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John Asiedu Larbi

Theoretical and Applied Biology

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About

John A. Larbi is an Associate Professor in the Department of Theoretical and Applied Biology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. He holds a PhD degree in Biological Sciences with expertise in Parasitology and Immunology. He is a DAAD scholar having won a scholarship (Sandwich) from the German Academic Exchange Service to undertake his PhD at the Bernhard Nocht Institute for Tropical Medicine and Hygiene/University of Hamburg in Germany and KNUST. He had his bachelor’s degree in Biological Sciences as well as an MPhil Biological Sciences (Parasitology) degree at the KNUST.He has several years of experience in teaching and research. His research interest focuses on infectious parasitic diseases of public health importance. He is particularly interested in epidemiology of parasitic infections in children and wildlife [notably, Soil transmitted helminths, filarial worms and other Neglected Tropical Diseases (NTDs)], genetic diversity of zoonotic parasites, host-parasite interactions including immune and inflammatory responses, as well as parasite ecology. He also has an interest in water quality, vector-borne diseases, risk assessment and infection control. He has collaborated with both local and international researchers especially in postgraduate training of research students. Prior to becoming a lecturer he had worked at the Kumasi Centre for Collaborative Research (KCCR) on the filariasis projects as an Assistant researcher, then a research scientist, and then held the position of Head of Laboratories (acting; 2004-2006) at the KCCR; a state-of-the-art research facility in Kumasi.Prof. J. A. Larbi has served on a number of committees and boards, and is currently the Vice Dean, Faculty of Biosciences, College of Science, KNUST. He has authored and co-authored many impactful scientific articles published in reputable journals.

Research Summary

(inferred from publications by AI)

The researcher has conducted extensive research across a diverse range of themes, including parasitic diseases, lymphatic system studies, tick-borne infections, malarism, plant studies, infectious disease research, and public health initiatives. Their work focuses on neglected tropical diseases (NTDs), particularly parasitic infections such as Onchocerciasis, Malaria, and parasites like Plasmodium falciparum. The researcher has explored the effectiveness of treatments for these diseases, emphasizing approaches tailored to prevent disease transmission and control parasitic infections in neglected zones. They have also contributed to understanding neglected tropical diseases through studies on tick-borne pathogens, rickettsias, and Coxiella species. The research highlights the importance of public health interventions to manage these diseases effectively while considering the challenges posed by environmental restoration efforts.

Research Themes

All Papers

Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study(2007)
Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis)(2002)
Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin(2006)
Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study(2008)
Doxycycline Reduces Plasma VEGF-C/sVEGFR-3 and Improves Pathology in Lymphatic Filariasis(2006)
T Regulatory-1 Cells Induce IgG4 Production by B Cells: Role of IL-10(2005)
Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children(2013)
Variation in exposure to Anopheles gambiae salivary gland peptide (gSG6-P1) across different malaria transmission settings in the western Kenya highlands(2012)
Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands(2012)
Malaria Knowledge-Base and Prevalence of Parasitaemia in Asymptomatic Adults in the Forest Zone of Ghana(2022)
Prevalence of Plasmodium falciparum gametocytaemia in asymptomatic school children before and after treatment with dihydroartemisinin-piperaquine (DP)(2023)
Prevalence Rate and Contributory Factors of Malaria in the Amenfi West District, Ghana(2017)
Asymptomatic Malaria Prevalence and Health Facility Influence on the Attitude of Facility Users in Malaria Meso-Endemic Districts in Ghana(2021)
Liana species richness, abundance and relationship with trees in the Bobiri forest reserve, Ghana: Impact of management systems(2009)
Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015(2019)
Modeling the die-off of E. coli and Ascaris in wastewater-irrigated vegetables: implications for microbial health risk reduction associated with irrigation cessation(2013)
Seasonal Disparity in Microbial and Soil Transmitted Helminths Concentrations in Irrigation Samples(2018)
Molecular survey of Anaplasma and Ehrlichia species in livestock ticks from Kassena-Nankana, Ghana; with a first report of Anaplasma capra and Ehrlichia minasensis(2023)
Occurrence of Rickettsia spp. and Coxiella burnetii in ixodid ticks in Kassena-Nankana, Ghana(2023)
First record of Rhipicephalus (Boophilus) microplus in Ghana, a potential risk to livestock production(2023)
First molecular identification of multiple tick-borne pathogens in livestock within Kassena-Nankana, Ghana(2023)
First record of <i>Babesia</i> and <i>Theileria</i> parasites in ticks from <scp>Kassena‐Nankana</scp> , Ghana(2023)
Molecular Detection of Tick‐Borne Pathogens in Kumasi: With a First Report of Zoonotic Pathogens in Abattoir Workers(2024)
<i>Toxoplasma gondii</i> among pregnant women attending antenatal care in a district hospital in Ghana(2023)
Ticks and tick‐borne pathogens in selected abattoirs and a slaughter slab in Kumasi, Ghana(2024)
Spatial and Seasonal Patterns of Tick Infestations in Kassena‐Nankana Livestock(2024)
Molecular identification of Crimean-Congo haemorrhagic fever virus in Hyalomma rufipes and Amblyomma variegatum in the Upper East Region of Ghana(2024)
Author response for "Ticks and tick‐borne pathogens in selected abattoirs and a slaughter slab in Kumasi, Ghana"(2024)
Author response for "Ticks and tick‐borne pathogens in selected abattoirs and a slaughter slab in Kumasi, Ghana"(2024)
Incidence, prevalence and severity of fall armyworm infestation in Ghana: a case of two maize enclaves in the Ashanti Region of Ghana(2024)
Zoonotic Gastrointestinal Parasites of Baboons (<i>Papio anubis</i>) in the Shai Hill Reserve in Ghana(2020)
Distribution of intestinal parasites of baboons ( <i>Papio anubis</i> ) and warthogs ( <i>Phacochoerus aethiopicus</i> ) at the Mole National Park, Ghana(2020)
Logging effects on parasitic infections in a swamp rat (<i>Malacomys edwardsi</i>) in West Africa(2021)
Burdens of <i>Ascaris</i> spp. and <i>Cryptosporidium</i> spp. parasites in farm pigs in Ghana(2022)
Author response for "Burdens of Ascaris spp. and Cryptosporidium spp. parasites in farm pigs in Ghana"(2021)
Microbial Quality of Some Fresh-Cut Ready-to-Eat Fruits Sold in Some Markets and Bus Terminals in the Kumasi Metropolis, Ghana(2023)
Clinical, Hematological and Histopathological Responses to Arsenic Toxicity in ICR Mice Using Arsenic Levels Synonymous to Buruli Ulcer EndemicCommunities in the Amansie West District of Ghana(2012)
Susceptibility of Arsenic-Exposed ICR Mice to Buruli Ulcer Development(2013)
Presence of Chlamydia Infection among asymptomatic Female Commercial Sex-workers (CSWs) in the Kumasi Metropolis, Ghana(2016)
A probabilistic assessment of the contribution of wastewater-irrigated lettuce to Escherichia coli O157:H7 infection risk and disease burden in Kumasi, Ghana(2014)
Recreational Water Quality Assessment of Some Selected Swimming Pools in the Asuogyaman District, Ghana(2019)
Detection of <i>Leishmania</i> DNA in Phlebotomine Sand Flies in Tsatee, a Community in the Volta Region, Ghana(2023)
The effectiveness of albendazole against hookworm infections and the impact of bi-annual treatment on anaemia and body mass index of school children in the Kpandai district of northern Ghana(2024)
Malaria and helminths co‐infection—Effects on anaemia, iron and folate deficiencies in paediatric population in Ghana(2025)
Malnutrition and intestinal parasitic infections: a cross‑sectional survey of hospitalized malnourished children in the Kumasi Metropolis, Ghana(2025)
Intestinal Parasitic Infections in Ghana: A Review of Infections and the Risk of Zoonotic Transmission(2025)
Association Between Alcohol Consumption and Blood Pressure Levels Among HIV Sero-Positive and Sero-Negative Cohorts: A Secondary Analysis of the Vukuzazzi Study(2024)
Implication of Urban and Peri-Urban Agricultural Wastewater Irrigation to Malaria Transmission in Kumasi(2018)
Microbial and Chemical Risk Assessment of River Bukuruwa Used as Drinking Water by Farming Communities(2018)
Filth Flies As Carriers of Intestinal Parasites And Fungi in a Tertiary Institution in Ghana(2022)
The effect of intermittent preventive treatment using sulphadoxine pyrimethamine in the control of malaria in pregnancy: A cross-sectional study in the Offinso district of Ghana(2010)
Missed opportunities for the diagnosis of pulmonary tuberculosis - polymerase chain reaction: A better tool(2014)
Missed Opportunities for the Diagnosis of Pulmonary Tuberculosis in Ashanti and Western Regions of Ghana; Polymerase Chain Reaction, A Better Tool(2013)
Temporal Relationship of Environmental Arsenic and M. ulcerans Infection in the Amansie West District(2013)
The Efficacy of Albendazole against Soil-Transmitted Helminths and the Impact of Mass Drug Administration of Albendazole and Ivermectin on Health Status(2016)
Microbial quality analysis in cocoa processing(2018)
Author response for "Distribution of intestinal parasites of baboons ( &lt;i&gt;Papio anubis&lt;/i&gt; ) and warthogs ( &lt;i&gt;Phacochoerus aethiopicus&lt;/i&gt; ) at the Mole National Park, Ghana"(2020)
Author response for "Distribution of intestinal parasites of baboons ( &lt;i&gt;Papio anubis&lt;/i&gt; ) and warthogs ( &lt;i&gt;Phacochoerus aethiopicus&lt;/i&gt; ) at the Mole National Park, Ghana"(2020)
Author response for "Distribution of intestinal parasites of baboons ( &lt;i&gt;Papio anubis&lt;/i&gt; ) and warthogs ( &lt;i&gt;Phacochoerus aethiopicus&lt;/i&gt; ) at the Mole National Park, Ghana"(2020)
Double Jeopardy in Malaria Infected Children with Common Haemoglobinopathies: A Cross-sectional Study in Malaria Mesoendemic Districts of Ghana(2022)
PA-609 Pre-established plasmodium falciparum clearance by artemether-lumefantrine (AL) versus artemether-lumefantrine (AL) + atovaquone-proguanil (AP) in mosquito vectors – a study within the ASAAP project(2023)
Mosquito Control Strategies and Insecticide Resistance of the Malaria Vector in Urbanized Land Use Types in Suame Municipality, Ghana(2024)
Total Round Cell Concentration in Semen and Its Association With Sperm DNA Fragmentation Index Among Ghanaian Males in Kumasi(2025)
Field testing of <i>Carica papaya</i> and <i>Zanthoxylum zanthoxyloides</i> extracts against fall armyworm ( <i>Spodoptera frugiperda</i> ) on maize plants(2025)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.