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Arnold Forkuo Donkor

Pharmacology

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About

Dr Arnold Forkuo Donkor is a Lecturer in the Department of Pharmacology, Kwame Nkrumah University of Science and Technology, Kumasi Ghana. His research interests focusses on medicinal plants - mainly on the evaluation of novel compounds from these natural products for the treatment of malaria, schistosomiasis, inflammation and the pharmacokinetics of these plant derived bioactive compounds in vivo and in vitro.  Additionally, Dr Forkuo’s research also focusses on monitoring of the adverse effects of these natural products (Pharmacovigilance) and the elucidation of their mechanism(s) of action in these adverse effects.He holds a Bachelor of Pharmacy (First class honors) and a PhD in Pharmacology all from the Kwame Nkrumah University of Science and Technology, Kumasi in 2011 and 2016 respectively. He also holds a University Certificate of Advanced Studies from the University of Basel and Novartis Pharma AG, Basel Switzerland as part of the Next Generation Scientist Program in 2014.In 2018, he undertook the International Zebrafish and Medaka course (FELASA) at Karlshule Institute of Technology (KIT), Germany to equip him with the skills to use Zebrafish and Medaka as a biological, toxicological and biomedical research tool in his research.Over the past four years, he has been involved in research toHe has on-going collaborations with colleagues within and outside the college. He has co-won two (2) KNUST Research Fund (KReF) as a results of these collaboration. He is part of the KNUST researchers repurposing Cryptolepis sanguinolenta, a popular antimalarial plant, for COVID 19. He has sixteen (16) peer-reviewed articles, two (2) book chapter and two (2) peer-reviewed abstracts out of his research work. Most of these are published in open-access journals to enhance their visibility and thus promote their increased usage and impact.His research publications are indexed in several scholarly databases including PubMed, Scopus, Web of Science, Thomson ISI, Google Scholar, African Journals Online (AJOL), Hinari, Directory of Open Access Journals (DOAJ), etc. Some of his research findings have also been presented at scientific conferences both local and international.His research work has good visibility and as such well cited by other researchers. He has an h-index and i10-index of 7 and 5 respectively for his efforts documented on his profile page in Google Scholar (https://scholar.google.com/citations?user=qIRtHIwAAAAJ&hl=en&oi=ao) and h-index of 6 on Elsevier’s Scopus. He has a RG score of 16.67 and h-index of 7 on ResearchGate (https://www.researchgate.net/profile/Arnold_Donkor).In all the publications listed below, he made major contribution(s) to the conception/design of the work, the acquisition, analysis, and interpretation of data for the work. Additionally, he drafted or co-drafted the work and/or revised it critically for important intellectual content.He is co-supervising two (2) PhD candidate and seven (7) MPhil candidates at various stages of their projects.

Research Summary

(inferred from publications by AI)

The researcher's work integrates ethn botany into pharmacological studies, focusing on the effects of herbal and traditional plant-based compounds in African contexts. Their research encompasses the ethical and safety implications of herbal medicines, immunological investigations into human immune responses, studies of skin diseases linked to antimalarials, and explorations of alkaloid metabolism and their therapeutic potential, particularly in controlling malaria. Additionally, they examine the pharmacovigilance practices related to herbal medicine use in Ghana and explore the pharmacokinetic properties of plant-derived compounds using mathematical modeling techniques. Their work also delves into the ethical considerations in traditional materials' application in modern healthcare settings.

Research Themes

All Papers

Toxicity and Safety Implications of Herbal Medicines Used in Africa(2019)
Antimalarial Drugs in Ghana: A Case Study on Personal Preferences(2020)
Antimalarial Drugs in Ghana: A Case Study on Personal Preferences(2020)
Antimalarial Drugs in Ghana: A Case Study on Personal Preferences(2020)
Stigmasterol inhibits lipopolysaccharide-induced innate immune responses in murine models(2017)
Stigmasterol Alleviates Cutaneous Allergic Responses in Rodents(2018)
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine(2017)
Synergistic anti-malarial action of cryptolepine and artemisinins(2016)
Cryptolepine, an indoloquinoline alkaloid, in the management of diabetes mellitus and its associated complications(2016)
Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer(2022)
Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei(2018)
Cryptolepine, the Main Alkaloid of the Antimalarial <i>Cryptolepis sanguinolenta</i> (Lindl.) Schlechter, Induces Malformations in Zebrafish Embryos(2019)
Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats(2017)
Cryptolepine, the major alkaloid of Cryptolepis sanguinolenta (Lindl.) Schlechter (Apocynaceae), attenuates early and late-phase symptoms of asthma(2020)
Erratum to: Synergistic anti-malarial action of cryptolepine and artemisinins(2016)
In vitro antimalarial interaction and transmission-blocking activity of cryptolepine(2016)
Tenofovir-Based Highly Active Antiretroviral Therapy Is Associated with Superior CD4 T Cells Repopulation Compared to Zidovudine-Based HAART in HIV 1 Infected Adults(2018)
<i>In Vivo</i> Antiplasmodial Activity of Different Solvent Extracts of <i>Myrianthus libericus</i> Stem Bark and Its Constituents in <i>Plasmodium berghei</i>‐Infected Mice(2020)
Malaria: Cellular Understanding of Disease(2023)
In vivo anti-plasmodial activity of alpha-onocerin and artesunate combination against Plasmodium berghei infected mice(2025)
Ethnobotanical Survey and Cercaricidal Activity Screening of Medicinal Plants Used for Schistosomiasis Treatment in Atwima-Nwabiagya District, Ashanti Region, Ghana(2023)
The Ghanaian Flora as a Potential Source of Anthelmintic and Anti-Schistosomal Agents(2021)
Corrigendum: The Ghanaian Flora as a Potential Source of Anthelmintic and Anti-Schistosomal Agents(2021)
Ethanolic stem bark extract of Terminalia ivorensis A. Chev. protects against potassium dichromate–induced nephrotoxicity in rats(2020)
Antiplasmodial and Antipyretic Activity and Safety Evaluation of the Methanolic Leaf Extract of <i>Murraya exotica (L.)</i>(2020)
Antimalarial activity of the aqueous extract and anthraquinones from the root of Senna siamea (LAM) H.S. Irwin &amp; Barneby (Fabaceae).(2025)
Antimalarial Property and Acute Toxicity of the Leaves of Theobroma cacao L.(2021)
A Study on Justicia flava (Forssk.) Vahl.: Pharmacognostic Characterization and Antiplasmodial and Anti-Inflammatory Properties of the Leaves(2023)
In Vivo Antimalarial Activity of Polyalthia longifolia (Annonaceae) Leaf Extract and Assessment of Its Formulated Oral Dosage Forms(2021)
In Vitro and In Vivo Effect of Xylopic Acid on Cytochrome P450 Enzymes(2022)
Pharmacovigilance of herbal medicines in Ghana- Knowledge, perception and practice(2025)
CCDC 2155900: Experimental Crystal Structure Determination(2022)
CCDC 2155899: Experimental Crystal Structure Determination(2022)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.