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Eric Boakye-Gyasi

Pharmacology

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About

Prof. Boakye-Gyasi, a recipient of the KNUST Vice Chancellor’s staff development scholarship programme in 2006, holds a B.Pharm (Hons) degree and a PhD (Pharmacology) from Kwame Nkrumah University and Technology (KNUST), Kumasi. He is an old student of Presbyterian Boys’ Secondary School, Legon-Accra.He has been a registered Pharmacist since 2007 and an active member of the Pharmaceutical Society of Ghana. He also holds membership with the Society for Medicinal Plant and Natural Product Research, the West African Society for Pharmacology (WASP) and the West African Network of Natural Products Research Scientists (WANNPRES).Prof. Boakye-Gyasi’s main research focus is on neuropharmacology of natural products – particularly in the areas of nociception and inflammopharmacology. He has over forty three (43) peer-reviewed articles with 774 citations, h-index of 16 and i10 index of 28 according to google scholar (as at 06/10/2021).Prof. Boakye-Gyasi was part of a team awarded USD 9,923.00 under the Building Stronger Universities Phase Two (BSUII) work Package Three (WP3) program to conduct a three month pilot study on “SAFE WATER FOR GOOD HEALTH” in 2016. As the principal investigator for a team, he received a grant of GHC 30,000 from the KNUST Research Fund (KReF) in January, 2019.He has served the university and the community in a number of capacities including but not limited to being the College Representative for the University Strategic Plan Implementation Oversight Committee (2017-2020), the Vice Chairman of Academic, Social and Research Pharmacists’ Association of the Pharmaceutical Society of Ghana from 2016 to 2018 and an astute reviewer for a number of international journals.Prof. Eric Boakye-Gyasi is currently the Associate On-line Editor for the Journal of Science and Technology (JUST) as well as the Coordinator for Postgraduate studies and Seminars in the Faculty of Pharmacy and Pharmaceutical Sciences and a member of the KNUST Vaccine Development and Production committee.

Research Summary

(inferred from publications by AI)

The researcher's work spans a wide range of topics in life sciences and pharmacology, encompassing both classical and modern research approaches. Their studies focus on the pharmacological effects of natural compounds, particularly examining how substances like xylopic acid influence biological processes such as inflammation, pain alleviation, neurotransmission, and neuroprotection. Additionally, their work delves into the traditional uses of plants, with a significant emphasis on Ficus species, including Fucus exasperata, which is evaluated for its anti-inflammatory and antipyretic properties. The researcher also investigates the bioactive properties of compounds like xylitol and xylopic acid in various contexts, such as murine models of neuropathic pain, HIV/AIDS prevention, and mental health interventions. Their research highlights a comprehensive understanding of drug mechanisms across diverse diseases, from traditional plant chemistry to pharmacology, with a focus on both classical studies and modern approaches.

Research Themes

All Papers

Analgesic effects of an ethanol extract of the fruits of Xylopia aethiopica (Dunal) A. Rich (Annonaceae) and the major constituent, xylopic acid in murine models(2012)
Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain(2014)
Analgesic Effects of an Ethanol Extract of the Fruits of Xylopia aethiopica and Xylopic Acid in Murine Models of Pain: Possible Mechanism(s)(2013)
Effects of an ethanol extract and the diterpene, xylopic acid, of <i>Xylopia aethiopica</i> fruits in murine models of musculoskeletal pain(2016)
Neuropharmacological effects of an ethanolic fruit extract of Xylopia aethiopica and xylopic acid, a kaurene diterpene isolate, in mice.(2014)
Xylopia aethiopica ethanolic fruit extract exhibits antidepressant-like effect in mice via interaction with serotonergic neurotransmission(2014)
An Evaluation of the Anti-inflammatory, Antipyretic and Antinociceptive Effects of Ficus exasperata (Vahl) Leaf Extract(2009)
Xylopia aethiopica fruit extract exhibits antidepressant-like effect via interaction with serotonergic neurotransmission in mice(2016)
Anxiolytic and Antidepressant Effects of a Leaf Extract of Palisota hirsuta K. Schum. (Commelinaceae) in Mice(2009)
Anticonvulsant activity of Pseudospondias microcarpa (A. Rich) Engl. hydroethanolic leaf extract in mice: The role of excitatory/inhibitory neurotransmission and nitric oxide pathway(2017)
Acetic acid‐induced colitis modulating potential of total crude alkaloidal extract of <i>Picralima nitida</i> seeds in rats(2023)
The crude alkaloidal extract of Picralima nitida seeds alleviates TNBS-induced inflammatory bowel disease through reduced serum expression of TNF-α, IL-1β and p38 MAPK(2024)
Attenuation of Anxiety Behaviours by Xylopic Acid in Mice and Zebrafish Models of Anxiety Disorder(2018)
Antiarthritic and antioxidant effects of the leaf extract of<i>Ficus exasperata</i>P. Beauv. (Moraceae)(2010)
An evaluation of the anti-inflammatory, antipyretic and analgesic effects of hydroethanol leaf extract of<i>Albizia zygia</i>in animal models(2016)
Preliminary Phytochemical Screening and In vitro Antioxidant Prop- erties of Trichilia monadelpha (Thonn.) J. J. de Wilde (Meliaceae)(2013)
Effects of Trichilia monadelpha (Meliaceae) extracts on bone histomorphology in complete Freund's adjuvant-induced arthritis(2017)
Effect of Trichilia monadelpha (Thonn.) J. J. De Wilde (Meliaceae) Extracts on Haematology, Cytokines and Oxidative Stress Biomarkers in Rats Adjuvant-Induced Arthritis(2015)
Anti-Arthritic Effects of Palisota hirsuta K. Schum. Leaf Extract in Freund’s Adjuvant-Induced Arthritis in Rats(2009)
Antinociceptive effects of a hydroethanolic stem bark extract of Burkea africana(2022)
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models(2017)
Possible mechanisms involved in the anti-nociceptive effects of hydro-ethanolic leaf extract of <i>Ziziphus abyssinica</i>(2017)
Analgesic Effect of Ziziphus abyssinica Involves Inhibition of Inflammatory Mediators and Modulation of KATP Channels, Opioidergic and Nitrergic Pathways(2021)
An isobolographic analysis of the anti-nociceptive effect of geraniin in combination with morphine or diclofenac(2017)
Geraniin attenuates Naloxone-Precipitated Morphine Withdrawal and Morphine-Induced Tolerance in Mice(2017)
Acute and sub-acute oral toxicity assessment of the aqueous extract from the aerial parts of Phyllanthus muellerianus (Kuntze) Exell. in rodents(2018)
Effect of Diclofenac and Andrographolide Combination on Carrageenan-Induced Paw Edema and Hyperalgesia in Rats(2022)
Pharmacognostic evaluation of three Apocynaceae plants that share the same West African local names(2021)
Predictors of medication nonadherence among hypertensive clients in a Ghanaian population: Application of the Hill‐Bone and Perceived Barriers to Treatment Compliance Scale(2022)
Fast-onset effects of Pseudospondias microcarpa (A. Rich) Engl. (Anacardiaceae) hydroethanolic leaf extract on behavioral alterations induced by chronic mild stress in mice(2023)
Anti-Inflammatory and antipyretic effects of an ethanolic extract of Palisota hirsuta K. Schum roots(2008)
Anti-Nociceptive Effects and the Mechanism of Palisota hirsuta K. Schum. Leaf Extract in Murine Models(2009)
Anti-inflammatory and Antipyretic Effects of an Ethanolic Extract of Capparis erythrocarpos Isert Roots(2011)
Anti-arthritic Effects of an Ethanolic Extract of Capparis erythrocarpos Isert Roots in Freund’s Adjuvant-induced Arthritis in Rats(2011)
Antipleuritic and Vascular Permeability Inhibition of the Ethyl Acetate-Petroleum Ether Stem Bark Extract of<i>Maerua angolensis</i>DC (Capparaceae) in Murine(2018)
Comparative Effect of Different Extracts and Fractions From Lophira Lanceolata Tiegh. Ex Keay (Ochnaceae) Leaves on Arterial Blood Pressure and Heart Rate in Anaesthetized Cats(2015)
Anti-inflammatory and analgesic effects of ethanolic leaf extract of Newbouldialaevis (P. Beauv.) Seemann Ex Bureau (Bignoniaceae)(2013)
Quality Control and Anti-Inflammatory Activity of the Stem Bark of Chlorophora regia A. Chev. (Moraceae)(2021)
Anti-arthritic and antioxidant properties of the ethanolic stem bark extract of Newbouldia laevis (P. Beauv.) Seaman ex Bureau (Bignoniaceae)(2008)
Further studies on the anti-nociceptive and anti-inflammatory effects of the aerial parts of Hilleria latifolia (Lam.) H. Walt.(2014)
The hydroethanolic root extract of Psydrax subcordata (DC.) Bridson exhibits antinociceptive and anti-inflammatory effects in animal models(2022)
Toxicological Assessment of<i> Pseudospondias microcarpa</i> (A. Rich.) Engl. Hydroethanolic Leaf Extract in Rats: Haematological, Biochemical, and Histopathological Studies(2018)
An isobolographic analysis of the antinociceptive effect of xylopic acid in combination with morphine or diclofenac(2015)
Hydroethanolic Stem Bark Extract of <i>Burkea africana</i> Attenuates Vincristine-Induced Peripheral Neuropathy in Rats(2020)
Neuro-therapeutic effect of ursolic acid in a murine model of vincristine-induced neuropathic pain(2025)
Anxiogenic-like Effects of a Root Extract of Sphenocentrum jollyanum Pierre in Murine Behavioural Models(2009)
Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) root extract exhibits anti-nociceptive and antipyretic activities in murine models(2017)
Antinociceptive Effects of an Ethanolic Extract of Capparis erythrocarpos Isert Roots in the Mice Formalin Test(2009)
Anticonvulsant effect of the hydroethanolic leaf extract of Psydrax subcordata (DC.) Bridson in murine models(2017)
Antidepressant-Like Effects of an Ethanolic Extract of Sphenocentrum jollyanum Pierre Roots in Mice(2008)
Regulation of Nrf2 and NF-κB activities may contribute to the anti-inflammatory mechanism of xylopic acid(2022)
Pseudocedrela kotschyi limits airway inflammation in ovalbumin-induced asthma in guinea pigs(2021)
Neuroprotective effects of xylopic acid on lipopolysaccharide-induced neuroinflammation(2015)
Prevalence and Predictors of Mother-to-Child Transmission of Human Immunodeficiency Virus (HIV) among HIV-exposed Infants(2025)
Effectiveness of Highly Active Anti-retroviral Therapy (HAART) in the Adult Population in the Ashanti Region of Ghana(2021)
HAART Therapy in Ghana: Assessment of Adverse Drug Reaction Reports of Patients at an HIV Clinic and a Teaching Hospital(2017)
ETHANOL ROOT EXTRACT OF THE AFRICAN APHRODISIAC, MONDIA WHITIE (PERIPLOCACEAE), POSSESES ESTROGENIC ACTIVITY(2015)
Assessment of renal function in HIV patients on tenofovir-containing antiretroviral therapy in Ghana: a longitudinal study(2022)
Involvement of catecholaminergic and nitric oxide–cGMP pathways in the antidepressant-like effects of hydroethanolic leaf extract of Morinda Longiflora G. Don in Mice(2024)
Antidepressant-like effect of picralima nitida total crude alkaloidal fraction in mice(2025)
The impact of zinc and testosterone co-treatment on tumourigenesis in prostate cancer: a novel model(2025)
Antiangiogenic effects of the hydroethanolic root extract of Croton membranaceus in chick chorioallantoic membrane(2025)

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.