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Edwin Ferguson Laing

Molecular Medicine

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About

Edwin F. Laing is a Fellow of the Ghana College of Physicians (Laboratory Medicine Division). He is a Clincal Biochemist by training and employed as a Consultant Clinical Biochemist at the Komfo Anokye Teaching Hospital (KATH) and as an Associate Professor of Chemical Pathology at the Department of Molecular Medicine, School of Medicine and Dentistry, KNUST with over 30 years of university teaching, and research experience. He holds a Ph.D. in Biochemistry and Molecular Biology and an MSc. in Clinical Biochemistry both from the University of Leeds in the United Kingdom. He holds a Bachelor of Medicine and a Bachelor of Surgery (MB ChB) and a Bachelor of Science in Human Biology from the University of Science and Technology, Kumasi, Ghana. He obtained his Ordinary and Advanced Level Certificates at  Adisadel College, Cape Coast, Ghana.University administrative positions held by Edwin F. Laing include: Head, Department of Molecular Medicine, Head, Department of Sonography, Departmental Examinations Officer, Head : Departmental Curriculum Review Committee, School Examinations Officer, Member of the School Board and Member of the College Board.Positions held at KATH include Physician-In-Charge of the Wednesday Diabetes Clinic  which he started and Head of the Department of Clinical Biochemistry.He was a Member of the Faculty Board for Laboratory Physicians of the Ghana College of Physicians. He was also a Member of the Technical Advisory Committee on Clinical Trials (TAC-CT) for the Food and Drugs Authority (FDA), Ghana. He acted as a reviewer for the KNUST as well as College of Health Sciences Research Funds. Edwin F. Laing was nominated by the Medical and Dental Council of the Gambia (MDCG) to review accreditation documents of the American International University West Africa (AIUWA) in Biochemistry and Chemical Pathology.Edwin F. Laing’s area of research is Metabolic Medicine with a focus on Metabolic Syndrome, Insulin Resistance, Diabetes Mellitus, Thyroid function and Vitamin D metabolism. He has been teaching at both undergraduate and postgraduate levels of Medical and Paramedical programmes of KNUST. He has supervised over 30 student projects at all levels (BSc, MSc, MPhil, PhD) from the year 2000.  He was External Examiner for the Level 400 examinations in Chemical Pathology at the University of Ghana Medical School. He acted as assessor for promotion to an academic position for one University in Ghana.Edwin F. Laing has considerable clinical and laboratory exposure. He was a Member of and now an Affiliate of the American Association for Clinical Chemistry (AACC), a member of the Ghana Medical Association (GMA), a Member of the University Teachers Association of Ghana (UTAG) and a member of the Ghana Science Association (GSA).

Research Summary

(inferred from publications by AI)

The researcher's work in health sciences is centered on understanding the interplay between various biological factors that contribute to cardiovascular disease and other health risks. Their studies span themes such as vitamin D status, glucose metabolism, lipid profiles, metabolic diseases, genetics, anemia, blood pressure, and diabetes. They examine associations with conditions like insulin resistance, glycemic control, cholesterol profiles, and metabolic syndromes, using case-control studies. Additionally, they explore genetic and epidemiological aspects of conditions like sickle cell anemia and sphenocentrum jollyanum root extraction effects. Their research aims to identify high-risk individuals in populations such as Ghana, focusing on preventive strategies and understanding the role of diet, metabolism, lipid dynamics, and genetic factors in disease progression.

Research Themes

All Papers

Vitamin D status and its association with insulin resistance among type 2 diabetics: A case -control study in Ghana(2017)
Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis(2018)
Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study(2021)
Association between vitamin D receptor gene variants and the risk of type 2 diabetes mellitus in a Ghanaian population(2025)
Prevalence of metabolic syndrome and the comparison of fasting plasma glucose and HbA1c as the glycemic criterion for MetS definition in non-diabetic population in Ghana(2019)
Anthropometric indices and their cut-off points in relation to type 2 diabetes among Ghanaian migrants and non-migrants: The RODAM study(2021)
Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population(2020)
Analysis of Atherogenic and Anthropometric Profiles of Normotensive and Hypertensive Ghanaians in the Kumasi Metropolis(2015)
Lipid lowering among treated hypertensives in a Ghanaian population(2001)
Increased metformin dosage suppresses pro-inflammatory cytokine levels in systemic circulation and might contribute to its beneficial effects(2021)
Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis(2020)
Profiling immuno-metabolic mediators of vitamin B12 deficiency among metformin-treated type 2 diabetic patients in Ghana(2021)
Vitamin B<sub>12</sub> deficiency in type 2 diabetic patients on metformin: a cross-sectional study from South-Western part of Ghana(2019)
Profiling Immuno-Metabolic Mediators of Vitamin B12 Deficiency Among Metformin-Treated Type II Diabetes Patients in Ghana(2020)
Thyroid dysfunction and glycaemic control among Type 2 diabetes mellitus patients in Ghana: A comparative cross‐sectional study(2023)
Anxiogenic-like Effects of a Root Extract of Sphenocentrum jollyanum Pierre in Murine Behavioural Models(2009)
Evaluation of serum iron overload, AST:ALT ratio and log10ferritin:AST ratio among schizophrenia patients in the Kumasi Metropolis, Ghana: a case–control study(2019)
Haemato-biochemical basis of anaemia in Agogo, Ashanti Region, Ghana(2017)
Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients(2023)
Differences in PPD- and mitogen-induced T-cell activation marker expression characterize immunopathology in acute tuberculosis patients(2024)
Relationship between parathyroid hormone and electrolytes in chronic kidney disease(2012)
An Analysis of Anthropometric Indicators and Modifiable Lifestyle Parameters Associated with Hypertensive Nephropathy(2016)
Gender Specific Predictive Performance and Optimal Threshold of Anthropometric Indices for the Prediction of Hypertension among a Ghanaian Population in Kumasi(2018)
Nomogram for predicting the probability of the positive outcome of prostate biopsies among Ghanaian men(2018)
A Study of the Efficacy of Cardiac Antidysrhythmic Drugs in Attenuating Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation in the Black Population(2014)
Anaemia as a Risk Factor for Cardiovascular Disease in Patients with Chronic Kidney Disease(2008)
Haplotype-Specific Genetic Epidemiology of Sickle Cell Anemia Patients in Accra, Ghana: Patterns, Clinical Implications, and Public Health Responses(2025)
Identification of hematological biomarkers and assessment of machine learning models for sickle cell anemia severity classification(2025)
Diet-induced obesity influences atherogenic indices and increases risk of cardiovascular disease in male Wistar rats(2025)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.