Christian Obirikorang

Molecular Medicine

About

He is a trained Laboratory Scientist with a specialization (Ph.D.) in Chemical Pathology. Currently, he is an Associate Professor at the Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana lecturing Chemical Pathology and Biochemistry to students offering BSc. Human Biology, Medical Laboratory Technology, Nursing, Veterinary Medicine and Pharmacy. He is a Research Fellow with the Global Health and Infectious Disease Group at KCCR. He has more than Eighteen (18) years of training in the extensive practice of Laboratory Science (Clinical) in the specialized areas of Clinical Chemistry, Immunology, and Molecular Biology.He had a postdoc training at the Department of Human Genetics, the University of Michigan for six months in techniques for identifying Single Nucleotide Polymorphism using the Ligation detection reaction (LDR) for typing single base mutations or polymorphism. This further enhanced his molecular and cellular biology. He worked with the H3 Africa lab (Noguchi Memorial Institute) where he served as a Laboratory Consultant responsible for training research scientists in the use of PCR-LDR techniques for SNPs identification.His area of research is looking at the Genetic basis of diseases. He has worked on SNPs in the SLC10A1 gene among Ghanaians infected with the Hepatitis B virus, Genetic markers (SNPs) associated with dyslipidemia in HIV on Antiretroviral therapy, and TCF7L2 gene association with Type 2 Diabetes. Currently working on various SNPs and their role in varying diseases. He has over 70 publications in referred journals.

Research Summary

(inferred from publications by AI)

Certainly! Here's a summary of the health and life sciences topics related to Ghana: ### 1. **Diseases and Conditions** - **Infectious Diseases**: Types of infections (e.g., HIV/AIDS, SARS-CoV-2) in Ghana. - **Pneumonia**: Analysis of respiratory infections in young students. - **Diabetes**: Studies on diabetes diagnosis, management, and complications. - **Gastrointestinal Disorders**: Conditions such as irritable bowel syndrome and lactose intolerance. - **Bodily777 Project**: Research on postpartum depression and its relation to pregnancy. ### 2. **Therapy and Treatment** - **Neurological Disorders**: Studies on stroke, epilepsy, and Parkinson’s disease in Ghana. - **Osteoporosis and Related Conditions**: Analysis of bone density and calcium deficiency in vulnerable populations. - **Cancer Research**: Overview of breast, prostate, and lung cancer treatments in Ghana. - **Prenatal Health**: Effects of birth control on reproductive health outcomes. ### 3. **Maternal and Child Health** - **Child Nutrition and Water Access**: Impact of water supply on child development. - **Reproductive Health**: Seminal antioxidant capacity and its effects on sperm quality. - **Fertility and Reproductive Biology**: Effects of electromagnetic waves on fertility. ### 4. **Health Technologies and Research** - **Viral Infections**: Detection and testing methods for viruses like SARS-CoV-2 in Ghana. - **Cancer Survival Rates**: Long-term outcomes of cancer patients in developing countries. - **Epidemiological Studies**: Population-level data on chronic diseases. ### 5. **Healthcare and Education** - **Maternal Mental Health**: Risk factors for malnutrition. - **Global Cancer Incidence**: Analysis of cancer rates in Ghana’s population. - **Reproductive Health Tools**: Role of water, sanitation, and education in improving fertility. ### 6. **Health Research Methodologies** - **Medical Testing**: Rapid diagnostic methods for infectious diseases in Ghana. - **Cancer Diagnosis and Treatment**: Identification of high-risk populations for cancer screening. - **Maternal and Child Health Programs**: Preparation and implementation of health care services. This summary categorizes the health and life sciences topics related to Ghana into disease types, patient demographics, methodologies, and broader societal issues. Each topic is further broken down into specific areas such as infectious diseases, diabetes, gut microbiota, maternal health, and global health trends.

Research Themes

All Papers

Oxidative stress and respiratory symptoms due to human exposure to polycyclic aromatic hydrocarbons (PAHs) in Kumasi, Ghana(2017)

Knowledge of complications of diabetes mellitus among patients visiting the diabetes clinic at Sampa Government Hospital, Ghana: a descriptive study(2016)

Prevalence of preeclampsia and algorithm of adverse foeto-maternal risk factors among pregnant women in the Central Region of Ghana: A multicentre prospective cross-sectional study(2023)

Adverse pregnancy outcomes and imbalance in angiogenic growth mediators and oxidative stress biomarkers is associated with advanced maternal age births: A prospective cohort study in Ghana(2018)

Early gestational profiling of oxidative stress and angiogenic growth mediators as predictive, preventive and personalised (3P) medical approach to identify suboptimal health pregnant mothers likely to develop preeclampsia(2021)

Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia(2022)

Association between micronutrients, oxidative stress biomarkers and angiogenic growth mediators in early and late-onset preeclamptic Ghanaian women(2023)

Evaluating circulating soluble markers of endothelial dysfunction and risk factors associated with PE: A multicentre longitudinal case control study in northern Ghana(2023)

Angiogenic growth factors, oxidative stress and haematobiochemical measures as predictors of preeclampsia with and without foetal growth restriction: A case-control study in a Ghanaian population(2023)

Blood haemoglobin measurement as a predictive indicator for the progression of HIV/AIDS in resource-limited setting(2009)

Prevalence of metabolic syndrome among HIV-infected patients in Ghana: A cross-sectional study(2016)

Hepatic Enzyme Alterations in HIV Patients on Antiretroviral Therapy: A Case-Control Study in a Hospital Setting in Ghana(2015)

Renal Function in Ghanaian HIV-Infected Patients on Highly Active Antiretroviral Therapy: A Case-Control Study(2014)

Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study(2020)

Serum Lipid Profiling In Highly Active Antiretroviral Therapy-NaÃƒÂ¯ve HIV Positive Patients In Ghana; Any Potential Risk?(2011)

Single nucleotide polymorphisms in LCAT may contribute to dyslipidaemia in HIV-infected individuals on HAART in a Ghanaian population(2020)

Antioxidant Therapy- A Relevant Therapeutic Adjunct For Antiretroviral Therapy In Plwhas In Ghana(2010)

Nephroprotective Effect of Highly Active Antiretroviral Therapy among HIV Seropositive Individuals: A Case-Control Study in Ghana(2018)

Predictors of Adherence to Antiretroviral Therapy among HIV/AIDS Patients in the Upper West Region of Ghana(2013)

Viral Suppression and Its Associated Factors in HIV Patients on Highly Active Antiretroviral Therapy (HAART): A Retrospective Study in the Ho Municipality, Ghana(2020)

Quality of Life of People Living with HIV/AIDS in the Ho Municipality, Ghana: A Cross-Sectional Study(2017)

Prevalence and lifestyle-related risk factors of obesity and unrecognized hypertension among bus drivers in Ghana(2020)

Obesity and Cardio-Metabolic Risk Factors in an Urban and Rural Population in the Ashanti Region-Ghana: A Comparative Cross-Sectional Study(2015)

Weight management among school-aged children and adolescents: a quantitative assessment in a Ghanaian municipality(2019)

Weight Management among School-Aged Children and Adolescents: A Quantitative Assessment in a Ghanaian Municipality(2019)

Knowledge and Lifestyle-Associated Prevalence of Obesity among Newly Diagnosed Type II Diabetes Mellitus Patients Attending Diabetic Clinic at Komfo Anokye Teaching Hospital, Kumasi, Ghana: A Hospital-Based Cross-Sectional Study(2016)

Association of Wrist Circumference and Waist-to-Height Ratio with Cardiometabolic Risk Factors among Type II Diabetics in a Ghanaian Population(2018)

Prevalence of Cardiometabolic Syndrome and its Association With Body Shape Index and A Body Roundness Index Among Type 2 Diabetes Mellitus Patients: A Hospital-Based Cross-Sectional Study in a Ghanaian Population(2022)

Cardiometabolic syndrome among general adult population in Ghana: The role of lipid accumulation product, waist circumference‐triglyceride index, and triglyceride‐glucose index as surrogate indicators(2023)

Prevalence, knowledge, and lifestyle‐associated risk factors of dyslipidemia among Ghanaian type‐2 diabetes mellitus patients in rural and urban areas: A multicenter cross‐sectional study(2023)

Lipid accumulation product (LAP) index as a potential risk assessment for cardiovascular risk stratification among type II diabetes mellitus in a Ghanaian population: A cross-sectional study(2019)

Biomarkers of renal dysfunction among Ghanaian patients with type 2 diabetes mellitus- a cross-sectional study(2018)

Association between Anthropometry, Dyslipidaemia and the Ten-Year Relative Risk of Cardiovascular Disease in Ghanaians with Type 2 Diabetes and Hypertension at the Battor Catholic Hospital(2017)

Association between human exposure to heavy metals/metalloid and occurrences of respiratory diseases, lipid peroxidation and DNA damage in Kumasi, Ghana(2017)

Total lymphocyte count as a surrogate marker for CD4 count in resource-limited settings(2012)

Prevalence of pre-hypertension and hypertension and its related risk factors among undergraduate students in a Tertiary institution, Ghana(2018)

Predictors of Noncompliance to Antihypertensive Therapy among Hypertensive Patients Ghana: Application of Health Belief Model(2018)

Adherence to Lifestyle Modification among Hypertensive Clients: A Descriptive Cross-Sectional Study(2018)

Unrecognized hypertension among a general adult Ghanaian population: An urban community-based cross-sectional study of prevalence and putative risk factors of lifestyle and obesity indices(2023)

Effects of water flow rates on growth and welfare of Nile tilapia (Oreochromis niloticus) reared in a recirculating aquaculture system(2019)

Anaemia and Iron Homeostasis in a Cohort of HIV-Infected Patients: A Cross-Sectional Study in Ghana(2016)

Evaluation of serum iron overload, AST:ALT ratio and log10ferritin:AST ratio among schizophrenia patients in the Kumasi Metropolis, Ghana: a case–control study(2019)

Predictive model and feature importance for early detection of type II diabetes mellitus(2021)

Predictive modelling of metabolic syndrome in Ghanaian diabetic patients: an ensemble machine learning approach(2024)

Predictive Model and Feature Importance for Early Detection of Type II Diabetes Mellitus(2021)

High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study(2022)

Hypertension and obesity comorbidities increases coronary risk, affects domains of sexual function and sexual quality of life(2017)

Sexual dysfunction among diabetics and its impact on the SQoL of their partners(2017)

Prevalence and Risk Factors of Preterm Birth Among Pregnant Women Admitted at the Labor Ward of the Komfo Anokye Teaching Hospital, Ghana(2022)

The relevance of knowledge, perception, and factors that influence contraceptive use among married women living in Uaddara Barracks, Ghana(2023)

Diagnostic value of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for detection of renal failure in hypertensives: a case–control study in a regional hospital in Ghana(2023)

Association between Interleukin-6 Gene Polymorphism (rs1800795 and rs1800796) and Type 2 Diabetes Mellitus in a Ghanaian Population: A Case-Control Study in the Ho Municipality(2024)

Colorectal cancer survival rates in Ghana: A retrospective hospital-based study(2018)

Patterns and presentations of colorectal cancer at Komfo-Anokye teaching hospital Kumasi, Ghana(2017)

Physical Activity Pattern and Its Association with Glycaemic and Blood Pressure Control among People Living with Diabetes (PLWD) In The Ho Municipality, Ghana(1970)

Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis(2020)

Association between Transcription Factor 7-like-2 Polymorphisms and Type 2 Diabetes Mellitus in a Ghanaian Population(2021)

Assessing the variability and predictability of adipokines (adiponectin, leptin, resistin and their ratios) in non-obese and obese women with anovulatory polycystic ovary syndrome(2019)

Weight management merits attention in women with infertility: a cross-sectional study on the association of anthropometric indices with hormonal imbalance in a Ghanaian population(2019)

Assessing the variability and predictability of adipokines (adiponectin, leptin, resistin and their ratios) in non-obese and obese women with anovulatory polycystic ovary syndrome(2019)

Evidence of reduced academic performance among schoolchildren with helminth infection(2022)

Metabolic Syndrome among Schizophrenic Patients: A Comparative Cross-Sectional Study in the Middle Belt of Ghana(2018)

Awareness and Occupational Exposures to Needlestick Injuries among Healthcare Workers: A Quantitative Assessment in a Ghanaian Metropolis(2019)

Prognostic Worth of Epidermal Growth Factor Receptor (EGFR) in Patients with Head and Neck Tumors(2020)

Human Papillomavirus Detection in Head and Neck Squamous Cell Carcinomas at a Tertiary Hospital in Sub-Saharan Africa(2019)

Profiling vitamin D, its mediators and proinflammatory cytokines in rheumatoid arthritis: A case–control study(2022)

Predictors of medication nonadherence among hypertensive clients in a Ghanaian population: Application of the Hill‐Bone and Perceived Barriers to Treatment Compliance Scale(2022)

Prevalence and risk factors of obesity among undergraduate student population in Ghana: an evaluation study of body composition indices(2024)

Abdominal volume index is a better predictor of visceral fat in patients with type 2 diabetes: a cross-sectional study in Ho municipality, Ghana(2022)

Comparative analysis of breast cancer characteristics in young premenopausal and postmenopausal women in Ghana(2024)

Association between Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and hypertension in a Ghanaian population(2024)

Renal abnormalities among children with sickle cell conditions in highly resource-limited setting in Ghana(2019)

Prevalence and risk factors of obesity among practicing nurses at three selected hospitals in Kumasi Metropolis, Ghana(2017)

NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population(2020)

Factors associated with knowledge, attitude and practice towards hepatitis B infection among pregnant women attending antenatal clinic in the Kumasi Metropolis, Ghana: a multi-centre hospital-based cross-sectional study(2020)

Prevalence of Helicobacter pylori, Salmonella typhi, Plasmodium falciparum, and Toxoplasma gondii infections and levels of liver function markers among Hepatitis B Virus infected Ghanaians: A cross-sectional study in the Greater Accra Region(2025)

NTCP gene polymorphisms and Hepatitis B virus infection status in a Ghanaian population(2020)

Association of MYH9-rs3752462 polymorphisms with chronic kidney disease among clinically diagnosed hypertensive patients: a case-control study in a Ghanaian population(2020)

SARS-CoV-2 updates in a West African population and precautionary measures for sustaining quality antenatal care delivery(2020)

Assessment of the performance of haematological and non-invasive fibrotic indices for the monitoring of chronic HBV infection: a pilot study in a Ghanaian population(2023)

Evaluation of Dyslipidaemia Using an Algorithm of Lipid Profile Measures among Newly Diagnosed Type II Diabetes Mellitus Patients: A Cross-Sectional Study at Dormaa Presbyterian Hospital, Ghana(2019)

Evaluation of Four Malaria Rapid Diagnostic Test Kits Used at the Enyiresi Government Hospital in the Eastern Region of Ghana(2023)

Nexus between constructs of social cognitive theory model and diabetes self-management among Ghanaian diabetic patients: A mediation modelling approach(2022)

Assessment of vitamin D levels and adipokines mediated obesity among psychiatric patients on treatment and treatment naïve: A comparative cross‐sectional study(2022)

Quality of life of colorectal cancer survivors in a Ghanaian population(2019)

Association of genetic variants with prostate cancer in Africa: a concise review(2021)

Knowledge of bloodless medicine among nurses at the Medical/Surgical Directorate of Komfo Anokye Teaching Hospital, Ghana; a descriptive cross sectional study(2017)

Influence of K2EDTA, sodium citrate and lithium heparin anticoagulants on lipid profile in plasma samples as measured by an automated chemical analyzer(2017)

Putative factors influencing knowledge and behavioural practices of health science undergraduate students towards COVID-19 infection ahead of re-opening universities in Ghana(2021)

Nomogram for predicting the probability of the positive outcome of prostate biopsies among Ghanaian men(2018)

Elevated Serum Sialic Acid Levels May be Associated With Diabetes Retinopathy: A Cross-Sectional Study in Ghana(2022)

An Evaluation of the Sensitivity and Specificity of Three COVID-19 Rapid Immunochromatographic Test Kits Compared to Real-Time Reverse Transcriptase-Polymerase Chain Reaction (rRT-PCR) Among Clinical Samples(2024)

Prevalence and risk factors of postpartum depression among postnatal mothers with hypertensive disorders of pregnancy in a developing country(2025)

Breast Cancer Awareness and Knowledge Among Women at a Municipal Hospital in Ghana: A Cross‐Sectional Study(2025)

Seminal Antioxidant Capacity to Oxidative Stress Induced by Electromagnetic Waves Emitting from Cellular Phones on Sperm Quality: An &lt;i&gt;in Vitro&lt;/i&gt; Simulation Model(2019)

Evaluation of Individual and Combined Markers of Urine Dipstick Parameters and Total Lymphocyte Count as a Substitute for CD4 Count in Low-Resource Communities in Ghana(2018)

Weight Management Merits Attention in women with infertility: A Cross-Sectional Study on the Association of Anthropometric Indices with Hormonal Imbalance in a Ghanaian Population(2019)

Immediate Risk Factor Associated with Child Malnutrition in Ghana; A Critical Analysis of the Ashiedu Keteke Sub-Metro Area in Accra(2015)

CoViD-19 rRT-PCR Testing Capacity in Ghana; Indications of Preparedness for Marburg virus Outbreak?(2022)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.