetes And Obesity Through Gut Microbiota Changes In Five African-Origin Populations(2024)

Toxic Metals Impact Gut Microbiota and Metabolic Risk in Five African-Origin Populations(2024)

Energy compensation and adiposity in humans(2021)

Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition(2022)

Energy expenditure and obesity across the economic spectrum(2025)

Utility of silhouette showcards to assess adiposity in three countries across the epidemiological transition(2022)

Objectively measured moderate-to-vigorous physical activity does not attenuate prospective weight gain among african-origin adults spanning the epidemiological transition(2025)

Utility of silhouette showcards to assess adiposity in three countries across the epidemiological transition(2020)

Objectively measured moderate-to-vigorous physical activity does not attenuate prospective weight gain among African-origin adults spanning the epidemiological transition.(2024)

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study(2023)

Gut microbiota, short chain fatty acids, and obesity across the epidemiologic transition: the METS-Microbiome study protocol(2018)

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study(2023)

The human microbiota is associated with cardiometabolic risk across the epidemiologic transition(2019)

FRI010 Human Gut Microbiota And Metabolic Profiles Are Associated With Obesity In Five African-Origin Populations(2023)

Abstract P071: Metabolic Syndrome Gut Microbial Associations Are Independent Of Country Of Origin: Evidence From African-origin Populations(2021)

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study(2023)

Variation in human water turnover associated with environmental and lifestyle factors(2022)

Heat Adaptation Benefits for Vulnerable groups In Africa (HABVIA): A study protocol for a controlled clinical heat adaptation trial(2024)

Heat Adaptation Benefits for Vulnerable groups In Africa (HABVIA): a study protocol for a controlled clinical heat adaptation trial(2025)

Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake(2025)

Author Correction: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake(2025)

Counting sperm does not add up any more: time for a new equation?(2007)

Mobilisation of stored calcium in the neck region of human sperm a mechanism for regulation of flagellar activity(2008)

Bicarbonate and bovine serum albumin reversibly ‘switch’ capacitation-induced events in human spermatozoa(2005)

Semen parameters and the incidence and effects of bacteriospermia in male partners of infertile couples attending a fertility clinic in the Kumasi Metropolis, Ghana(2018)

Characterization of the Ca2+ Channels Involved in the Progesterone-Induced Ca2+ Influx and Acrosome Reaction (AR) in Human Spermatozoa(2009)

Potassium ions Improve the Progesterone-Induced [Ca2+]I Increase and Acrosome Reaction as well as the Potassium-Induced [Ca2+]I Increase in Human Spermatozoa(2010)

Acquisition of the progesterone induced [Ca 2+ ] i signal in capacitating human spermatozoa(2004)

Total Round Cell Concentration in Semen and Its Association With Sperm DNA Fragmentation Index Among Ghanaian Males in Kumasi(2025)

Patterns of [Ca2+]i mobilization and cell response in human spermatozoa exposed to progesterone(2006)

Variability in energy expenditure is much greater in males than females(2022)

Gut microbiota alterations in response to sleep length among African-origin adults(2021)

An ecological analysis of sleep health across five African-origin populations spanning the epidemiologic transition(2025)

Prevalence, placenta development, and perinatal outcomes of women with hypertensive disorders of pregnancy at Komfo Anokye Teaching Hospital(2020)

Prevalence and associated factors of fetal macrosomia in a rural community in Ghana(2020)

Prevalence, Placenta Development, and Perinatal Outcomes of Women with Hypertensive Disorders of Pregnancy at Komfo Anokye Teaching Hospital(2020)

Diagnostic Accuracy of Urine Microalbumin and Serum Uric Acid: A Case-control Study of Patients with Preeclampsia in the Komfo Anokye Teaching Hospital, Kumasi, Ghana(2018)

The Analysis of bcl-2 in Association with p53 and Ki-67 in Triple Negative Breast Cancer and Other Molecular Subtypes in Ghana(2021)

Expression profile of tumour suppressor protein p53 and its regulator MDM2 in a cohort of breast cancer patients in a Tertiary Hospital in Ghana(2021)

Expression of Tumour-Associated MUC1 Is a Poor Prognostic Marker in Breast Cancer in Kumasi, Ghana(2020)

Consumption of Monounsaturated Fatty Acids Is Associated with Improved Cardiometabolic Outcomes in Four African-Origin Populations Spanning the Epidemiologic Transition(2021)

Low birth weight among adolescents at Cape Coast Metropolitan Hospital of Ghana(2016)

Abnormal spirometric patterns and respiratory symptoms in HIV patients with no recent pulmonary infection in a periurban hospital in Ghana(2024)

Abnormal spirometric patterns and respiratory symptoms in HIV patients with no recent pulmonary infection in a periurban hospital in Ghana(2022)

Breast lesions and cancer: histopathology and molecular classification in a referral hospital in Ghana(2021)

Alcohol consumption and HIV disease prognosis among virally unsuppressed in Rural KwaZulu Natal, South Africa(2023)

Analysis of p21 Expression in Cervical Carcinoma at a Tertiary Institution in Ghana: An Immunohistochemical Study(2023)

Analysis of p21expression in cervical carcinoma in a tertiary institution in Ghana: an immunohistochemical study(2022)

Immunohistochemical profiling of Bcl-2 and EGFR proteins in cervical carcinoma at a tertiary hospital in Ghana(2024)

Association Between Alcohol Consumption and Blood Pressure Levels Among HIV Sero-Positive and Sero-Negative Cohorts: A Secondary Analysis of the Vukuzazzi Study(2024)

Asymptomatic peripheral arterial disease in HIV patients in Ghana: A case-control study(2023)

Decline in Isotope Dilution Space Ratio Above Age 60 Could Affect Energy Estimates Using the Doubly Labeled Water Method(2024)

The relationship between leptin-to-adiponectin ratio and HOMA-IR and metabolic syndrome in five African-origin populations(2024)

The utility of physical activity questionnaires among African origin populations; lost in translation?(2024)

Toxic metals impact gut microbiota and metabolic risk in five African-origin populations(2025)

Effect of Environmental Factors, Lifestyle, Lipid Profile and Previous Medical Conditions on Semen Quality in Male Partners of Infertile Couples; Evidence from Kumasi Metropolis(2016)

Greater male variability in daily energy expenditure develops through puberty(2023)

Expression profile of tumour suppressor protein p53 and its regulator MDM2 in a cohort of breast cancer patients in a Tertiary Hospital in Ghana(2021)

P14-066-23 Dietary Patterns Identified Through DNA Metabarcoding and Their Association With Geographic Location and Health Indicators(2023)

Silhouette showcards confirm altered obesity-associated body image perception in international cohort study of African-origin populations(2024)

Breast lesions and cancer: histopathology and molecular classification in a referral hospital in Ghana(2021)

Analysis of the Histopathological Characteristics and Expression of RIPK1 and NF- κB in Cervical Cancer in Kumasi, Ghana(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.